Goat Anti-FPRL1 Polyclonal Antibody – Cat# MBS418548

FPRL1 Antibody – Goat Polyclonal

Name: FPRL1 Antibody; Polyclonal; Goat; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS418548
Price: 460 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS418548

MBS418548 is an antibody targeting FPRL1. Also known as Anti-FPRL1 (aa13-26) Antibody. Reactive in Human. Host: Goat. More details

DISCONTINUED
Click here to view our similar product(s) OR click here to contact our technical support team for suitable replacement.

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

FPRL1, Polyclonal Antibody

Full Product Name

Anti-FPRL1 (aa13-26) Antibody

Product Gene Name

anti-FPRL1 antibody

Clonality

Polyclonal

Isotype

IgG

Host

Goat

Species Reactivity

Human

Form/Format

Liquid

Purity/Purification

Affinity Purified

Concentration

100ug/200ul (lot specific)

Preparation and Storage

This product is stable for several weeks at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20 degree C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.

Molecular Weight

38,964 Da

OMIM

M76672 mRNA

Immunogen

EEVSYESAGYTVLR

Storage Buffer

Supplied at 0.5 mg/ml in Tris saline,0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin

Applications Tested/Suitable for anti-FPRL1 antibody

Western Blot (WB), ELISA (EIA)

Other Notes

Small volumes of anti-FPRL1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for FPRL1. It may not necessarily be applicable to this product.

NCBI GI #

9454518

NCBI GeneID

2358

NCBI Accession #

AAF87844.1

UniProt Secondary Accession #

A8K3E2

UniProt Related Accession #

P25090; AAB23104

NCBI Official Full Name

formyl peptide receptor-like 1

NCBI Official Synonym Full Names

formyl peptide receptor 2

NCBI Official Symbol

FPR2

NCBI Official Synonym Symbols

ALXR; HM63; FMLPX; FPR2A; FPRH1; FPRH2; FPRL1; LXA4R; FMLP-R-II

UniProt Protein Name

N-formyl peptide receptor 2

UniProt Synonym Protein Names

FMLP-related receptor I; FMLP-R-I; Formyl peptide receptor-like 1; HM63; Lipoxin A4 receptor; LXA4 receptor; RFP

Protein Family

FPRL1 inhibitory protein

UniProt Gene Name

FPR2

UniProt Synonym Gene Names

FPRH1; FPRL1; LXA4R; FMLP-R-I; LXA4 receptor

NCBI Protein Information

N-formyl peptide receptor 2

UniProt Comments for FPRL1

FPR2: Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The activation of LXA4R could result in an anti-inflammatory outcome counteracting the actions of proinflammatory signals such as LTB4 (leukotriene B4). Belongs to the G-protein coupled receptor 1 family.

Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Motility/polarity/chemotaxis; Receptor, GPCR

Chromosomal Location of Human Ortholog: 19q13.41

Cellular Component: integral to membrane; integral to plasma membrane; plasma membrane

Molecular Function: complement receptor activity; G-protein coupled receptor activity

Biological Process: cell adhesion; cell motility; chemotaxis; complement receptor mediated signaling pathway; elevation of cytosolic calcium ion concentration; G-protein coupled receptor protein signaling pathway; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); inflammatory response; leukocyte migration

Research Articles on FPRL1

1. We conclude that ANX-A1 is an important regulator of mast cell reactivity to compound 48/80 exerting a negative feedback effect through a mechanism that depends at least partly on the FPR receptor

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-FPRL1 antibody

Reference Product	PubMed Publications
FPR1 antibody	>77 publications with FPRL1 and FPR1
ANXA1 antibody	>25 publications with FPRL1 and ANXA1
CXCR2 antibody	>6 publications with FPRL1 and CXCR2
CXCR1 antibody	>5 publications with FPRL1 and CXCR1
CCR1 antibody	>3 publications with FPRL1 and CCR1
PLAUR antibody	>3 publications with FPRL1 and PLAUR
APP antibody	>2 publications with FPRL1 and APP

Pathways associated with anti-FPRL1 antibody

Products by Pathway	Pathway Diagram
Class A/1 (Rhodopsin-like Receptors) Pathway antibodies	Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway antibodies	Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway Diagram
Disease Pathway antibodies	Disease Pathway Diagram
Formyl Peptide Receptors Bind Formyl Peptides And Many Other Ligands Pathway antibodies	Formyl Peptide Receptors Bind Formyl Peptides And Many Other Ligands Pathway Diagram
G Alpha (i) Signalling Events Pathway antibodies	G Alpha (i) Signalling Events Pathway Diagram
G Alpha (q) Signalling Events Pathway antibodies	G Alpha (q) Signalling Events Pathway Diagram
GPCR Downstream Signaling Pathway antibodies	GPCR Downstream Signaling Pathway Diagram
GPCR Ligand Binding Pathway antibodies	GPCR Ligand Binding Pathway Diagram
GPCRs, Class A Rhodopsin-like Pathway antibodies	GPCRs, Class A Rhodopsin-like Pathway Diagram
Gastrin-CREB Signalling Pathway Via PKC And MAPK antibodies	Gastrin-CREB Signalling Pathway Via PKC And MAPK Diagram

Diseases associated with anti-FPRL1 antibody

Disease Name	Pubmed Publications
Inflammation Antibodies	>196 publications with FPRL1 and Inflammation
Necrosis Antibodies	>30 publications with FPRL1 and Necrosis
Lung Diseases Antibodies	>27 publications with FPRL1 and Lung Diseases
Vascular Diseases Antibodies	>17 publications with FPRL1 and Vascular Diseases
Autoimmune Diseases Antibodies	>15 publications with FPRL1 and Autoimmune Diseases
Lung Injury Antibodies	>9 publications with FPRL1 and Lung Injury
Fibrosis Antibodies	>9 publications with FPRL1 and Fibrosis
Respiratory Hypersensitivity Antibodies	>8 publications with FPRL1 and Respiratory Hypersensitivity
Carcinoma Antibodies	>7 publications with FPRL1 and Carcinoma
Respiratory Tract Infections Antibodies	>6 publications with FPRL1 and Respiratory Tract Infections

Organs/Tissues associated with anti-FPRL1 antibody

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>198 publications with FPRL1 and Blood
Lung Antibodies	>49 publications with FPRL1 and Lung
Kidney Antibodies	>13 publications with FPRL1 and Kidney
Bone Marrow Antibodies	>12 publications with FPRL1 and Bone Marrow
Spleen Antibodies	>8 publications with FPRL1 and Spleen
Heart Antibodies	>7 publications with FPRL1 and Heart
Connective Tissue Antibodies	>6 publications with FPRL1 and Connective Tissue
Placenta Antibodies	>3 publications with FPRL1 and Placenta
Testis Antibodies	>1 publications with FPRL1 and Testis