Rabbit Anti-RNF144B Antibody – Cat# MBS004187

RNF144B Antibody – Rabbit

Name: RNF144B Antibody; Rabbit; Human/Mouse-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS004187
Price: 595 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS004187

MBS004187 is an antibody targeting RNF144B. Also known as Rabbit RNF144B Antibody. Reactive in Human, mouse. Host: Rabbit. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

RNF144B, Antibody

Full Product Name

Rabbit RNF144B Antibody

Product Gene Name

anti-RNF144B antibody

Host

Rabbit

Species Reactivity

Human, mouse

Form/Format

Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol

Concentration

1 mg/ml (lot specific)

Specificity

RNF144B antibody detects endogenous levels of total RNF144B protein.

Molecular Weight

33,697 Da

Chromosome Location

Chromosome: 6; NC_000006.11 (18387581..18469105). Location: 6p22.3

3D Structure

ModBase 3D Structure for Q7Z419

Applications Tested/Suitable for anti-RNF144B antibody

ELISA (EIA), Western Blot (WB)

Other Notes

Small volumes of anti-RNF144B antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for RNF144B. It may not necessarily be applicable to this product.

NCBI GI #

50284696

NCBI GeneID

255488

NCBI Accession #

NP_877434.2

UniProt Primary Accession #

Q7Z419

UniProt Secondary Accession #

Q5TB85; Q6P4Q0; Q8N3R7; Q9BX38; B3KUA8

UniProt Related Accession #

Q7Z419

GenBank Nucleotide #

NM_182757.3

NCBI Official Full Name

E3 ubiquitin-protein ligase RNF144B

NCBI Official Synonym Full Names

ring finger protein 144B

NCBI Official Symbol

RNF144B

NCBI Official Synonym Symbols

PIR2; IBRDC2; p53RFP; bA528A10.3

UniProt Protein Name

E3 ubiquitin-protein ligase RNF144B

UniProt Synonym Protein Names

IBR domain-containing protein 2; RING finger protein 144B; p53-inducible RING finger protein

Protein Family

E3 ubiquitin-protein ligase

UniProt Gene Name

RNF144B

UniProt Synonym Gene Names

IBRDC2; P53RFP

UniProt Entry Name

R144B_HUMAN

NCBI Protein Information

E3 ubiquitin-protein ligase RNF144B; IBR domain containing 2; IBR domain-containing protein 2; p53-inducible RING finger protein

UniProt Comments for RNF144B

RNF144B: E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates such as LCMT2, thereby promoting their degradation. Induces apoptosis via a p53/TP53-dependent but caspase-independent mechanism. However, its overexpression also produces a decrease of the ubiquitin-dependent stability of BAX, a pro-apoptotic protein, ultimately leading to protection of cell death; But, it is not an anti-apoptotic protein per se. Belongs to the RBR family. RNF144 subfamily.

Protein type: Membrane protein, integral; Ubiquitin conjugating system; Ubiquitin ligase; EC 6.3.2.-; EC 6.3.2.19; Ligase

Chromosomal Location of Human Ortholog: 6p22.3

Cellular Component: cytoplasm; mitochondrial membrane; integral to membrane; ubiquitin ligase complex

Molecular Function: protein binding; zinc ion binding; ubiquitin-protein ligase activity; ligase activity

Biological Process: apoptosis; protein ubiquitination during ubiquitin-dependent protein catabolic process

Research Articles on RNF144B

1. PIR2, by being induced by TAp73 and degrading DeltaNp73, differentially regulates TAp73/DeltaNp73 stability.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-RNF144B antibody

Reference Product	PubMed Publications
UBE2L6 antibody	>1 publications with RNF144B and UBE2L6
UBE2L3 antibody	>1 publications with RNF144B and UBE2L3
CDKN1A antibody	>1 publications with RNF144B and CDKN1A

Pathways associated with anti-RNF144B antibody

Products by Pathway	Pathway Diagram
Adaptive Immune System Pathway antibodies	Adaptive Immune System Pathway Diagram
Antigen Processing: Ubiquitination & Proteasome Degradation Pathway antibodies	Antigen Processing: Ubiquitination & Proteasome Degradation Pathway Diagram
Class I MHC Mediated Antigen Processing & Presentation Pathway antibodies	Class I MHC Mediated Antigen Processing & Presentation Pathway Diagram
Direct P53 Effectors Pathway antibodies	Direct P53 Effectors Pathway Diagram
Gastric Cancer Network 2 Pathway antibodies	Gastric Cancer Network 2 Pathway Diagram
Immune System Pathway antibodies	Immune System Pathway Diagram

Diseases associated with anti-RNF144B antibody

Disease Name	Pubmed Publications
Lung Neoplasms Antibodies	>1 publications with RNF144B and Lung Neoplasms
Pain Antibodies	>1 publications with RNF144B and Pain

Organs/Tissues associated with anti-RNF144B antibody

Organ/Tissue Name	Pubmed Publications
Lung Antibodies	>1 publications with RNF144B and Lung