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Plexin D1 (PLXND1) Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS418918

MBS418918 is an antibody targeting PLXND1. Also known as Anti-Plexin D1 Antibody. Reactive in Human, Bovine, Other. Host: Goat. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Plexin D1 (PLXND1), Polyclonal Antibody
Full Product Name
Anti-Plexin D1 Antibody
Product Gene Name
anti-PLXND1 antibody
Clonality
Polyclonal
Isotype
IgG
Host
Goat
Species Reactivity
Human, Bovine, Other
Form/Format
Liquid
Purity/Purification
Affinity Purified
Concentration
100ug/200ul (lot specific)
Preparation and Storage
This product is stable for several weeks at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20 degree C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Molecular Weight
195,558 Da
OMIM
AB014520 mRNA
Immunogen
LAEPKKSHRQSH
Storage Buffer
Supplied at 0.5 mg/ml in Tris saline,0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
Applications Tested/Suitable for anti-PLXND1 antibody
Western Blot (WB), ELISA (EIA)

Other Notes

Small volumes of anti-PLXND1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PLXND1. It may not necessarily be applicable to this product.

NCBI GI #
24953987
NCBI GeneID
23129
NCBI Accession #
AAM49063.1
UniProt Secondary Accession #
Q6PJS9; Q8IZJ2; Q9BTQ2; A7E2C6; C9JPZ6
UniProt Related Accession #
Q9Y4D7
NCBI Official Full Name
plexin D1
NCBI Official Synonym Full Names
plexin D1
NCBI Official Symbol
PLXND1
NCBI Official Synonym Symbols
PLEXD1
UniProt Protein Name
Plexin-D1
Protein Family
Plexin
UniProt Gene Name
PLXND1
UniProt Synonym Gene Names
KIAA0620
NCBI Protein Information
plexin-D1

UniProt Comments for PLXND1

PLXND1: Cell surface receptor for SEMA4A and for class 3 semaphorins, such as SEMA3A, SEMA3C and SEMA3E. Plays an important role in cell-cell signaling, and in regulating the migration of a wide spectrum of cell types. Regulates the migration of thymocytes in the medulla. Regulates endothelial cell migration. Plays an important role in ensuring the specificity of synapse formation. Required for normal development of the heart and vasculature. Mediates anti-angiogenic signaling in response to SEMA3E. Belongs to the plexin family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Receptor, misc.

Chromosomal Location of Human Ortholog: 3q22.1

Cellular Component: integral to plasma membrane; lamellipodium; plasma membrane

Molecular Function: protein binding; protein domain specific binding; semaphorin receptor activity

Biological Process: angiogenesis; branchiomotor neuron axon guidance; endothelial cell migration; regulation of angiogenesis; regulation of axon extension involved in axon guidance; regulation of cell migration; synaptogenesis
Show more

Research Articles on PLXND1

1. Plexin D1 plays a role in collagen contraction in human lung fibroblasts.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-PLXND1 antibody

 Reference Product  PubMed Publications
 SEMA3E antibody  >36 publications with PLXND1 and SEMA3E
 SEMA3C antibody  >5 publications with PLXND1 and SEMA3C
 NRP1 antibody  >4 publications with PLXND1 and NRP1
 RRAS antibody  >3 publications with PLXND1 and RRAS
 SEMA4A antibody  >3 publications with PLXND1 and SEMA4A
 RND2 antibody  >2 publications with PLXND1 and RND2
 VEGFA antibody  >1 publications with PLXND1 and VEGFA

Pathways associated with anti-PLXND1 antibody

 Products by Pathway  Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 Developmental Biology Pathway antibodies  Developmental Biology Pathway Diagram
 Other Semaphorin Interactions Pathway antibodies  Other Semaphorin Interactions Pathway Diagram
 Semaphorin Interactions Pathway antibodies  Semaphorin Interactions Pathway Diagram

Diseases associated with anti-PLXND1 antibody

 Disease Name  Pubmed Publications
 Congenital Abnormalities Antibodies  >7 publications with PLXND1 and Congenital Abnormalities
 Heart Diseases Antibodies  >5 publications with PLXND1 and Heart Diseases
 Lung Diseases Antibodies  >4 publications with PLXND1 and Lung Diseases
 Disease Models, Animal Antibodies  >4 publications with PLXND1 and Disease Models, Animal
 Inflammation Antibodies  >4 publications with PLXND1 and Inflammation
 Brain Diseases Antibodies  >3 publications with PLXND1 and Brain Diseases
 Lung Neoplasms Antibodies  >2 publications with PLXND1 and Lung Neoplasms
 Nerve Degeneration Antibodies  >2 publications with PLXND1 and Nerve Degeneration
 Hypertension Antibodies  >1 publications with PLXND1 and Hypertension
 Fibrosis Antibodies  >1 publications with PLXND1 and Fibrosis

Organs/Tissues associated with anti-PLXND1 antibody

 Organ/Tissue Name  Pubmed Publications
 Nerve Antibodies  >43 publications with PLXND1 and Nerve
 Vascular Antibodies  >36 publications with PLXND1 and Vascular
 Blood Antibodies  >24 publications with PLXND1 and Blood
 Brain Antibodies  >19 publications with PLXND1 and Brain
 Embryonic Tissue Antibodies  >17 publications with PLXND1 and Embryonic Tissue
 Heart Antibodies  >8 publications with PLXND1 and Heart
 Muscle Antibodies  >7 publications with PLXND1 and Muscle
 Lung Antibodies  >5 publications with PLXND1 and Lung
 Adipose Tissue Antibodies  >4 publications with PLXND1 and Adipose Tissue
 Skin Antibodies  >4 publications with PLXND1 and Skin
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