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AMPD1 Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS419066

MBS419066 is an antibody targeting AMPD1. Reactive in Human, Mouse, Rat, Bovine, Other. Host: Goat. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
AMPD1, Polyclonal Antibody
Full Product Name
Anti-AMPD1 Antibody
Product Gene Name
Clonality
Polyclonal
Isotype
IgG
Host
Goat
Species Reactivity
Human, Mouse, Rat, Bovine, Other
Form/Format
Liquid
Purity/Purification
Affinity Purified
Concentration
100ug/200ul (lot specific)
Preparation and Storage
This product is stable for several weeks at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20 degree C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Molecular Weight
89,763 Da
3D Structure
ModBase 3D Structure for P23109
Immunogen
HMFSSKSPKPQE
Storage Buffer
Supplied at 0.5 mg/ml in Tris saline,0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
Applications Tested/Suitable for anti-AMPD1 antibody
Western Blot (WB), ELISA (EIA)

Other Notes

Small volumes of anti-AMPD1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for AMPD1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
AMP deaminase 1 isoform 1
NCBI Official Synonym Full Names
adenosine monophosphate deaminase 1
NCBI Official Symbol
AMPD1
NCBI Official Synonym Symbols
MAD; MADA; MMDD
UniProt Protein Name
AMP deaminase 1
UniProt Synonym Protein Names
AMP deaminase isoform M; Myoadenylate deaminase
Protein Family
UniProt Gene Name
AMPD1
NCBI Protein Information
AMP deaminase 1

NCBI Summary for AMPD1

Adenosine monophosphate deaminase 1 catalyzes the deamination of AMP to IMP in skeletal muscle and plays an important role in the purine nucleotide cycle. Two other genes have been identified, AMPD2 and AMPD3, for the liver- and erythocyte-specific isoforms, respectively. Deficiency of the muscle-specific enzyme is apparently a common cause of exercise-induced myopathy and probably the most common cause of metabolic myopathy in the human. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.[provided by RefSeq, Feb 2010]
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UniProt Comments for AMPD1

AMPD1: AMP deaminase plays a critical role in energy metabolism. Defects in AMPD1 are the cause of adenosine monophosphate deaminase deficiency muscle type (AMPDDM). AMPDDM is a metabolic disorder resulting in exercise-related myopathy. It is characterized by exercise-induced muscle aches, cramps, and early fatigue. Belongs to the adenosine and AMP deaminases family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.5.4.6; Hydrolase; Nucleotide Metabolism - purine

Chromosomal Location of Human Ortholog: 1p13.2

Cellular Component: cytosol

Molecular Function: AMP deaminase activity

Biological Process: purine salvage

Disease: Myopathy Due To Myoadenylate Deaminase Deficiency
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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