Goat Anti-PFKFB2 Polyclonal Antibody – Cat# MBS419267

PFKFB2 Antibody – Goat Polyclonal

Name: PFKFB2 Antibody; Polyclonal; Goat; Human/Bovine-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS419267
Price: 635 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS419267

MBS419267 is an antibody targeting PFKFB2. Reactive in Human, Bovine, Other. Host: Goat. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

PFKFB2, Polyclonal Antibody

Full Product Name

Anti-PFKFB2 Antibody

Product Gene Name

anti-PFKFB2 antibody

Clonality

Polyclonal

Isotype

IgG

Host

Goat

Species Reactivity

Human, Bovine, Other

Form/Format

Liquid

Purity/Purification

Affinity Purified

Concentration

100ug/200ul (lot specific)

Preparation and Storage

This product is stable for several weeks at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20 degree C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.

Molecular Weight

59,925 Da

Immunogen

SEQNNNSYETKTP

Storage Buffer

Supplied at 0.5 mg/ml in Tris saline,0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin

Applications Tested/Suitable for anti-PFKFB2 antibody

Western Blot (WB), ELISA (EIA)

Other Notes

Small volumes of anti-PFKFB2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PFKFB2. It may not necessarily be applicable to this product.

NCBI GI #

17390987

NCBI GeneID

18640

NCBI Accession #

AAH18418.1

UniProt Secondary Accession #

Q8VEI9

UniProt Related Accession #

P70265

NCBI Official Full Name

Pfkfb2 protein

NCBI Official Synonym Full Names

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2

NCBI Official Symbol

Pfkfb2

NCBI Official Synonym Symbols

4930568D07Rik

UniProt Protein Name

6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2

UniProt Synonym Protein Names

6PF-2-K/Fru-2,6-P2ase heart-type isozymeIncluding the following 2 domains:6-phosphofructo-2-kinase (EC:2.7.1.105)Fructose-2,6-bisphosphatase (EC:3.1.3.46)

Protein Family

6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase

UniProt Gene Name

Pfkfb2

UniProt Synonym Gene Names

6PF-2-K/Fru-2,6-P2ase 2; PFK/FBPase 2

NCBI Protein Information

6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2

UniProt Comments for PFKFB2

PFKFB2: a bifunctional heterodimeric enzyme involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. Regulates fructose-2,6-bisphosphate levels in the heart, while a related enzyme encoded by a different gene regulates fructose-2,6-bisphosphate levels in the liver and muscle. Two splice-variant isoforms have been described.

Protein type: Carbohydrate Metabolism - fructose and mannose; EC 2.7.1.105; EC 3.1.3.46; Kinase, other; Motility/polarity/chemotaxis; Phosphatase (non-protein)

Chromosomal Location of Human Ortholog: 1|1 E4

Cellular Component: cytoplasm

Molecular Function: 6-phosphofructo-2-kinase activity; fructose-2,6-bisphosphate 2-phosphatase activity; kinase binding; protein kinase binding

Biological Process: glucose catabolic process; glycolysis; lactate metabolic process; positive regulation of glucokinase activity; positive regulation of insulin secretion; pyruvate metabolic process; response to glucose stimulus

Research Articles on PFKFB2

1. SGK3 is not required for insulin-induced PFK-2 activation and that this effect is likely mediated by PKBalpha.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-PFKFB2 antibody

Products by Pathway	Pathway Diagram
Fructose And Mannose Metabolism Pathway antibodies	Fructose And Mannose Metabolism Pathway Diagram
Fructose And Mannose Metabolism Pathway antibodies	Fructose And Mannose Metabolism Pathway Diagram
Glucose Metabolism Pathway antibodies	Glucose Metabolism Pathway Diagram
Glycolysis Pathway antibodies	Glycolysis Pathway Diagram
Metabolism Of Carbohydrates Pathway antibodies	Metabolism Of Carbohydrates Pathway Diagram

Diseases associated with anti-PFKFB2 antibody

Disease Name	Pubmed Publications
Neoplasms Antibodies	>4 publications with PFKFB2 and Neoplasms
Prostatic Neoplasms Antibodies	>1 publications with PFKFB2 and Prostatic Neoplasms
Growth Disorders Antibodies	>1 publications with PFKFB2 and Growth Disorders
Brain Neoplasms Antibodies	>1 publications with PFKFB2 and Brain Neoplasms
Fetal Growth Retardation Antibodies	>1 publications with PFKFB2 and Fetal Growth Retardation
Death Antibodies	>1 publications with PFKFB2 and Death

Organs/Tissues associated with anti-PFKFB2 antibody

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>4 publications with PFKFB2 and Blood
Muscle Antibodies	>3 publications with PFKFB2 and Muscle
Heart Antibodies	>3 publications with PFKFB2 and Heart
Prostate Antibodies	>1 publications with PFKFB2 and Prostate
Lymph Node Antibodies	>1 publications with PFKFB2 and Lymph Node
Pancreas Antibodies	>1 publications with PFKFB2 and Pancreas
Embryonic Tissue Antibodies	>1 publications with PFKFB2 and Embryonic Tissue
Brain Antibodies	>1 publications with PFKFB2 and Brain