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RBP4 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS419718

This protein belongs to the lipocalin family and is the specific carrier for retinol (vitamin A alcohol) in the blood. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin which… More details

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Product Overview

Product Name
RBP4, Polyclonal Antibody
Full Product Name
Anti-RBP4 Antibody
Product Gene Name
anti-RBP4 antibody
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid
Purity/Purification
Affinity Purification
Concentration
1mg/ml (lot specific)
Specificity
Western blot analysis of extracts of various cell lines, using RBP4 antibody. Immunohistochemistry of paraffin-embedded mouse lung using RBP4 antibody at dilution of 1:100 (400x lens).
Preparation and Storage
Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.
Molecular Weight
23,010 Da
OMIM
X00129 mRNA
3D Structure
ModBase 3D Structure for P02753
Immunogen
Recombinant Protein of human RBP4
Storage Buffer
PBS with 0.02% sodium azide,50% glycerol, pH7.3.
Applications Tested/Suitable for anti-RBP4 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-RBP4 antibody
WB: 1:500-1:2000
IHC: 1:50-1:200

Western Blot (WB) of anti-RBP4 antibody

Rabbit Anti-RBP4 Polyclonal Antibody – Cat# MBS419718

Immunohistochemistry (IHC) of anti-RBP4 antibody

Rabbit Anti-RBP4 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS419718

Other Notes

Small volumes of anti-RBP4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RBP4 purchase

MBS419718 is an antibody targeting RBP4. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for RBP4. It may not necessarily be applicable to this product.

NCBI GI #
1021312411
NCBI GeneID
5950
NCBI Accession #
NP_001310447.1
UniProt Primary Accession #
P02753
UniProt Secondary Accession #
O43478; O43479; Q5VY24; Q8WWA3; Q9P178; D3DR38
UniProt Related Accession #
P02753
GenBank Nucleotide #
NM_001323518.1
NCBI Official Full Name
retinol-binding protein 4 isoform b
NCBI Official Synonym Full Names
retinol binding protein 4
NCBI Official Symbol
RBP4
NCBI Official Synonym Symbols
RDCCAS; MCOPCB10
UniProt Protein Name
Retinol-binding protein 4
UniProt Synonym Protein Names
Plasma retinol-binding protein; PRBP; RBP
Protein Family
Retinol-binding protein
UniProt Gene Name
RBP4
UniProt Synonym Gene Names
PRBP; RBP
NCBI Protein Information
retinol-binding protein 4

UniProt Comments for RBP4

RBP4: Delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin, this prevents its loss by filtration through the kidney glomeruli. Defects in RBP4 are a cause of retinol-binding protein deficiency (RBP deficiency). This condition causes night vision problems. It produces a typical 'fundus xerophthalmicus', featuring a progressed atrophy of the retinal pigment epithelium. Belongs to the calycin superfamily. Lipocalin family.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 10q23.33

Cellular Component: cytosol; extracellular region; extracellular space

Molecular Function: protein binding; retinol binding

Biological Process: cardiac muscle development; embryonic organ morphogenesis; embryonic retina morphogenesis in camera-type eye; embryonic skeletal development; eye development; female genitalia morphogenesis; gluconeogenesis; glucose homeostasis; heart development; lung development; maintenance of gastrointestinal epithelium; negative regulation of cardiac muscle cell proliferation; positive regulation of immunoglobulin secretion; positive regulation of insulin secretion; response to retinoic acid; retinoid metabolic process; retinol metabolic process; urinary bladder development; uterus development; vagina development

Disease: Microphthalmia, Isolated, With Coloboma 10; Retinal Dystrophy, Iris Coloboma, And Comedogenic Acne Syndrome
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Research Articles on RBP4

1. The positive association between circulating RBP4 and ApoB-containing lipoproteins in a steady metabolic state, as well as during a hypocaloric diet, appears to be attenuated in patients with very high serum triglycerides.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-RBP4 antibody

 Reference Product  PubMed Publications
 TTR antibody  >42 publications with RBP4 and TTR
 STRA6 antibody  >27 publications with RBP4 and STRA6
 ALB antibody  >4 publications with RBP4 and ALB
 RBP1 antibody  >4 publications with RBP4 and RBP1
 BCMO1 antibody  >2 publications with RBP4 and BCMO1
 ORM1 antibody  >1 publications with RBP4 and ORM1
 BCO2 antibody  >1 publications with RBP4 and BCO2
 RPE65 antibody  >1 publications with RBP4 and RPE65

Pathways associated with anti-RBP4 antibody

 Products by Pathway  Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Diseases Associated With Visual Transduction Pathway antibodies  Diseases Associated With Visual Transduction Pathway Diagram
 Diseases Of Signal Transduction Pathway antibodies  Diseases Of Signal Transduction Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Fat-soluble Vitamins Pathway antibodies  Metabolism Of Fat-soluble Vitamins Pathway Diagram
 Metabolism Of Vitamins And Cofactors Pathway antibodies  Metabolism Of Vitamins And Cofactors Pathway Diagram
 Retinoid Cycle Disease Events Pathway antibodies  Retinoid Cycle Disease Events Pathway Diagram
 Retinoid Metabolism And Transport Pathway antibodies  Retinoid Metabolism And Transport Pathway Diagram
 Retinoid Metabolism Disease Events Pathway antibodies  Retinoid Metabolism Disease Events Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram

Diseases associated with anti-RBP4 antibody

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >109 publications with RBP4 and Inflammation
 Liver Diseases Antibodies  >80 publications with RBP4 and Liver Diseases
 Fatty Liver Antibodies  >71 publications with RBP4 and Fatty Liver
 Necrosis Antibodies  >59 publications with RBP4 and Necrosis
 Hyperglycemia Antibodies  >51 publications with RBP4 and Hyperglycemia
 Glucose Intolerance Antibodies  >40 publications with RBP4 and Glucose Intolerance
 Kidney Diseases Antibodies  >40 publications with RBP4 and Kidney Diseases
 Polycystic Ovary Syndrome Antibodies  >28 publications with RBP4 and Polycystic Ovary Syndrome
 Weight Loss Antibodies  >25 publications with RBP4 and Weight Loss
 Non-alcoholic Fatty Liver Disease Antibodies  >23 publications with RBP4 and Non-alcoholic Fatty Liver Disease

Organs/Tissues associated with anti-RBP4 antibody

 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >180 publications with RBP4 and Liver
 Connective Tissue Antibodies  >130 publications with RBP4 and Connective Tissue
 Muscle Antibodies  >66 publications with RBP4 and Muscle
 Kidney Antibodies  >46 publications with RBP4 and Kidney
 Heart Antibodies  >36 publications with RBP4 and Heart
 Brain Antibodies  >20 publications with RBP4 and Brain
 Bone Antibodies  >18 publications with RBP4 and Bone
 Eye Antibodies  >16 publications with RBP4 and Eye
 Pancreas Antibodies  >16 publications with RBP4 and Pancreas
 Lung Antibodies  >12 publications with RBP4 and Lung
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