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XRCC2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS419824

This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene is involved in the repair of DNA double-strand breaks by homologous… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
XRCC2, Polyclonal Antibody
Full Product Name
Anti-XRCC2 Antibody
Product Gene Name
anti-XRCC2 antibody
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid
Purity/Purification
Affinity Purification
Concentration
1mg/ml (lot specific)
Specificity
Western blot analysis of extracts of various cell lines, using XRCC2 antibody. Immunofluorescence analysis of MCF7 cell using XRCC2 antibody. Blue: DAPI for nuclear staining.
Preparation and Storage
Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.
Molecular Weight
31,956 Da
OMIM
AF035587 mRNA
Immunogen
Recombinant protein of human XRCC2
Storage Buffer
PBS with 0.02% sodium azide,50% glycerol, pH7.3.
Applications Tested/Suitable for anti-XRCC2 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes for anti-XRCC2 antibody
WB: 1:500 - 1:2000
IHC: 1:50- 1:200
IF: 1:50- 1:200

Western Blot (WB) of anti-XRCC2 antibody

Rabbit Anti-XRCC2 Polyclonal Antibody – Cat# MBS419824

Immunofluorescence (IF) of anti-XRCC2 antibody

Rabbit Anti-XRCC2 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS419824

Other Notes

Small volumes of anti-XRCC2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for XRCC2 purchase

MBS419824 is an antibody targeting XRCC2. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for XRCC2. It may not necessarily be applicable to this product.

NCBI GI #
3288461
NCBI GeneID
7516
NCBI Accession #
CAA70065.1
UniProt Secondary Accession #
B2R925
UniProt Related Accession #
O43543
NCBI Official Full Name
XRCC2
NCBI Official Synonym Full Names
X-ray repair cross complementing 2
NCBI Official Symbol
XRCC2
NCBI Official Synonym Symbols
FANCU
UniProt Protein Name
DNA repair protein XRCC2
UniProt Synonym Protein Names
X-ray repair cross-complementing protein 2
Protein Family
DNA repair protein
UniProt Gene Name
XRCC2
NCBI Protein Information
DNA repair protein XRCC2

UniProt Comments for XRCC2

XRCC2: Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions. The BCDX2 complex binds single-stranded DNA, single-stranded gaps in duplex DNA and specifically to nicks in duplex DNA. Belongs to the RecA family. RAD51 subfamily.

Chromosomal Location of Human Ortholog: 7q36.1

Cellular Component: centrosome; nucleoplasm; replication fork

Molecular Function: DNA-dependent ATPase activity; double-stranded DNA binding; endodeoxyribonuclease activity; four-way junction DNA binding; protein binding; recombinase activity; single-stranded DNA binding

Biological Process: centrosome organization and biogenesis; DNA repair; DNA synthesis during DNA repair; double-strand break repair via homologous recombination; meiosis; meiotic DNA recombinase assembly; meiotic recombination; mitotic cell cycle; mitotic recombination; response to ionizing radiation; strand displacement; strand invasion

Disease: Fanconi Anemia, Complementation Group U
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Research Articles on XRCC2

1. Polymorphism of XRCC2 gene is associated with Nasopharyngeal Carcinoma.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-XRCC2 antibody

 Reference Product  PubMed Publications
 RAD51D antibody  >49 publications with XRCC2 and RAD51D

Pathways associated with anti-XRCC2 antibody

 Products by Pathway  Pathway Diagram
 Homologous Recombination Pathway antibodies  Homologous Recombination Pathway Diagram
 Homologous Recombination Pathway antibodies  Homologous Recombination Pathway Diagram

Diseases associated with anti-XRCC2 antibody

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >64 publications with XRCC2 and Neoplasms
 Skin Diseases Antibodies  >25 publications with XRCC2 and Skin Diseases
 Breast Neoplasms Antibodies  >24 publications with XRCC2 and Breast Neoplasms
 Carcinoma Antibodies  >13 publications with XRCC2 and Carcinoma
 Adenocarcinoma Antibodies  >12 publications with XRCC2 and Adenocarcinoma
 Genital Neoplasms, Female Antibodies  >9 publications with XRCC2 and Genital Neoplasms, Female
 Gonadal Disorders Antibodies  >7 publications with XRCC2 and Gonadal Disorders
 Ovarian Neoplasms Antibodies  >7 publications with XRCC2 and Ovarian Neoplasms
 Drug Toxicity Antibodies  >7 publications with XRCC2 and Drug Toxicity
 Sarcoma Antibodies  >4 publications with XRCC2 and Sarcoma

Organs/Tissues associated with anti-XRCC2 antibody

 Organ/Tissue Name  Pubmed Publications
 Testis Antibodies  >5 publications with XRCC2 and Testis
 Brain Antibodies  >3 publications with XRCC2 and Brain
 Embryonic Tissue Antibodies  >3 publications with XRCC2 and Embryonic Tissue
 Mouth Antibodies  >2 publications with XRCC2 and Mouth
 Lymph Node Antibodies  >1 publications with XRCC2 and Lymph Node
 Liver Antibodies  >1 publications with XRCC2 and Liver
 Mammary Gland Antibodies  >1 publications with XRCC2 and Mammary Gland
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