Rabbit Anti-APCS Polyclonal Antibody – Cat# MBS419927

APCS Antibody – Rabbit Polyclonal

Name: APCS Antibody; Polyclonal; Rabbit; Human/Mouse-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS419927
Price: 475 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS419927

The protein encoded by this gene is a glycoprotein, belonging to the pentraxin family of proteins, which has a characteristic pentameric organization. These family members have considerable sequence homology which is thought to be the result of gene… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

APCS, Polyclonal Antibody

Full Product Name

Anti-APCS Antibody

Product Gene Name

anti-APCS antibody

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human, Mouse

Form/Format

Liquid

Purity/Purification

Affinity Purification

Concentration

1mg/ml (lot specific)

Specificity

Western blot analysis of extracts of various cell lines, using APCS antibody.

Preparation and Storage

Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.

Molecular Weight

25,387 Da

OMIM

D00097 Genomic DNA

Immunogen

Recombinant protein of human APCS

Storage Buffer

PBS with 0.02% sodium azide,50% glycerol, pH7.3.

Applications Tested/Suitable for anti-APCS antibody

Western Blot (WB), Immunohistochemistry (IHC)

Application Notes for anti-APCS antibody

WB: 1:500 - 1:2000
IHC: 1:50- 1:200

Other Notes

Small volumes of anti-APCS antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for APCS purchase

MBS419927 is an antibody targeting APCS. Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for APCS. It may not necessarily be applicable to this product.

NCBI GI #

47496573

NCBI GeneID

325

NCBI Accession #

CAG29309.1

UniProt Related Accession #

P02743

NCBI Official Full Name

APCS, partial

NCBI Official Synonym Full Names

amyloid P component, serum

NCBI Official Symbol

APCS

NCBI Official Synonym Symbols

SAP; PTX2; HEL-S-92n

UniProt Protein Name

Serum amyloid P-component

UniProt Synonym Protein Names

9.5S alpha-1-glycoprotein

UniProt Gene Name

APCS

UniProt Synonym Gene Names

PTX2; SAP

NCBI Protein Information

serum amyloid P-component

UniProt Comments for APCS

APCS: Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. May also function as a calcium-dependent lectin. SAP is a precursor of amyloid component P which is found in basement membrane and associated with amyloid deposits. Belongs to the pentaxin family.

Protein type: Chaperone; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 1q23.2

Cellular Component: extracellular matrix; extracellular region; extracellular space; nucleus

Molecular Function: calcium ion binding; complement component C1q binding; unfolded protein binding; virion binding

Biological Process: acute-phase response; cellular protein metabolic process; chaperone-mediated protein complex assembly; innate immune response; negative regulation of acute inflammatory response; negative regulation of monocyte differentiation; negative regulation of viral reproduction; negative regulation of virion penetration into host cell; protein folding

Research Articles on APCS

1. SNPs in APCS were associated with late age at onset in familial amyloid polyneuropathy.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-APCS antibody

Reference Product	PubMed Publications
TTR antibody	>2 publications with APCS and TTR
GSN antibody	>1 publications with APCS and GSN
FGA antibody	>1 publications with APCS and FGA

Pathways associated with anti-APCS antibody

Products by Pathway	Pathway Diagram
Amyloids Pathway antibodies	Amyloids Pathway Diagram
Disease Pathway antibodies	Disease Pathway Diagram

Diseases associated with anti-APCS antibody

Disease Name	Pubmed Publications
Cardiovascular Diseases Antibodies	>1766 publications with APCS and Cardiovascular Diseases
Heart Diseases Antibodies	>1725 publications with APCS and Heart Diseases
Immune System Diseases Antibodies	>911 publications with APCS and Immune System Diseases
Inflammation Antibodies	>443 publications with APCS and Inflammation
Necrosis Antibodies	>250 publications with APCS and Necrosis
Brain Diseases Antibodies	>187 publications with APCS and Brain Diseases
Congenital Abnormalities Antibodies	>181 publications with APCS and Congenital Abnormalities
Heart Failure Antibodies	>148 publications with APCS and Heart Failure
Lung Diseases Antibodies	>135 publications with APCS and Lung Diseases
Coronary Artery Disease Antibodies	>129 publications with APCS and Coronary Artery Disease

Organs/Tissues associated with anti-APCS antibody

Organ/Tissue Name	Pubmed Publications
Bone Antibodies	>483 publications with APCS and Bone
Lung Antibodies	>213 publications with APCS and Lung
Liver Antibodies	>154 publications with APCS and Liver
Muscle Antibodies	>112 publications with APCS and Muscle
Pancreas Antibodies	>62 publications with APCS and Pancreas
Uncharacterized Tissue Antibodies	>2 publications with APCS and Uncharacterized Tissue