Goat Anti-MARK1 Polyclonal Antibody – Cat# MBS420009

MARK1 Antibody – Goat Polyclonal

Name: MARK1 Antibody; Polyclonal; Goat; Mouse-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS420009
Price: 305 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS420009

MBS420009 is an antibody targeting MARK1. Also known as Goat anti-Mark1 (mouse) Antibody. Reactive in Expected from sequence similarity: Mouse, Rat. Host: Goat. More details

$305 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Mark1, Polyclonal Antibody

Full Product Name

Goat anti-Mark1 (mouse) Antibody

Product Gene Name

anti-MARK1 antibody

Product Synonym Names

Mark1; MAP/microtubule affinity-regulating kinase 1; AW491150; B930025N23Rik; Emk3; KIAA1477; mKIAA1477; Mark1 antibody; MAP/microtubule affinity-regulating kinase 1 antibody; AW491150 antibody; B930025N23Rik antibody; Emk3 antibody; KIAA1477 antibody; mKIAA1477 antibody; Mark1 (mouse)

Immunogen Sequence

EQKEEWDKDT ARR

Clonality

Polyclonal

Host

Goat

Species Reactivity

Expected from sequence similarity: Mouse, Rat

Form/Format

Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Purity/Purification

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Concentration

100ug specific antibody in 200ul (lot specific)

Preparation and Storage

Aliquot and store at -20 degree C. Minimize freezing and thawing.

Antibody/Peptide Pairs

Mark1 peptide (MBS426871) is used for blocking the activity of Mark1 antibody (MBS420009)

Molecular Weight

88,335 Da

Immunogen

Peptide with sequence C-EQKEEWDKDTARR, from the internal region of the protein sequence according to NP_663490.1.

Epitope

Internal region

ISO Certification

Manufactured in an ISO 9001:2008 Certified Laboratory.

Applications Tested/Suitable for anti-MARK1 antibody

Peptide ELISA (EIA)

Application Notes for anti-MARK1 antibody

Peptide ELISA: Antibody detection limit dilution 1: 1000.
Western Blot: Preliminary experiments in Brain and Testis lysates from Mouse and Rat gave no specific signal but low background (at antibody concentration up to 1ug/ml).

Other Notes

Small volumes of anti-MARK1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for MARK1. It may not necessarily be applicable to this product.

NCBI GI #

21704014

NCBI GeneID

226778

NCBI Accession #

NP_663490.1

UniProt Secondary Accession #

Q69ZI7; E9QL17

UniProt Related Accession #

Q8VHJ5

GenBank Nucleotide #

NM_145515.1

NCBI Official Full Name

MAP/microtubule affinity-regulating kinase 1

NCBI Official Synonym Full Names

MAP/microtubule affinity regulating kinase 1

NCBI Official Symbol

Mark1

NCBI Official Synonym Symbols

Emk3; Par-1c; mPar-1c; AW491150; mKIAA1477; B930025N23Rik

UniProt Protein Name

Serine/threonine-protein kinase MARK1

UniProt Synonym Protein Names

ELKL motif serine/threonine-protein kinase 3; MAP/microtubule affinity-regulating kinase 1; PAR1 homolog c; Par-1c; mPar-1c

Protein Family

Serine/threonine-protein kinase

UniProt Gene Name

Mark1

UniProt Synonym Gene Names

Par-1c; mPar-1c

UniProt Entry Name

MARK1_MOUSE

NCBI Protein Information

serine/threonine-protein kinase MARK1

UniProt Comments for MARK1

MARK1: a member of the CAMKL family of protein kinases. The MARK group of kinases is apparently involved in the control of cell polarity, microtubule stability and cancer. MARK1 forms a tight association with Tau in neurofibrillary tangles in Alzheimer disease tissue.

Protein type: Protein kinase, CAMK; Protein kinase, Ser/Thr (non-receptor); Kinase, protein; EC 2.7.11.1; EC 2.7.11.26; CAMK group; CAMKL family; MARK subfamily

Cellular Component: cytoplasm; cytoskeleton; membrane; plasma membrane

Molecular Function: ATP binding; kinase activity; lipid binding; magnesium ion binding; metal ion binding; nucleotide binding; phosphatidylinositol-4,5-bisphosphate binding; phosphatidylserine binding; protein kinase activity; protein serine/threonine kinase activity; tau-protein kinase activity; transferase activity

Biological Process: cytoskeleton organization and biogenesis; microtubule cytoskeleton organization and biogenesis; neuron migration; phosphorylation; protein amino acid phosphorylation; Wnt receptor signaling pathway

Research Articles on MARK1

1. In vitro kinase assays and metabolic-labeling experiments in living cells confirmed MARK1 as an LRRK2 substrate. Moreover, we also showed that LRRK2 and MARK1 are interacting in eukaryotic cells.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-MARK1 antibody

Reference Product	PubMed Publications
Mark2 antibody	>28 publications with MARK1 and Mark2
Mtap2 antibody	>1 publications with MARK1 and Mtap2
Mapt antibody	>1 publications with MARK1 and Mapt

Diseases associated with anti-MARK1 antibody

Disease Name	Pubmed Publications
Nervous System Diseases Antibodies	>19 publications with MARK1 and Nervous System Diseases
Liver Diseases Antibodies	>3 publications with MARK1 and Liver Diseases
Inflammation Antibodies	>3 publications with MARK1 and Inflammation
Stomach Neoplasms Antibodies	>3 publications with MARK1 and Stomach Neoplasms
Necrosis Antibodies	>2 publications with MARK1 and Necrosis
Cardiovascular Diseases Antibodies	>2 publications with MARK1 and Cardiovascular Diseases
Lung Neoplasms Antibodies	>2 publications with MARK1 and Lung Neoplasms
Precancerous Conditions Antibodies	>1 publications with MARK1 and Precancerous Conditions
Cognition Disorders Antibodies	>1 publications with MARK1 and Cognition Disorders
Disease Models, Animal Antibodies	>1 publications with MARK1 and Disease Models, Animal

Organs/Tissues associated with anti-MARK1 antibody

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>27 publications with MARK1 and Brain
Liver Antibodies	>10 publications with MARK1 and Liver
Lung Antibodies	>5 publications with MARK1 and Lung
Ovary Antibodies	>2 publications with MARK1 and Ovary
Skin Antibodies	>2 publications with MARK1 and Skin
Embryonic Tissue Antibodies	>2 publications with MARK1 and Embryonic Tissue
Testis Antibodies	>1 publications with MARK1 and Testis
Adipose Tissue Antibodies	>1 publications with MARK1 and Adipose Tissue
Spinal Cord Antibodies	>1 publications with MARK1 and Spinal Cord
Eye Antibodies	>1 publications with MARK1 and Eye