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OSBPL2 Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS420292

MBS420292 is an antibody targeting OSBPL2. Also known as Goat anti-ORP2 Antibody. Reactive in Tested: Human; Expected from sequence similarity: Human, Mouse, Rat. Host: Goat. More details

$450 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ORP2 (OSBPL2), Polyclonal Antibody
Full Product Name
Goat anti-ORP2 Antibody
Product Gene Name
Product Synonym Gene Name
ORP2
Product Synonym Names
OSBPL2; ORP2; ORP-2; MGC4307; MGC8342; FLJ20223; KIAA0772; oxysterol binding protein-like 2; OSBP-related protein 2; oxysterol-binding protein-related protein 2; oxysterol-binding protein-like protein 2; OSBPL2 antibody; ORP2 antibody; ORP-2 antibody; MGC4307 antibody; MGC8342 antibody; FLJ20223 antibody; KIAA0772 antibody; oxysterol binding protein-like 2 antibody; OSBP-related protein 2 antibody; oxysterol-binding protein-related protein 2 antibody; oxysterol-binding protein-like protein 2 antibody
Immunogen Sequence
YFERNFSDCP DIY
Clonality
Polyclonal
Host
Goat
Species Reactivity
Tested: Human; Expected from sequence similarity: Human, Mouse, Rat
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration
100ug specific antibody in 200ul (lot specific)
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.
Antibody/Peptide Pairs
ORP2 peptide (MBS425565) is used for blocking the activity of ORP2 antibody (MBS420292)
Molecular Weight
53,971 Da
OMIM
606731
Immunogen
Peptide with sequence YFERNFSDCPDIY, from the C Terminus of the protein sequence according to NP_055650.1; NP_653081.1.
Epitope
C Terminus
Note
This antibody is expected to recognise both reported isoforms (represented by NP_055650.1 and NP_653081.1)
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Applications Tested/Suitable for anti-OSBPL2 antibody
Peptide ELISA (EIA), Western Blot (WB)
Application Notes for anti-OSBPL2 antibody
Peptide ELISA: Antibody detection limit dilution 1: 8000.
Western Blot: Approx 55-60kDa band observed in Human Heart lysates (predicted MWs of 54 and 55kDa according to NP_055650.1 and NP_653081.1). Recommended for use at 1-2ug/ml.

Western Blot (WB) of anti-OSBPL2 antibody

Staining (1.5ug/ml) of Human Heart lysate (RIPA buffer, 30ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.
Goat Anti-OSBPL2 Polyclonal Antibody – Cat# MBS420292

Other Notes

Small volumes of anti-OSBPL2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for OSBPL2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI Related Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
oxysterol-binding protein-related protein 2 isoform 1
NCBI Official Synonym Full Names
oxysterol binding protein like 2
NCBI Official Symbol
OSBPL2
NCBI Official Synonym Symbols
ORP2; ORP-2; DFNA67; DNFA67
UniProt Protein Name
Oxysterol-binding protein-related protein 2
UniProt Gene Name
OSBPL2
UniProt Synonym Gene Names
KIAA0772; ORP2; ORP-2; OSBP-related protein 2
UniProt Entry Name
OSBL2_HUMAN
NCBI Protein Information
oxysterol-binding protein-related protein 2

NCBI Summary for OSBPL2

This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although the encoded protein contains only the sterol-binding domain. In vitro studies have shown that the encoded protein can bind strongly to phosphatic acid and weakly to phosphatidylinositol 3-phosphate, but cannot bind to 25-hydroxycholesterol. The protein associates with the Golgi apparatus. Transcript variants encoding different isoforms have been described. [provided by RefSeq, Sep 2014]
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UniProt Comments for OSBPL2

OSBPL2: Binds phospholipids; exhibits strong binding to phosphatidic acid and weak binding to phosphatidylinositol 3- phosphate. Belongs to the OSBP family. 2 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 20q13.33

Molecular Function: cholesterol binding; protein binding

Biological Process: lipid transport

Disease: Deafness, Autosomal Dominant 67
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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