Goat Anti-FBXL6 Polyclonal Antibody – Cat# MBS420325

FBXL6 Antibody – Goat Polyclonal

Name: FBXL6 Antibody; Polyclonal; Goat; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS420325
Price: 310 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS420325

MBS420325 is an antibody targeting FBXL6. Also known as Goat anti-FBXL6 Antibody. Reactive in Expected from sequence similarity: Human, Mouse. Host: Goat. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

FBXL6, Polyclonal Antibody

Full Product Name

Goat anti-FBXL6 Antibody

Product Gene Name

anti-FBXL6 antibody

Product Synonym Names

FBXL6; F-box and leucine-rich repeat protein 6; FBL6; FLJ22888; F-box protein Fbl6; FBL6A; PP14630; FBXL6 antibody; F-box and leucine-rich repeat protein 6 antibody; FBL6 antibody; FLJ22888 antibody; F-box protein Fbl6 antibody; FBL6A antibody; PP14630 antibody

Immunogen Sequence

CLEQLLTSPS PS

Clonality

Polyclonal

Host

Goat

Species Reactivity

Expected from sequence similarity: Human, Mouse

Form/Format

Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Purity/Purification

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Concentration

100ug specific antibody in 200ul (lot specific)

Preparation and Storage

Aliquot and store at -20 degree C. Minimize freezing and thawing.

Molecular Weight

57,914 Da

OMIM

609076

Immunogen

Peptide with sequence CLEQLLTSPSPS, from the C Terminus of the protein sequence according to NP_036294.1; NP_078831.3.

Epitope

C Terminus

Note

This is expected to recognise reported human isoforms (NP_036294.1 and NP_078831.3).

ISO Certification

Manufactured in an ISO 9001:2008 Certified Laboratory.

Applications Tested/Suitable for anti-FBXL6 antibody

Peptide ELISA (EIA)

Application Notes for anti-FBXL6 antibody

Peptide ELISA: Antibody detection limit dilution 1: 8000.
Western Blot: No signal obtained yet but low background observed in Human Kidney and Heart extracts at up to 1ug/ml.

Other Notes

Small volumes of anti-FBXL6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for FBXL6. It may not necessarily be applicable to this product.

NCBI GI #

16306576

NCBI GeneID

26233

NCBI Accession #

NP_036294.1

NCBI Related Accession #

NP_078831.3

UniProt Secondary Accession #

Q53G43; Q9H5W9; Q9UKC7

UniProt Related Accession #

Q8N531

GenBank Nucleotide #

NM_012162.2

NCBI Official Full Name

F-box/LRR-repeat protein 6 isoform 1

NCBI Official Synonym Full Names

F-box and leucine-rich repeat protein 6

NCBI Official Symbol

FBXL6

NCBI Official Synonym Symbols

FBL6; FBL6A; PP14630

UniProt Protein Name

F-box/LRR-repeat protein 6

UniProt Synonym Protein Names

F-box and leucine-rich repeat protein 6; F-box protein FBL6; FBL6A

Protein Family

F-box/LRR-repeat protein

UniProt Gene Name

FBXL6

UniProt Synonym Gene Names

FBL6

UniProt Entry Name

FBXL6_HUMAN

NCBI Protein Information

F-box/LRR-repeat protein 6

NCBI Summary for FBXL6

This gene encodes a member of a family of proteins that are characterized by an F-box motif. The encoded protein also contains leucine-rich repeats. F-box-containing proteins comprise one of the subunits of the SCF (SKP1-cullin-F-box) complex, which functions in phosphorylation-dependent ubiquitination. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

UniProt Comments for FBXL6

FBXL6: Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Ligase; Ubiquitin conjugating system

Chromosomal Location of Human Ortholog: 8q24.3

Molecular Function: ubiquitin-protein ligase activity

Biological Process: protein ubiquitination; proteolysis

Research Articles on FBXL6

1. Fbl6 regulates Tel/Yan protein stability and allows appropriate spatiotemporal control of gene expression by these repressors.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.