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Tensin 1/TNS1 (TNS1) Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS420337

MBS420337 is an antibody targeting TNS1. Also known as Goat anti-Tensin 1/TNS1 Antibody. Reactive in Expected from sequence similarity: Human, Mouse, Rat, Dog, Cow. Host: Goat. More details

$450 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Tensin 1/TNS1, Polyclonal Antibody
Full Product Name
Goat anti-Tensin 1/TNS1 Antibody
Product Gene Name
Product Synonym Names
Goat Anti-Tensin 1 (aa902-914) Antibody; TNS1; tensin 1; TNS; tensin; MGC88584; PRO0929; FLJ10923; DKFZP434G162; MSTP091; DKFZp586K0617; MST091; MST122; MST127; MSTP122; MSTP127; MXRA6; Matrix-remodelling-associated protein 6; matrix-remodelling associated 6; tensin; TNS1 antibody; tensin 1 antibody; TNS antibody; tensin antibody; MGC88584 antibody; PRO0929 antibody; FLJ10923 antibody; DKFZP434G162 antibody; MSTP091 antibody; DKFZp586K0617 antibody; MST091 antibody; MST122 antibody; MST127 antibody; MSTP122 antibody; MSTP127 antibody; MXRA6 antibody; Matrix-remodelling-associated protein 6 antibody; matrix-remodelling associated 6 antibody; tensin antibody; Tensin 1; Tensin 1 / TNS1
Immunogen Sequence
C-VSKVMLNA GQKR
Clonality
Polyclonal
Host
Goat
Species Reactivity
Expected from sequence similarity: Human, Mouse, Rat, Dog, Cow
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH 7.3 with 0.5% bovine serum albumin.
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.
Antibody/Peptide Pairs
OMIM
600076
Immunogen
Peptide with sequence C-VSKVMLNAGQKR, from the C Terminus of the protein sequence according to NP_072174.3.
Epitope
C Terminus
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Applications Tested/Suitable for anti-TNS1 antibody
Peptide ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB)
Application Notes for anti-TNS1 antibody
Peptide ELISA:
Antibody detection limit dilution 1:2000.

Immunohistochemistry:
In paraffin embedded Human Kidney shows weak staining of the basement membranes of convoluted tubules. Recommended concentration, 4-6ug/ml.

Western Blot:
Preliminary experiments in Human Heart, Kidney and Skeletal Muscle lysates gave no specific signal but low background (at antibody concentration up to 1ug/ml).

Immunohistochemistry (IHC) of anti-TNS1 antibody

(4ug/ml) staining of paraffin embedded Human Kidney. Steamed antigen retrieval with Tris/EDTA buffer pH 9, HRP-staining.
Goat Anti-TNS1 Polyclonal Antibody – Cat# MBS420337

Other Notes

Small volumes of anti-TNS1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for TNS1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
tensin-1 isoform 1
NCBI Official Synonym Full Names
tensin 1
NCBI Official Symbol
TNS1
NCBI Official Synonym Symbols
TNS; MXRA6; MST091; MST122; MST127; MSTP091; MSTP122; MSTP127; PPP1R155
UniProt Protein Name
Tensin-1
Protein Family
UniProt Gene Name
TNS1
UniProt Synonym Gene Names
TNS
UniProt Entry Name
TENS1_HUMAN
NCBI Protein Information
tensin-1

NCBI Summary for TNS1

The protein encoded by this gene localizes to focal adhesions, regions of the plasma membrane where the cell attaches to the extracellular matrix. This protein crosslinks actin filaments and contains a Src homology 2 (SH2) domain, which is often found in molecules involved in signal transduction. This protein is a substrate of calpain II. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015]
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UniProt Comments for TNS1

tensin 1: May be involved in cell migration, cartilage development and in linking signal transduction pathways to the cytoskeleton.

Protein type: Adaptor/scaffold; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 2q35-q36

Cellular Component: cell surface; cytoplasm; cytoskeleton; focal adhesion

Molecular Function: actin binding; protein binding

Biological Process: cell-substrate junction assembly
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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