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P8/NUPR1 (NUPR1) Antibody – Goat

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS420484

MBS420484 is an antibody targeting NUPR1. Also known as Goat anti-P8/NUPR1 Antibody. Reactive in Expected from sequence similarity: Human. Host: Goat. More details

$305 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
P8/NUPR1, Antibody
Full Product Name
Goat anti-P8/NUPR1 Antibody
Product Gene Name
anti-NUPR1 antibody
Product Synonym Gene Name
P8
Product Synonym Names
NUPR1, Nuclear Protein 1, P8, COM1, p8 protein (candidate of metastasis 1), p8 protein, nuclear protein, transcriptional regulator, 1, candidate of metastasis 1
Immunogen Sequence
ATFPPATSAP QQP
Host
Goat
Species Reactivity
Expected from sequence similarity: Human
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.
Antibody/Peptide Pairs
P8 / NUPR1 peptide (MBS425423) is used for blocking the activity of P8/NUPR1 antibody (MBS420484)
OMIM
614812
Immunogen
Peptide with sequence ATFPPATSAPQQP-C, from the N Terminus of the protein sequence according to NP_001035948.1; NP_036517.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Applications Tested/Suitable for anti-NUPR1 antibody
Peptide ELISA (EIA)
Application Notes for anti-NUPR1 antibody
Peptide ELISA: Antibody detection limit dilution 1: 32000.
Western Blot: Preliminary experiments gave no signal but low background in HepG2 and Human Pancreas extracts at up to 1ug/ml. Please note that we would not expect our routine western blot protocol to reliably detect proteins as small as the predicted size of this protein (approx 9kDa according to NP_036517).

Other Notes

Small volumes of anti-NUPR1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for NUPR1. It may not necessarily be applicable to this product.

NCBI GI #
109948307
NCBI GeneID
26471
NCBI Accession #
NP_001035948.1
NCBI Related Accession #
NP_036517
UniProt Secondary Accession #
O60357; Q6FGG3; B2R5C4
UniProt Related Accession #
O60356
GenBank Nucleotide #
NM_001042483.1
NCBI Official Full Name
nuclear protein 1 isoform a
NCBI Official Synonym Full Names
nuclear protein 1, transcriptional regulator
NCBI Official Symbol
NUPR1
NCBI Official Synonym Symbols
P8; COM1
UniProt Protein Name
Nuclear protein 1
UniProt Synonym Protein Names
Candidate of metastasis 1; Nuclear transcriptional regulator protein 1
Protein Family
Nuclear protein
UniProt Gene Name
NUPR1
UniProt Entry Name
NUPR1_HUMAN
NCBI Protein Information
nuclear protein 1

UniProt Comments for NUPR1

NUPR1: Could participate in the response to proapoptotic stimuli and promotes cellular growth in a way that helps the tissue counteract diverse injuries. May contribute to the metastatic phenotype. Belongs to the NUPR family.

Protein type: Cell development/differentiation; Cell cycle regulation; Apoptosis

Chromosomal Location of Human Ortholog: 16p11.2

Cellular Component: cytoplasm; nucleus

Molecular Function: chromatin binding; DNA binding

Biological Process: acute inflammatory response; cell growth; DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis; male gonad development; negative regulation of cell cycle; negative regulation of fibroblast proliferation; positive regulation of apoptosis; positive regulation of protein modification process; protein amino acid acetylation; protein complex assembly; regulation of transcription from RNA polymerase II promoter; response to toxin; transcription, DNA-dependent
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Research Articles on NUPR1

1. Hepatitis B virus X (HBx) protein can modulate NUPR1 expression through the Smad4 pathway and NUPR1 has a role in hepatocellular carcinoma progression.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-NUPR1 antibody

 Products by Pathway  Pathway Diagram
 Transcriptional Misregulation In Cancer Pathway antibodies  Transcriptional Misregulation In Cancer Pathway Diagram
 Transcriptional Misregulation In Cancer Pathway antibodies  Transcriptional Misregulation In Cancer Pathway Diagram

Diseases associated with anti-NUPR1 antibody

 Disease Name  Pubmed Publications
 Pancreatitis Antibodies  >15 publications with NUPR1 and Pancreatitis
 Disease Models, Animal Antibodies  >11 publications with NUPR1 and Disease Models, Animal
 Breast Neoplasms Antibodies  >10 publications with NUPR1 and Breast Neoplasms
 Inflammation Antibodies  >7 publications with NUPR1 and Inflammation
 Cell Transformation, Neoplastic Antibodies  >7 publications with NUPR1 and Cell Transformation, Neoplastic
 Neoplasms, Experimental Antibodies  >7 publications with NUPR1 and Neoplasms, Experimental
 Hypertrophy Antibodies  >6 publications with NUPR1 and Hypertrophy
 Necrosis Antibodies  >5 publications with NUPR1 and Necrosis
 Lung Neoplasms Antibodies  >4 publications with NUPR1 and Lung Neoplasms
 Carcinoma, Hepatocellular Antibodies  >4 publications with NUPR1 and Carcinoma, Hepatocellular

Organs/Tissues associated with anti-NUPR1 antibody

 Organ/Tissue Name  Pubmed Publications
 Pancreas Antibodies  >21 publications with NUPR1 and Pancreas
 Liver Antibodies  >9 publications with NUPR1 and Liver
 Lung Antibodies  >8 publications with NUPR1 and Lung
 Brain Antibodies  >5 publications with NUPR1 and Brain
 Nerve Antibodies  >4 publications with NUPR1 and Nerve
 Muscle Antibodies  >4 publications with NUPR1 and Muscle
 Heart Antibodies  >3 publications with NUPR1 and Heart
 Eye Antibodies  >3 publications with NUPR1 and Eye
 Embryonic Tissue Antibodies  >3 publications with NUPR1 and Embryonic Tissue
 Kidney Antibodies  >3 publications with NUPR1 and Kidney
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