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CDEP/FARP1 (FARP1) Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS420617

MBS420617 is an antibody targeting FARP1. Also known as Goat anti-CDEP/FARP1 Antibody. Reactive in Expected from sequence similarity: Human, Mouse, Rat, Cow. Host: Goat. More details

$450 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CDEP/FARP1, Polyclonal Antibody
Full Product Name
Goat anti-CDEP/FARP1 Antibody
Product Gene Name
Product Synonym Gene Name
CDEP
Product Synonym Names
FARP1; FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived); CDEP; chondrocyte-derived ezrin-like protein; RP11-111L24.1; MGC87400; PLEKH2; FERM, RhoGEF, and pleckstrin domain protein 1; FARP1 antibody; FERM; RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) antibody; CDEP antibody; chondrocyte-derived ezrin-like protein antibody; RP11-111L24.1 antibody; MGC87400 antibody; PLEKH2 antibody; FERM; RhoGEF; and pleckstrin domain protein 1 antibody; CDEP / FARP1
Immunogen Sequence
GEIEQRPTPG SRL
Clonality
Polyclonal
Host
Goat
Species Reactivity
Expected from sequence similarity: Human, Mouse, Rat, Cow
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration
100ug specific antibody in 200ul (lot specific)
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.
Antibody/Peptide Pairs
Molecular Weight
14,138 Da
OMIM
602654
Immunogen
Peptide with sequence GEIEQRPTPGSRL-C, from the N Terminus of the protein sequence according to NP_005757.1; NP_001001715.2.
Epitope
N Terminus
Note
This antibody is expected to recognise isoform 1 (NP_005757.1) and isoform 2 (NP_001001715.2).
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Applications Tested/Suitable for anti-FARP1 antibody
Peptide ELISA (EIA)
Application Notes for anti-FARP1 antibody
Peptide ELISA: Antibody detection limit dilution 1: 32000.
Western Blot: Preliminary experiments in Human Liver, Kidney and Lung lysates gave no specific signal but low background (at antibody concentration up to 1ug/ml).

Other Notes

Small volumes of anti-FARP1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for FARP1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI Related Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
FERM, RhoGEF and pleckstrin domain-containing protein 1 isoform 1
NCBI Official Synonym Full Names
FERM, ARH/RhoGEF and pleckstrin domain protein 1
NCBI Official Symbol
FARP1
NCBI Official Synonym Symbols
CDEP; PLEKHC2; PPP1R75; FARP1-IT1
UniProt Protein Name
FERM, RhoGEF and pleckstrin domain-containing protein 1
UniProt Synonym Protein Names
Chondrocyte-derived ezrin-like protein; Pleckstrin homology domain-containing family C member 2; PH domain-containing family C member 2
UniProt Gene Name
FARP1
UniProt Synonym Gene Names
CDEP; PLEKHC2; PH domain-containing family C member 2
UniProt Entry Name
FARP1_HUMAN
NCBI Protein Information
FERM, RhoGEF and pleckstrin domain-containing protein 1

NCBI Summary for FARP1

This gene encodes a protein containing a FERM (4.2, exrin, radixin, moesin) domain, a Dbl homology domain, and two pleckstrin homology domains. These domains are found in guanine nucleotide exchange factors and proteins that link the cytoskeleton to the cell membrane. The encoded protein functions in neurons to promote dendritic growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2013]
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UniProt Comments for FARP1

FARP1: May function as Rho-guanine nucleotide exchange factor. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: GEFs; Motility/polarity/chemotaxis; GEFs, Rac/Rho

Chromosomal Location of Human Ortholog: 13q32.2

Cellular Component: cell junction; cytoplasm; cytoskeleton; cytosol; dendrite; dendritic spine; extrinsic to internal side of plasma membrane; filopodium

Molecular Function: cytoskeletal protein binding; Rac guanyl-nucleotide exchange factor activity; Rho guanyl-nucleotide exchange factor activity

Biological Process: dendrite morphogenesis; positive regulation of GTPase activity; regulation of Rho protein signal transduction; synaptogenesis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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