Sex Hormone Binding Globulin (SHBG) ELISA Kit for Rabbit

Name: Rabbit SHBG ELISA Kit; Sex Hormone Binding Globulin; MyBioSource
Brand: MyBioSource
SKU: MBS042066
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS042066

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only! This kit is intended to be used for determination the level of SHBG (hereafter termed "analyte") in undiluted original Rabbit body fluids, tissue… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

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Product Overview

Online Datasheet in PDF

Product Name

Sex Hormone Binding Globulin (SHBG), ELISA Kit

Full Product Name

Rabbit Sex Hormone Binding Globulin ELISA Kit

Product Gene Name

SHBG elisa kit

Species Reactivity

Rabbit

Assay Type

Quantitative Sandwich

Samples

Body fluids, tissue homogenates, secretions or feces samples

Detection Range

6.25nmol/L-200nmol/L

Sensitivity

1.0nmol/L.

Specificity

No significant cross-reactivity or interference between this analyte and analogues is observed.

Preparation and Storage

Store all reagents at 2-8 degree C

Inter-assay Precision

Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

Intra-assay Precision

Intra-assay CV (%) is less than 15%

Molecular Weight

43,779 Da

Chromosome Location

Chromosome: 17; NC_000017.10 (7517382..7536700). Location: 17p13-p12

OMIM

182205

3D Structure

ModBase 3D Structure for P04278

Other Notes

Small volumes of SHBG elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SHBG purchase

MBS042066 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Sex Hormone Binding Globulin (SHBG) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing SHBG. The ELISA analytical biochemical technique of the MBS042066 kit is based on SHBG antibody-SHBG antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect SHBG antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, SHBG. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for SHBG. It may not necessarily be applicable to this product.

NCBI GI #

7382460

NCBI GeneID

6462

NCBI Accession #

NP_001031.2

UniProt Primary Accession #

P04278

UniProt Secondary Accession #

P14689; Q16616; Q3MIL0; Q6ISD2; B0FWH4; E9PGW1; F5H5Z8; I3L1N7

UniProt Related Accession #

P04278

GenBank Nucleotide #

NM_001040.3

NCBI Official Full Name

sex hormone-binding globulin isoform 1

NCBI Official Synonym Full Names

sex hormone-binding globulin

NCBI Official Symbol

SHBG

NCBI Official Synonym Symbols

ABP; SBP; TEBG

UniProt Protein Name

Sex hormone-binding globulin

UniProt Synonym Protein Names

Sex steroid-binding protein; SBP; Testis-specific androgen-binding protein; ABP; Testosterone-estradiol-binding globulin; TeBG; Testosterone-estrogen-binding globulin

Protein Family

Sex hormone-binding globulin

UniProt Gene Name

SHBG

UniProt Synonym Gene Names

SHBG; SBP; ABP; TeBG

UniProt Entry Name

SHBG_HUMAN

NCBI Protein Information

sex hormone-binding globulin; sex steroid-binding protein; testosterone-binding beta-globulin; testosterone-estrogen-binding globulin; testosterone-estradiol-binding globulin; testis-specific androgen-binding protein

NCBI Summary for SHBG

This gene encodes a steroid binding protein that was first described as a plasma protein secreted by the liver but is now thought to participate in the regulation of steroid responses. The encoded protein binds each steroid molecule as a dimer formed from identical or nearly identical monomers. The use of alternate promoters and alternatively spliced transcripts have been described. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2009]

UniProt Comments for SHBG

SHBG: Functions as an androgen transport protein, but may also be involved in receptor mediated processes. Each dimer binds one molecule of steroid. Specific for 5-alpha-dihydrotestosterone, testosterone, and 17-beta-estradiol. Regulates the plasma metabolic clearance rate of steroid hormones by controlling their plasma concentration. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 17p13.1

Cellular Component: extracellular region

Molecular Function: androgen binding

Biological Process: primary spermatocyte growth

Research Articles on SHBG

1. Letter: SHBG levels in combined oral contraceptive users may be seen as a marker for venous thrombosis risk.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with SHBG elisa kit

Reference Product	PubMed Publications
FSH elisa kit	>1050 publications with SHBG and FSH
PRL elisa kit	>192 publications with SHBG and PRL
IGFBP1 elisa kit	>98 publications with SHBG and IGFBP1
IGF1 elisa kit	>15 publications with SHBG and IGF1
INS elisa kit	>14 publications with SHBG and INS
SERPINA6 elisa kit	>2 publications with SHBG and SERPINA6
GNRH1 elisa kit	>1 publications with SHBG and GNRH1
SULT2A1 elisa kit	>1 publications with SHBG and SULT2A1

Pathways associated with SHBG elisa kit

Products by Pathway	Pathway Diagram
Nongenotropic Androgen Signaling Pathway antibodies	Nongenotropic Androgen Signaling Pathway Diagram

Diseases associated with SHBG elisa kit

Disease Name	Pubmed Publications
Neoplasms Antibodies	>1783 publications with SHBG and Neoplasms
Breast Neoplasms Antibodies	>519 publications with SHBG and Breast Neoplasms
Cardiovascular Diseases Antibodies	>456 publications with SHBG and Cardiovascular Diseases
Congenital Abnormalities Antibodies	>335 publications with SHBG and Congenital Abnormalities
Disorders of Sex Development Antibodies	>319 publications with SHBG and Disorders of Sex Development
Urogenital Abnormalities Antibodies	>318 publications with SHBG and Urogenital Abnormalities
Prostatic Neoplasms Antibodies	>236 publications with SHBG and Prostatic Neoplasms
Weight Loss Antibodies	>207 publications with SHBG and Weight Loss
Diabetes Mellitus, Type 2 Antibodies	>180 publications with SHBG and Diabetes Mellitus, Type 2
Hyperplasia Antibodies	>169 publications with SHBG and Hyperplasia

Organs/Tissues associated with SHBG elisa kit

Organ/Tissue Name	Pubmed Publications
Liver Antibodies	>512 publications with SHBG and Liver
Brain Antibodies	>324 publications with SHBG and Brain
Testis Antibodies	>312 publications with SHBG and Testis
Intestine Antibodies	>13 publications with SHBG and Intestine
Eye Antibodies	>11 publications with SHBG and Eye