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FRAT2 Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS420756

MBS420756 is an antibody targeting FRAT2. Also known as Goat anti-FRAT2/GSK-3 Antibody. Reactive in Tested: Human; Expected from sequence similarity: Human. Host: Goat. More details

$450 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
FRAT2/GSK-3, Polyclonal Antibody
Full Product Name
Goat anti-FRAT2/GSK-3 Antibody
Product Gene Name
Product Synonym Gene Name
GSK-3
Product Synonym Names
FRAT2; GSK-3; frequently rearranged in advanced T-cell lymphomas 2; GSK-3 binding protein FRAT2; RP11-452K12.2; MGC10562; FRAT2 antibody; GSK-3 antibody; frequently rearranged in advanced T-cell lymphomas 2 antibody; GSK-3 binding protein FRAT2 antibody; RP11-452K12.2 antibody; MGC10562 antibody; FRAT2 / GSK-3
Immunogen Sequence
GPDRIALQPS GSLL
Clonality
Polyclonal
Host
Goat
Species Reactivity
Tested: Human; Expected from sequence similarity: Human
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration
100ug specific antibody in 200ul (lot specific)
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.
Antibody/Peptide Pairs
Molecular Weight
24,051 Da
OMIM
605006
Immunogen
Peptide with sequence C-GPDRIALQPSGSLL, from the C Terminus of the protein sequence according to NP_036215.1.
Epitope
C Terminus
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Applications Tested/Suitable for anti-FRAT2 antibody
Peptide ELISA (EIA), Western Blot (WB)
Application Notes for anti-FRAT2 antibody
Peptide ELISA: Antibody detection limit dilution 1: 2000.
Western Blot: Approx 30-35kDa band seen in Human Heart lysate. Recommended for use at 1-3ug/ml.

Western Blot (WB) of anti-FRAT2 antibody

Staining (2ug/ml) of Human Heart lysate (RIPA buffer, 30ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.
Goat Anti-FRAT2 Polyclonal Antibody – Cat# MBS420756

Other Notes

Small volumes of anti-FRAT2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for FRAT2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
GSK-3-binding protein FRAT2
NCBI Official Synonym Full Names
frequently rearranged in advanced T-cell lymphomas 2
NCBI Official Symbol
FRAT2
UniProt Protein Name
GSK-3-binding protein FRAT2
UniProt Synonym Protein Names
Frequently rearranged in advanced T-cell lymphomas 2; FRAT-2
Protein Family
UniProt Gene Name
FRAT2
UniProt Synonym Gene Names
FRAT-2
UniProt Entry Name
FRAT2_HUMAN
NCBI Protein Information
GSK-3-binding protein FRAT2

NCBI Summary for FRAT2

The protein encoded by this intronless gene belongs to the GSK-3-binding protein family. Studies show that this protein plays a role as a positive regulator of the WNT signaling pathway. It may be upregulated in tumor progression. [provided by RefSeq, Jul 2008]

UniProt Comments for FRAT2

FRAT2: Positively regulates the Wnt signaling pathway by stabilizing beta-catenin through the association with GSK-3. Belongs to the GSK-3-binding protein family.

Protein type: Cell development/differentiation

Chromosomal Location of Human Ortholog: 10q24.1

Cellular Component: cytosol

Biological Process: cell proliferation; multicellular organismal development
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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