Goat Anti-BRSK2 Polyclonal Antibody – Cat# MBS420842

BRSK2 Antibody – Goat Polyclonal

Name: BRSK2 Antibody; Polyclonal; Goat; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS420842
Price: 450 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS420842

MBS420842 is an antibody targeting BRSK2. Also known as Goat anti-BRSK2/STK29 Antibody. Reactive in Expected from sequence similarity: Human, Mouse, Rat, Dog, Cow. Host: Goat. More details

$450 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

BRSK2/STK29, Polyclonal Antibody

Full Product Name

Goat anti-BRSK2/STK29 Antibody

Product Gene Name

anti-BRSK2 antibody

Product Synonym Gene Name

STK29

Product Synonym Names

BRSK2; SAD1; STK29; PEN11B; C11orf7; BR serine/threonine kinase 2; serine/threonine kinase 29; homolog of SAD-1 (C. elegans); chromosome 11 open reading frame 7; chromsosome 11 open reading frame 7; FLJ41362; protein kinase SAD1B; serine/threonine kinase; BRSK2 antibody; SAD1 antibody; STK29 antibody; PEN11B antibody; C11orf7 antibody; BR serine/threonine kinase 2 antibody; serine/threonine kinase 29 antibody; homolog of SAD-1 (C. elegans) antibody; chromosome 11 open reading frame 7 antibody; chromsosome 11 open reading frame 7 antibody; FLJ41362 antibody; protein kinase SAD1B antibody; serine/threonine kinase SAD-A antibody; BRSK2 / STK29

Immunogen Sequence

CPEVIRGEKY DGRKAD

Clonality

Polyclonal

Host

Goat

Species Reactivity

Expected from sequence similarity: Human, Mouse, Rat, Dog, Cow

Form/Format

Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Purity/Purification

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Concentration

100ug specific antibody in 200ul (lot specific)

Preparation and Storage

Aliquot and store at -20 degree C. Minimize freezing and thawing.

Antibody/Peptide Pairs

BRSK2 / STK29 peptide (MBS425274) is used for blocking the activity of BRSK2/STK29 antibody (MBS420842)

Molecular Weight

68,740 Da

OMIM

609236

Immunogen

Peptide with sequence CPEVIRGEKYDGRKAD, from the internal region of the protein sequence according to NP_003948.2.

Epitope

Internal region

ISO Certification

Manufactured in an ISO 9001:2008 Certified Laboratory.

Applications Tested/Suitable for anti-BRSK2 antibody

Peptide ELISA (EIA)

Application Notes for anti-BRSK2 antibody

Peptide ELISA: Antibody detection limit dilution 1: 8000.
Western Blot: Preliminary experiments gave bands at approx 50-55kDa and 15kDa in human brain, mouse brain and rat brain lysates after 0.5ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the bands we observe given the calculated size of 74.7kDa according to NP_003948.2. Both detected bands were successfully blocked by incubation with the immunizing peptide (and BLAST results with the immunizing peptide sequence did not identify any other proteins to explain the bands).

Other Notes

Small volumes of anti-BRSK2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for BRSK2. It may not necessarily be applicable to this product.

NCBI GI #

116089335

NCBI GeneID

9024

NCBI Accession #

NP_003948.2

UniProt Secondary Accession #

O60843; O95099; Q5J5B4; Q6ZMQ4; Q8TB60; B3KVE9; E9PLM7

UniProt Related Accession #

Q8IWQ3

GenBank Nucleotide #

NM_003957.3

NCBI Official Full Name

serine/threonine-protein kinase BRSK2 isoform 2

NCBI Official Synonym Full Names

BR serine/threonine kinase 2

NCBI Official Symbol

BRSK2

NCBI Official Synonym Symbols

SAD1; SADA; STK29; PEN11B; C11orf7

UniProt Protein Name

Serine/threonine-protein kinase BRSK2

UniProt Synonym Protein Names

Brain-selective kinase 2 (EC:2.7.11.26); Brain-specific serine/threonine-protein kinase 2; BR serine/threonine-protein kinase 2; Serine/threonine-protein kinase 29; Serine/threonine-protein kinase SAD-A

Protein Family

Serine/threonine-protein kinase

UniProt Gene Name

BRSK2

UniProt Synonym Gene Names

C11orf7; PEN11B; SADA; STK29; BR serine/threonine-protein kinase 2

UniProt Entry Name

BRSK2_HUMAN

NCBI Protein Information

serine/threonine-protein kinase BRSK2

UniProt Comments for BRSK2

BRSK2: a serine/threonine protein kinase of the CAMK group. Closely related to AMPK. Activated by the kinase LKB1. BRSK1 and BRSK2 are required for nueronal polarization. Expressed in the brain and at low levels in the testis. Four alternatively spliced isoforms have been described.

Protein type: EC 2.7.11.26; Protein kinase, Ser/Thr (non-receptor); Kinase, protein; EC 2.7.11.1; Protein kinase, CAMK; CAMK group; CAMKL family; BRSK subfamily

Chromosomal Location of Human Ortholog: 11p15.5

Cellular Component: centrosome; cytoplasm; endoplasmic reticulum; nucleus; perinuclear region of cytoplasm

Molecular Function: ATP binding; ATPase binding; magnesium ion binding; protein kinase binding; protein serine/threonine kinase activity; tau-protein kinase activity

Biological Process: actin cytoskeleton reorganization; axonogenesis; cell division; establishment of cell polarity; exocytosis; G2/M transition of mitotic cell cycle; mitosis; neuron differentiation; peptidyl-serine phosphorylation; protein amino acid phosphorylation; regulation of ATPase activity

Research Articles on BRSK2

1. SAD-A and AMPK kinases are regulators of mTORC1 signaling in the pancreatic beta-cells.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-BRSK2 antibody

Reference Product	PubMed Publications
STK11 antibody	>7 publications with BRSK2 and STK11
WEE1 antibody	>1 publications with BRSK2 and WEE1

Pathways associated with anti-BRSK2 antibody

Products by Pathway	Pathway Diagram
LKB1 Signaling Events Pathway antibodies	LKB1 Signaling Events Pathway Diagram

Diseases associated with anti-BRSK2 antibody

Disease Name	Pubmed Publications
Neoplasm Metastasis Antibodies	>2 publications with BRSK2 and Neoplasm Metastasis

Organs/Tissues associated with anti-BRSK2 antibody

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>19 publications with BRSK2 and Brain
Liver Antibodies	>2 publications with BRSK2 and Liver
Lung Antibodies	>1 publications with BRSK2 and Lung
Testis Antibodies	>1 publications with BRSK2 and Testis