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PSCD4/Cytohesin 4 (CYTH4) Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS420855

MBS420855 is an antibody targeting CYTH4. Also known as Goat anti-PSCD4/CYTOHESIN 4 Antibody. Reactive in Expected from sequence similarity: Human. Host: Goat. More details

$305 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PSCD4/CYTOHESIN 4 (CYTH4), Polyclonal Antibody
Full Product Name
Goat anti-PSCD4/CYTOHESIN 4 Antibody
Product Gene Name
Product Synonym Gene Name
CYTOHESIN 4
Product Synonym Names
Goat Anti-PSCD4 Antibody; CYTH4; PSCD4; CYT4; DJ63G5.1; CYTOHESIN-4; pleckstrin homology, Sec7 and coiled/coil domains 4; cytohesin-4; cytohesin 4; cytohesin-4; pleckstrin homology, Sec7 and coiled-coil domains 4; CYTH4 antibody; PSCD4 antibody; CYT4 antibody; DJ63G5.1 antibody; CYTOHESIN-4 antibody; pleckstrin homology; Sec7 and coiled/coil domains 4 antibody; cytohesin-4 antibody; cytohesin 4 antibody; cytohesin-4 antibody; pleckstrin homology; Sec7 and coiled-coil domains 4 antibody; PSCD4 / CYTOHESIN 4
Immunogen Sequence
DLCHPEPAEL SSG
Clonality
Polyclonal
Host
Goat
Species Reactivity
Expected from sequence similarity: Human
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration
100ug specific antibody in 200ul (lot specific)
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.
Antibody/Peptide Pairs
Molecular Weight
45,672 Da
OMIM
606514
Immunogen
Peptide with sequence DLCHPEPAELSSG, from the N Terminus of the protein sequence according to NP_037517.1.
Epitope
N Terminus
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Applications Tested/Suitable for anti-CYTH4 antibody
Peptide ELISA (EIA)
Application Notes for anti-CYTH4 antibody
Peptide ELISA: Antibody detection limit dilution 1: 32000.
Western Blot: Preliminary experiments gave no signal but low background in Human Kidney and Brain lysates at up to 1ug/ml.

Other Notes

Small volumes of anti-CYTH4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CYTH4. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
cytohesin-4 isoform 1
NCBI Official Synonym Full Names
cytohesin 4
NCBI Official Symbol
CYTH4
NCBI Official Synonym Symbols
CYT4; PSCD4; DJ63G5.1
UniProt Protein Name
Cytohesin-4
UniProt Synonym Protein Names
PH, SEC7 and coiled-coil domain-containing protein 4
Protein Family
UniProt Gene Name
CYTH4
UniProt Synonym Gene Names
CYT4; PSCD4
UniProt Entry Name
CYH4_HUMAN
NCBI Protein Information
cytohesin-4

NCBI Summary for CYTH4

This gene encodes a member of the PSCD family of proteins, which have an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family function as GEPs for ADP-ribosylation factors (ARFs), which are guanine nucleotide-binding proteins involved in vesicular trafficking pathways. This protein exhibits GEP activity in vitro with ARF1 and ARF5, but is inactive with ARF6. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2015]
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UniProt Comments for CYTH4

cytohesin 4: Promotes guanine-nucleotide exchange on ARF1 and ARF5. Promotes the activation of ARF through replacement of GDP with GTP.

Protein type: GEFs; GEFs, ARF

Chromosomal Location of Human Ortholog: 22q12.3-q13.1

Cellular Component: cytosol; Golgi membrane; plasma membrane

Molecular Function: ARF guanyl-nucleotide exchange factor activity; lipid binding

Biological Process: positive regulation of GTPase activity; regulation of ARF protein signal transduction
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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