• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

HTATSF1 Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS420880

MBS420880 is an antibody targeting HTATSF1. Also known as Goat anti-HTATSF1 Antibody. Reactive in Tested: Human; Expected from sequence similarity: Human, Rat, Dog. Host: Goat. More details

$450 / 0.1 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
HTATSF1, Polyclonal Antibody
Full Product Name
Goat anti-HTATSF1 Antibody
Product Gene Name
anti-HTATSF1 antibody
Product Synonym Names
HTATSF1; HIV-1 Tat specific factor 1; RP1-196E23.2; TAT-SF1; dJ196E23.2; HIV TAT specific factor 1; cofactor required for Tat activation of HIV-1 transcription; HTATSF1 antibody; HIV-1 Tat specific factor 1 antibody; RP1-196E23.2 antibody; TAT-SF1 antibody; dJ196E23.2 antibody; HIV TAT specific factor 1 antibody; cofactor required for Tat activation of HIV-1 transcription antibody
Immunogen Sequence
QELYGDGKDG DTQTD
Clonality
Polyclonal
Host
Goat
Species Reactivity
Tested: Human; Expected from sequence similarity: Human, Rat, Dog
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration
100ug specific antibody in 200ul (lot specific)
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.
Antibody/Peptide Pairs
HTATSF1 peptide (MBS426301) is used for blocking the activity of HTATSF1 antibody (MBS420880)
Molecular Weight
85,853 Da
OMIM
300346
Immunogen
Peptide with sequence C-QELYGDGKDGDTQTD, from the internal region (near the N Terminus) of the protein sequence according to NP_055315.2.
Epitope
Internal region (near the N Terminus)
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Applications Tested/Suitable for anti-HTATSF1 antibody
Peptide ELISA (EIA), Western Blot (WB)
Application Notes for anti-HTATSF1 antibody
Peptide ELISA: Antibody detection limit dilution 1: 16000.

Western Blot (WB) of anti-HTATSF1 antibody

(1ug/ml) staining of Daudi cell lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Goat Anti-HTATSF1 Polyclonal Antibody – Cat# MBS420880

Other Notes

Small volumes of anti-HTATSF1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for HTATSF1. It may not necessarily be applicable to this product.

NCBI GI #
21361437
NCBI GeneID
27336
NCBI Accession #
NP_055315.2
UniProt Secondary Accession #
Q59G06; Q99730; D3DWG9
UniProt Related Accession #
O43719
GenBank Nucleotide #
NM_014500.4
NCBI Official Full Name
HIV Tat-specific factor 1
NCBI Official Synonym Full Names
HIV-1 Tat specific factor 1
NCBI Official Symbol
HTATSF1
NCBI Official Synonym Symbols
TATSF1; TAT-SF1; dJ196E23.2
UniProt Protein Name
HIV Tat-specific factor 1
Protein Family
HIV Tat-specific factor
UniProt Gene Name
HTATSF1
UniProt Synonym Gene Names
Tat-SF1
UniProt Entry Name
HTSF1_HUMAN
NCBI Protein Information
HIV Tat-specific factor 1

NCBI Summary for HTATSF1

The protein encoded by this gene functions as a cofactor for the stimulation of transcriptional elongation by HIV-1 Tat, which binds to the HIV-1 promoter through Tat-TAR interaction. This protein may also serve as a dual-function factor to couple transcription and splicing and to facilitate their reciprocal activation. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Sep 2009]
Show more

UniProt Comments for HTATSF1

TAT-SF1: Functions as a general transcription factor playing a role in the process of transcriptional elongation. May mediate the reciprocal stimulatory effect of splicing on transcriptional elongation. In case of infection by HIV-1, it is up-regulated by the HIV-1 proteins NEF and gp120, acts as a cofactor required for the Tat-enhanced transcription of the virus. Belongs to the HTATSF1 family.

Protein type: Transcription, coactivator/corepressor; Spliceosome

Chromosomal Location of Human Ortholog: Xq26.3

Cellular Component: nucleoplasm; nucleus; snRNP U2

Molecular Function: nucleotide binding; RNA binding

Biological Process: nuclear mRNA splicing, via spliceosome; regulation of RNA elongation; regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent; viral genome replication
Show more

Research Articles on HTATSF1

1. This study validates Tat-SF1 as an HDF in CD4+ T cell-derived SupT1 cells.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-HTATSF1 antibody

 Disease Name  Pubmed Publications
 Anemia Antibodies  >1 publications with HTATSF1 and Anemia

Organs/Tissues associated with anti-HTATSF1 antibody

 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >1 publications with HTATSF1 and Muscle
 Liver Antibodies  >1 publications with HTATSF1 and Liver
 Testis Antibodies  >1 publications with HTATSF1 and Testis
 Blood Antibodies  >1 publications with HTATSF1 and Blood
 Kidney Antibodies  >1 publications with HTATSF1 and Kidney
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000