• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

VTI1B Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS420977

MBS420977 is an antibody targeting VTI1B. Also known as Goat anti-VTI1B Antibody. Reactive in Tested: Human; Expected from sequence similarity: Human, Mouse, Rat, Dog. Host: Goat. More details

$450 / 0.1 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
VTI1B, Polyclonal Antibody
Full Product Name
Goat anti-VTI1B Antibody
Product Gene Name
anti-VTI1B antibody
Product Synonym Names
VTI1B; vesicle transport through interaction with t-SNAREs homolog 1B (yeast); HGNC: 17793; VTI1; VTI1L; VTI2; v-SNARE; vesicle transport through interaction with t-SNAREs 1B; vesicle-associated soluble NSF attachment protein receptor; VTI1B antibody; vesicle transport through interaction with t-SNAREs homolog 1B (yeast) antibody; HGNC: 17793 antibody; VTI1 antibody; VTI1L antibody; VTI2 antibody; v-SNARE antibody; vesicle transport through interaction with t-SNAREs 1B antibody; vesicle-associated soluble NSF attachment protein receptor antibody
Immunogen Sequence
RDFDEKQQEA NET
Clonality
Polyclonal
Host
Goat
Species Reactivity
Tested: Human; Expected from sequence similarity: Human, Mouse, Rat, Dog
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration
100ug specific antibody in 200ul (lot specific)
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.
Antibody/Peptide Pairs
VTI1B peptide (MBS425480) is used for blocking the activity of VTI1B antibody (MBS420977)
Molecular Weight
19,810 Da
OMIM
603207
Immunogen
Peptide with sequence C-RDFDEKQQEANET, from the internal region of the protein sequence according to NP_006361.1.
Epitope
Internal region
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Applications Tested/Suitable for anti-VTI1B antibody
Peptide ELISA (EIA), Western Blot (WB)
Application Notes for anti-VTI1B antibody
Peptide ELISA: Antibody detection limit dilution 1: 32000.
Western Blot: Approx 26-28kDa band observed in Human Duodenum, Kidney and Testes lysates (calculated MW of 26.7kDa according to NP_006361.1). Recommended concentration: 1-3ug/ml.

Western Blot (WB) of anti-VTI1B antibody

(1ug/ml) staining of Human Duodenum lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Goat Anti-VTI1B Polyclonal Antibody – Cat# MBS420977

Other Notes

Small volumes of anti-VTI1B antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for VTI1B. It may not necessarily be applicable to this product.

NCBI GI #
5454166
NCBI GeneID
10490
NCBI Accession #
NP_006361.1
UniProt Secondary Accession #
O43547; Q96J28
UniProt Related Accession #
Q9UEU0
GenBank Nucleotide #
NM_006370.2
NCBI Official Full Name
vesicle transport through interaction with t-SNAREs homolog 1B
NCBI Official Synonym Full Names
vesicle transport through interaction with t-SNAREs 1B
NCBI Official Symbol
VTI1B
NCBI Official Synonym Symbols
VTI1; VTI2; VTI1L; v-SNARE; vti1-rp1; VTI1-LIKE
UniProt Protein Name
Vesicle transport through interaction with t-SNAREs homolog 1B
UniProt Synonym Protein Names
Vesicle transport v-SNARE protein Vti1-like 1; Vti1-rp1
Protein Family
Vesicle transport through interaction with t-SNAREs
UniProt Gene Name
VTI1B
UniProt Synonym Gene Names
VTI1; VTI1L; VTI1L1; VTI2
UniProt Entry Name
VTI1B_HUMAN
NCBI Protein Information
vesicle transport through interaction with t-SNAREs homolog 1B

UniProt Comments for VTI1B

VTI1B: V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. May be concerned with increased secretion of cytokines associated with cellular senescence. Belongs to the VTI1 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Vesicle; Membrane protein, integral

Chromosomal Location of Human Ortholog: 14q24.1

Cellular Component: cell soma; cytoplasm; cytosol; endoplasmic reticulum membrane; Golgi apparatus; integral to membrane; intracellular membrane-bound organelle; late endosome membrane; lysosomal membrane; perinuclear region of cytoplasm; recycling endosome; SNARE complex; synaptic vesicle; vesicle

Molecular Function: chloride channel inhibitor activity; protein binding; SNAP receptor activity; SNARE binding

Biological Process: cell proliferation; ER to Golgi vesicle-mediated transport; Golgi to vacuole transport; intra-Golgi vesicle-mediated transport; protein targeting to vacuole; retrograde transport, endosome to Golgi; vesicle docking during exocytosis; vesicle fusion with Golgi apparatus; vesicle-mediated transport
Show more

Research Articles on VTI1B

1. Vti1b-dependent tethering of Lytic granule and CD3-endo determines accumulation, docking, and efficient lytic granule secretion at the immunological synapse.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-VTI1B antibody

 Reference Product  PubMed Publications
 VAMP7 antibody  >6 publications with VTI1B and VAMP7
 STX6 antibody  >4 publications with VTI1B and STX6
 STX7 antibody  >4 publications with VTI1B and STX7
 STX8 antibody  >4 publications with VTI1B and STX8
 CLINT1 antibody  >3 publications with VTI1B and CLINT1
 VAMP4 antibody  >1 publications with VTI1B and VAMP4
 STX4 antibody  >1 publications with VTI1B and STX4

Pathways associated with anti-VTI1B antibody

 Products by Pathway  Pathway Diagram
 SNARE Interactions In Vesicular Transport Pathway antibodies  SNARE Interactions In Vesicular Transport Pathway Diagram
 SNARE Interactions In Vesicular Transport Pathway antibodies  SNARE Interactions In Vesicular Transport Pathway Diagram

Diseases associated with anti-VTI1B antibody

 Disease Name  Pubmed Publications
 Disease Models, Animal Antibodies  >2 publications with VTI1B and Disease Models, Animal
 Necrosis Antibodies  >2 publications with VTI1B and Necrosis
 Breast Neoplasms Antibodies  >1 publications with VTI1B and Breast Neoplasms
 Carcinoma Antibodies  >1 publications with VTI1B and Carcinoma
 Edema Antibodies  >1 publications with VTI1B and Edema
 Inflammation Antibodies  >1 publications with VTI1B and Inflammation

Organs/Tissues associated with anti-VTI1B antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >5 publications with VTI1B and Blood
 Nerve Antibodies  >3 publications with VTI1B and Nerve
 Bone Antibodies  >2 publications with VTI1B and Bone
 Liver Antibodies  >2 publications with VTI1B and Liver
 Bone Marrow Antibodies  >2 publications with VTI1B and Bone Marrow
 Lung Antibodies  >2 publications with VTI1B and Lung
 Brain Antibodies  >2 publications with VTI1B and Brain
 Ganglia Antibodies  >1 publications with VTI1B and Ganglia
 Salivary Gland Antibodies  >1 publications with VTI1B and Salivary Gland
 Mouth Antibodies  >1 publications with VTI1B and Mouth
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000