Goat Anti-DNM3 Polyclonal Antibody – Cat# MBS421030

Dynamin 3 (DNM3) Antibody – Goat Polyclonal

Name: DNM3 Antibody; Polyclonal; Goat; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS421030
Price: 450 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS421030

MBS421030 is an antibody targeting DNM3. Also known as Goat anti-Dynamin 3 Antibody. Reactive in Expected from sequence similarity: Human. Host: Goat. More details

$450 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Dynamin 3 (DNM3), Polyclonal Antibody

Full Product Name

Goat anti-Dynamin 3 Antibody

Product Gene Name

anti-DNM3 antibody

Product Synonym Names

dynamin 3; Dyna III; KIAA0820; MGC70433; dynamin family member; dynamin 3 antibody; Dyna III antibody; KIAA0820 antibody; MGC70433 antibody; dynamin family member antibody; Dynamin 3; Dynamin 3

Immunogen Sequence

DKSVGNNKAE ND

Clonality

Polyclonal

Host

Goat

Species Reactivity

Expected from sequence similarity: Human

Form/Format

Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Purity/Purification

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Concentration

100ug specific antibody in 200ul (lot specific)

Preparation and Storage

Aliquot and store at -20 degree C. Minimize freezing and thawing.

Antibody/Peptide Pairs

Dynamin 3 peptide (MBS425819) is used for blocking the activity of Dynamin 3 antibody (MBS421030)

Molecular Weight

62,824 Da

OMIM

611445

Immunogen

Peptide with sequence C-DKSVGNNKAEND, from the internal region of the protein sequence according to NP_056384.2.

Epitope

Internal region

ISO Certification

Manufactured in an ISO 9001:2008 Certified Laboratory.

Applications Tested/Suitable for anti-DNM3 antibody

Peptide ELISA (EIA)

Application Notes for anti-DNM3 antibody

Peptide ELISA: Antibody detection limit dilution 1: 1000.
Western Blot: Preliminary experiments gave an approx 26kDa band in Human Brain (Amygdala and Cerebellum), Kidney and Liver lysates after 0.3ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 97.1kDa according to NP_056384.2. The 26kDa band was successfully blocked by incubation with the immunizing peptide.

Other Notes

Small volumes of anti-DNM3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for DNM3. It may not necessarily be applicable to this product.

NCBI GI #

42544243

NCBI GeneID

26052

NCBI Accession #

NP_056384.2

UniProt Secondary Accession #

O14982; O95555; Q1MTM8; Q5W129; Q6P2G1; Q9H0P3; Q9H548; Q9NQ68; Q9NQN6; A9Z1Y1

UniProt Related Accession #

Q9UQ16

GenBank Nucleotide #

NM_015569.4

NCBI Official Full Name

dynamin-3 isoform a

NCBI Official Synonym Full Names

dynamin 3

NCBI Official Symbol

DNM3

NCBI Official Synonym Symbols

Dyna III

UniProt Protein Name

Dynamin-3

UniProt Synonym Protein Names

Dynamin, testicular; T-dynamin

Protein Family

Dynamin

UniProt Gene Name

DNM3

UniProt Synonym Gene Names

KIAA0820

UniProt Entry Name

DYN3_HUMAN

NCBI Protein Information

dynamin-3

NCBI Summary for DNM3

This gene encodes a member of a family of guanosine triphosphate (GTP)-binding proteins that associate with microtubules and are involved in vesicular transport. The encoded protein functions in the development of megakaryocytes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]

UniProt Comments for DNM3

DYN3: a microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes. Concentrates within dendritic spine tips of the postsynaptic compartment and interacts with mGluR5 and Homer. May play a role in dendritic spine morphogenesis and remodeling.

Protein type: Motor; Motility/polarity/chemotaxis; Vesicle; EC 3.6.5.5; Microtubule-binding; Mitochondrial; Hydrolase

Chromosomal Location of Human Ortholog: 1q24.3

Cellular Component: axon; dendritic spine; Golgi apparatus; microtubule; mitochondrion; perinuclear region of cytoplasm; photoreceptor inner segment; postsynaptic density

Molecular Function: GTP binding; GTPase activity; nitric-oxide synthase binding; protein binding; type 1 metabotropic glutamate receptor binding; type 5 metabotropic glutamate receptor binding

Biological Process: endocytosis; filopodium formation; metabolic process; positive regulation of filopodium formation; synaptogenesis

Research Articles on DNM3

1. Data show that the classical dynamin DNM1 and DNM3 genes reach their maximum expression levels (100% of maximal expression) in all normal central nervous system tissues studied.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-DNM3 antibody

Products by Pathway	Pathway Diagram
Adaptive Immune System Pathway antibodies	Adaptive Immune System Pathway Diagram
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Bacterial Invasion Of Epithelial Cells Pathway antibodies	Bacterial Invasion Of Epithelial Cells Pathway Diagram
Bacterial Invasion Of Epithelial Cells Pathway antibodies	Bacterial Invasion Of Epithelial Cells Pathway Diagram
Developmental Biology Pathway antibodies	Developmental Biology Pathway Diagram
Endocrine And Other Factor-regulated Calcium Reabsorption Pathway antibodies	Endocrine And Other Factor-regulated Calcium Reabsorption Pathway Diagram
Endocrine And Other Factor-regulated Calcium Reabsorption Pathway antibodies	Endocrine And Other Factor-regulated Calcium Reabsorption Pathway Diagram
Endocytosis Pathway antibodies	Endocytosis Pathway Diagram
Endocytosis Pathway antibodies	Endocytosis Pathway Diagram
Immune System Pathway antibodies	Immune System Pathway Diagram

Diseases associated with anti-DNM3 antibody

Disease Name	Pubmed Publications
Nervous System Diseases Antibodies	>4 publications with DNM3 and Nervous System Diseases
Brain Diseases Antibodies	>2 publications with DNM3 and Brain Diseases
Abnormalities, Multiple Antibodies	>2 publications with DNM3 and Abnormalities, Multiple
Lung Neoplasms Antibodies	>1 publications with DNM3 and Lung Neoplasms
Proteinuria Antibodies	>1 publications with DNM3 and Proteinuria
Lung Diseases Antibodies	>1 publications with DNM3 and Lung Diseases
Kidney Diseases Antibodies	>1 publications with DNM3 and Kidney Diseases
Inflammation Antibodies	>1 publications with DNM3 and Inflammation

Organs/Tissues associated with anti-DNM3 antibody

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>9 publications with DNM3 and Blood
Brain Antibodies	>6 publications with DNM3 and Brain
Connective Tissue Antibodies	>3 publications with DNM3 and Connective Tissue
Lung Antibodies	>2 publications with DNM3 and Lung
Muscle Antibodies	>2 publications with DNM3 and Muscle
Kidney Antibodies	>2 publications with DNM3 and Kidney
Embryonic Tissue Antibodies	>2 publications with DNM3 and Embryonic Tissue
Uterus Antibodies	>1 publications with DNM3 and Uterus
Ear Antibodies	>1 publications with DNM3 and Ear
Placenta Antibodies	>1 publications with DNM3 and Placenta