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GULP1 Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS421093

MBS421093 is an antibody targeting GULP1. Also known as Goat anti-GULP1/CED6 Antibody. Reactive in Tested: Human; Expected from sequence similarity: Human, Mouse, Rat, Dog. Host: Goat. More details

$450 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
GULP1/CED6, Polyclonal Antibody
Full Product Name
Goat anti-GULP1/CED6 Antibody
Product Gene Name
Product Synonym Gene Name
CED6
Product Synonym Names
CED-6; GULP1; CED-6 protein; GULP, engulfment adaptor PTB domain containing 1; CED6; FLJ31156; OTTHUMP00000205908; OTTHUMP00000205909; OTTHUMP00000205911; PTB domain adaptor protein CED-6; engulfment adapter protein; CED-6 antibody; GULP1 antibody; CED-6 protein antibody; GULP; engulfment adaptor PTB domain containing 1 antibody; CED6 antibody; FLJ31156 antibody; OTTHUMP00000205908 antibody; OTTHUMP00000205909 antibody; OTTHUMP00000205911 antibody; PTB domain adaptor protein CED-6 antibody; engulfment adapter protein antibody; GULP1 / CED6
Immunogen Sequence
EGTVFCLDPL DSRC
Clonality
Polyclonal
Host
Goat
Species Reactivity
Tested: Human; Expected from sequence similarity: Human, Mouse, Rat, Dog
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration
100ug specific antibody in 200ul (lot specific)
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.
Antibody/Peptide Pairs
Molecular Weight
33,333 Da
OMIM
608165
Immunogen
Peptide with sequence EGTVFCLDPLDSRC, from the C Terminus of the protein sequence according to NP_057399.1.
Epitope
C Terminus
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Applications Tested/Suitable for anti-GULP1 antibody
Peptide ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-GULP1 antibody
Peptide ELISA: Antibody detection limit dilution 1: 64000.
Immunohistochemistry: In paraffin embedded Human Kidney shows staining of cytoplasm, stronger in a selection of epithelial cells of distal convoluted tubules. Recommended concentration, 5-10 ug/ml.

Western Blot (WB) of anti-GULP1 antibody

Staining (0.2ug/ml) of Human Placenta lysate (RIPA buffer, 30ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.
Goat Anti-GULP1 Polyclonal Antibody – Cat# MBS421093

Immunohistochemistry (IHC) of anti-GULP1 antibody

(5ug/ml) staining of paraffin embedded Human Kidney. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
Goat Anti-GULP1 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS421093

Other Notes

Small volumes of anti-GULP1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for GULP1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
PTB domain-containing engulfment adapter protein 1 isoform a
NCBI Official Synonym Full Names
GULP, engulfment adaptor PTB domain containing 1
NCBI Official Symbol
GULP1
NCBI Official Synonym Symbols
CED6; GULP; CED-6
UniProt Protein Name
PTB domain-containing engulfment adapter protein 1
UniProt Synonym Protein Names
Cell death protein 6 homolog; PTB domain adapter protein CED-6; Protein GULP
UniProt Gene Name
GULP1
UniProt Synonym Gene Names
CED6; GULP
UniProt Entry Name
GULP1_HUMAN
NCBI Protein Information
PTB domain-containing engulfment adapter protein 1

NCBI Summary for GULP1

The protein encoded by this gene is an adapter protein necessary for the engulfment of apoptotic cells by phagocytes. Several transcript variants, some protein coding and some thought not to be protein coding, have been found for this gene. [provided by RefSeq, Nov 2011]

UniProt Comments for GULP1

GULP1: May function as an adapter protein. Required for efficient phagocytosis of apoptotic cells. Modulates cellular glycosphingolipid and cholesterol transport. May play a role in the internalization and endosomal trafficking of various LRP1 ligands, such as PSAP. Increases cellular levels of GTP-bound ARF6. Belongs to the ced-6 family. 2 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 2q32.3-q33

Cellular Component: cytoplasm

Molecular Function: signal transducer activity

Biological Process: apoptosis; lipid transport; phagocytosis, engulfment; signal transduction
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Research Articles on GULP1

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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