Goat Anti-SOX15 Polyclonal Antibody – Cat# MBS421314

(0.1ug/ml) staining of Human Muscle lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

SOX15 Antibody – Goat Polyclonal

Name: SOX15 Antibody; Polyclonal; Goat; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS421314
Price: 450 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS421314

MBS421314 is an antibody targeting SOX15. Also known as Goat anti-SOX15 Antibody. Reactive in Tested: Human; Expected from sequence similarity: Human. Host: Goat. More details

$450 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

SOX15, Polyclonal Antibody

Full Product Name

Goat anti-SOX15 Antibody

Product Gene Name

anti-SOX15 antibody

Product Synonym Names

SRY (sex determining region Y)-box 15; SOX20; SOX26; SOX27; SRY (sex determining region Y)-box 20; SRY-box 15; SRY (sex determining region Y)-box 15 antibody; SOX20 antibody; SOX26 antibody; SOX27 antibody; SRY (sex determining region Y)-box 20 antibody; SRY-box 15 antibody

Immunogen Sequence

CSLPQSDPRL QGE

Clonality

Polyclonal

Host

Goat

Species Reactivity

Tested: Human; Expected from sequence similarity: Human

Form/Format

Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Purity/Purification

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Concentration

100ug specific antibody in 200ul (lot specific)

Preparation and Storage

Aliquot and store at -20 degree C. Minimize freezing and thawing.

Antibody/Peptide Pairs

SOX15 peptide (MBS425972) is used for blocking the activity of SOX15 antibody (MBS421314)

Molecular Weight

19,393 Da

OMIM

601297

Immunogen

Peptide with sequence CSLPQSDPRLQGE, from the internal region of the protein sequence according to NP_008873.1.

Epitope

Internal region

ISO Certification

Manufactured in an ISO 9001:2008 Certified Laboratory.

Applications Tested/Suitable for anti-SOX15 antibody

Peptide ELISA (EIA), Western Blot (WB)

Application Notes for anti-SOX15 antibody

Peptide ELISA: Antibody detection limit dilution 1: 16000.
Western Blot: Approx 24kDa band observed in Human Skeletal Muscle lysates (calculated MW of 25.3kDa according to NP_008873.1). Recommended concentration: 0.1-0.3ug/ml.

Other Notes

Small volumes of anti-SOX15 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for SOX15. It may not necessarily be applicable to this product.

NCBI GI #

5902106

NCBI GeneID

6665

NCBI Accession #

NP_008873.1

UniProt Secondary Accession #

P35717; Q9Y6W7; B4DWU7; D3DTQ0

UniProt Related Accession #

O60248

GenBank Nucleotide #

NM_006942.1

NCBI Official Full Name

protein SOX-15

NCBI Official Synonym Full Names

SRY-box 15

NCBI Official Symbol

SOX15

NCBI Official Synonym Symbols

SOX20; SOX26; SOX27

UniProt Protein Name

Protein SOX-15

UniProt Synonym Protein Names

Protein SOX-12; Protein SOX-20

Protein Family

Protein

UniProt Gene Name

SOX15

UniProt Synonym Gene Names

SOX12; SOX20; SOX26; SOX27

UniProt Entry Name

SOX15_HUMAN

NCBI Protein Information

protein SOX-15

NCBI Summary for SOX15

This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. [provided by RefSeq, Jul 2008]

UniProt Comments for SOX15

SOX15: Binds to the 5'-AACAAT-3' sequence.

Protein type: Cell development/differentiation; DNA-binding; Transcription factor

Chromosomal Location of Human Ortholog: 17p13.1

Cellular Component: cytoplasm; nucleus

Molecular Function: chromatin binding; DNA binding; protein binding; protein heterodimerization activity; transcription factor activity

Biological Process: cell differentiation; establishment and/or maintenance of chromatin architecture; male gonad development; myoblast development; negative regulation of striated muscle development; negative regulation of transcription from RNA polymerase II promoter; positive regulation of satellite cell activation involved in skeletal muscle regeneration; positive regulation of transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; skeletal muscle regeneration

Research Articles on SOX15

1. Results indicate that the expression of SOX15 in pancreatic cancer cell lines with undetectable expression resulted in reduced viability of cancer cells both in vitro and in vivo demonstrating its tumor suppressive capability.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-SOX15 antibody

Disease Name	Pubmed Publications
Lung Neoplasms Antibodies	>1 publications with SOX15 and Lung Neoplasms
Necrosis Antibodies	>1 publications with SOX15 and Necrosis

Organs/Tissues associated with anti-SOX15 antibody

Organ/Tissue Name	Pubmed Publications
Embryonic Tissue Antibodies	>9 publications with SOX15 and Embryonic Tissue
Testis Antibodies	>6 publications with SOX15 and Testis
Placenta Antibodies	>4 publications with SOX15 and Placenta
Pancreas Antibodies	>2 publications with SOX15 and Pancreas
Ovary Antibodies	>2 publications with SOX15 and Ovary
Lung Antibodies	>2 publications with SOX15 and Lung
Liver Antibodies	>1 publications with SOX15 and Liver
Esophagus Antibodies	>1 publications with SOX15 and Esophagus
Brain Antibodies	>1 publications with SOX15 and Brain