Goat Anti-SENP7 Polyclonal Antibody – Cat# MBS421443

SENP7 Antibody – Goat Polyclonal

Name: SENP7 Antibody; Polyclonal; Goat; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS421443
Price: 295 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS421443

MBS421443 is an antibody targeting SENP7. Also known as Goat anti-SENP7 (internal region) Antibody. Reactive in Expected from sequence similarity: Human, Mouse, Rat, Cow. Host: Goat. More details

DISCONTINUED
Click here to view our similar product(s) OR click here to contact our technical support team for suitable replacement.

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

SENP7, Polyclonal Antibody

Full Product Name

Goat anti-SENP7 (internal region) Antibody

Product Gene Name

anti-SENP7 antibody

Product Synonym Names

SENP7; SUMO1/sentrin specific peptidase 7; KIAA1707; MGC157730; SUMO1/sentrin specific protease 7; sentrin/SUMO-specific protease; sentrin/SUMO-specific protease 7; SENP7 antibody; SUMO1/sentrin specific peptidase 7 antibody; KIAA1707 antibody; MGC157730 antibody; SUMO1/sentrin specific protease 7 antibody; sentrin/SUMO-specific protease antibody; sentrin/SUMO-specific protease 7 antibody; SENP7 (internal region)

Immunogen Sequence

TRKENNLTED NPN

Clonality

Polyclonal

Host

Goat

Species Reactivity

Expected from sequence similarity: Human, Mouse, Rat, Cow

Form/Format

Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Purity/Purification

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Concentration

100ug specific antibody in 200ul (lot specific)

Preparation and Storage

Aliquot and store at -20 degree C. Minimize freezing and thawing.

Molecular Weight

112,159 Da

OMIM

612846

Immunogen

Peptide with sequence C-TRKENNLTEDNPN, from the internal region of the protein sequence according to NP_001070671.1; NP_065705.3.

Epitope

Internal region

Note

This antibody is expected to recognize both reported isoforms (NP_001070671.1; NP_065705.3)

ISO Certification

Manufactured in an ISO 9001:2008 Certified Laboratory.

Applications Tested/Suitable for anti-SENP7 antibody

Peptide ELISA (EIA)

Application Notes for anti-SENP7 antibody

Peptide ELISA: Antibody detection limit dilution 1: 16000.
Western Blot: Preliminary experiments gave an approx 90kDa band in Human Brain (Cerebellum) and Thymus lysates after 0.3ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 112kDa according to NP_001070671.1 and of 120kDa according to NP_065705.3. The 90kDa band was successfully blocked by incubation with the immunizing peptide.

Other Notes

Small volumes of anti-SENP7 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for SENP7. It may not necessarily be applicable to this product.

NCBI GI #

116174736

NCBI GeneID

57337

NCBI Accession #

NP_001070671.1

NCBI Related Accession #

NP_065705.3

UniProt Secondary Accession #

Q7Z3F4; Q96PS5; Q9C0F6; Q9HBT5; A1L3A5; A8MW39; B7WNW8

UniProt Related Accession #

Q9BQF6

GenBank Nucleotide #

NM_001077203.2

NCBI Official Full Name

sentrin-specific protease 7 isoform 2

NCBI Official Synonym Full Names

SUMO1/sentrin specific peptidase 7

NCBI Official Symbol

SENP7

UniProt Protein Name

Sentrin-specific protease 7

UniProt Synonym Protein Names

SUMO-1-specific protease 2; Sentrin/SUMO-specific protease SENP7

Protein Family

Sentrin-specific protease

UniProt Gene Name

SENP7

UniProt Synonym Gene Names

KIAA1707; SSP2; SUSP2

UniProt Entry Name

SENP7_HUMAN

NCBI Protein Information

sentrin-specific protease 7

NCBI Summary for SENP7

The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1; MIM 601912) is required for many cellular processes. SUMO-specific proteases, such as SENP7, process SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also display isopeptidase activity for deconjugation of SUMO-conjugated substrates (Lima and Reverter, 2008 [PubMed 18799455]).[supplied by OMIM, Jun 2009]

UniProt Comments for SENP7

Protease that deconjugates SUMO2 and SUMO3 from targeted proteins, but not SUMO1. Catalyzes the deconjugation of poly-SUMO2 and poly-SUMO3 chains. Has very low efficiency in processing full-length SUMO proteins to their mature forms.

Research Articles on SENP7

1. c-Myc is targeted to the proteasome for degradation in a SUMOylation-dependent manner, regulated by PIAS1, SENP7 and RNF4

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-SENP7 antibody

Disease Name	Pubmed Publications
Nervous System Diseases Antibodies	>1 publications with SENP7 and Nervous System Diseases

Organs/Tissues associated with anti-SENP7 antibody

Organ/Tissue Name	Pubmed Publications
Prostate Antibodies	>1 publications with SENP7 and Prostate
Lung Antibodies	>1 publications with SENP7 and Lung