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Arginase, Type 1/Arg1 (ARG1) Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS421477

MBS421477 is an antibody targeting Arg1. Also known as Goat anti-Arginase, type 1/arg1(rat) Antibody. Reactive in Tested: Mouse, Rat; Expected from sequence similarity: Mouse, Rat. Host: Goat. More details

$450 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Arginase, type 1/arg1, Polyclonal Antibody
Full Product Name
Goat anti-Arginase, type 1/arg1(rat) Antibody
Product Gene Name
anti-Arg1 antibody
Product Synonym Gene Name
ARG1
Product Synonym Names
Arg1; arginase 1; AI type I arginase; arginase 1 liver; Arg1 antibody; arginase 1 antibody; AI type I arginase antibody; arginase 1 liver antibody; Arginase, type 1; Arginase, type 1 / arg1(rat)
Immunogen Sequence
NHKPETDYLK PPK
Clonality
Polyclonal
Host
Goat
Species Reactivity
Tested: Mouse, Rat; Expected from sequence similarity: Mouse, Rat
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration
100ug specific antibody in 200ul (lot specific)
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.
Antibody/Peptide Pairs
Arginase, type 1 / arg1 peptide (MBS426889) is used for blocking the activity of Arginase, type 1/arg1 antibody (MBS421477)
Molecular Weight
34,973 Da
Immunogen
Peptide with sequence C-NHKPETDYLKPPK, from the C Terminus of the protein sequence according to NP_058830.2.
Epitope
C Terminus
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Applications Tested/Suitable for anti-Arg1 antibody
Peptide ELISA (EIA), Western Blot (WB)
Application Notes for anti-Arg1 antibody
Peptide ELISA: Antibody detection limit dilution 1: 1000.
Western Blot: Approx 37kDa band observed in Mouse and Rat Liver lysates (calculated MW of 34.8kDa according to mouse NP_031508.1). Recommended concentration: 1-3ug/ml.

Western Blot (WB) of anti-Arg1 antibody

(0.05ug/ml) staining of Mouse Liver (A) and Rat Liver (B) lysates (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Goat Anti-ARG1 Polyclonal Antibody – Cat# MBS421477

Other Notes

Small volumes of anti-Arg1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Arg1. It may not necessarily be applicable to this product.

NCBI GI #
166091458
NCBI GeneID
29221
NCBI Accession #
NP_058830.2
UniProt Secondary Accession #
Q5BK93
UniProt Related Accession #
P07824
GenBank Nucleotide #
NM_017134.3
NCBI Official Full Name
arginase-1
NCBI Official Synonym Full Names
arginase 1
NCBI Official Symbol
Arg1
UniProt Protein Name
Arginase-1
UniProt Synonym Protein Names
Liver-type arginase; Type I arginase
Protein Family
Arginase
UniProt Gene Name
Arg1
UniProt Entry Name
ARGI1_RAT
NCBI Protein Information
arginase-1

NCBI Summary for Arg1

catalyzes the hydrolysis of arginine to ornithine and urea in arginine metabolism; regulates nitric oxide production [RGD, Feb 2006]

UniProt Comments for Arg1

ARG1: Homotrimer. By arginine or homoarginine. Belongs to the arginase family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.5.3.1; Amino Acid Metabolism - arginine and proline; Hydrolase

Cellular Component: cell soma; cytoplasm; extracellular space; mitochondrial outer membrane; neuron projection; nucleus

Molecular Function: arginase activity; manganese ion binding

Biological Process: aging; arginine catabolic process to ornithine; arginine metabolic process; collagen biosynthetic process; female pregnancy; liver development; lung development; mammary gland involution; maternal process involved in pregnancy; positive regulation of endothelial cell proliferation; response to amine stimulus; response to amino acid stimulus; response to axon injury; response to cadmium ion; response to drug; response to herbicide; response to lipopolysaccharide; response to manganese ion; response to methylmercury; response to peptide hormone stimulus; response to selenium ion; response to steroid hormone stimulus; response to vitamin A; response to vitamin E; response to wounding; response to zinc ion; urea cycle
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Research Articles on Arg1

1. Arg1 expression, which is abundant in polarized M2 cells, is associated with strain/genotype differences from different pathways.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-Arg1 antibody

 Products by Pathway  Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Arginine And Proline Metabolism Pathway antibodies  Arginine And Proline Metabolism Pathway Diagram
 Arginine And Proline Metabolism Pathway antibodies  Arginine And Proline Metabolism Pathway Diagram
 Arginine Biosynthesis Pathway antibodies  Arginine Biosynthesis Pathway Diagram
 Arginine Biosynthesis Pathway antibodies  Arginine Biosynthesis Pathway Diagram
 Biosynthesis Of Amino Acids Pathway antibodies  Biosynthesis Of Amino Acids Pathway Diagram
 Biosynthesis Of Amino Acids Pathway antibodies  Biosynthesis Of Amino Acids Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram

Diseases associated with anti-Arg1 antibody

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >169 publications with Arg1 and Inflammation
 Disease Models, Animal Antibodies  >94 publications with Arg1 and Disease Models, Animal
 Lung Diseases Antibodies  >69 publications with Arg1 and Lung Diseases
 Necrosis Antibodies  >53 publications with Arg1 and Necrosis
 Immune System Diseases Antibodies  >49 publications with Arg1 and Immune System Diseases
 Cardiovascular Diseases Antibodies  >48 publications with Arg1 and Cardiovascular Diseases
 Fibrosis Antibodies  >32 publications with Arg1 and Fibrosis
 Asthma Antibodies  >31 publications with Arg1 and Asthma
 Liver Diseases Antibodies  >28 publications with Arg1 and Liver Diseases
 Neoplasms, Experimental Antibodies  >26 publications with Arg1 and Neoplasms, Experimental

Organs/Tissues associated with anti-Arg1 antibody

 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >103 publications with Arg1 and Lung
 Brain Antibodies  >102 publications with Arg1 and Brain
 Liver Antibodies  >78 publications with Arg1 and Liver
 Small Intestine Antibodies  >41 publications with Arg1 and Small Intestine
 Spleen Antibodies  >34 publications with Arg1 and Spleen
 Eye Antibodies  >28 publications with Arg1 and Eye
 Colon Antibodies  >24 publications with Arg1 and Colon
 Connective Tissue Antibodies  >10 publications with Arg1 and Connective Tissue
 Pancreas Antibodies  >8 publications with Arg1 and Pancreas
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