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B3GNT2 Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS421555

MBS421555 is an antibody targeting B3GNT2. Also known as Goat anti-B3GNT2 Antibody. Reactive in Tested: Human; Expected from sequence similarity: Human, Mouse, Rat. Host: Goat. More details

$450 / 0.1 mg +1 FREE 8GB USB
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Sample Manual Insert View PDF
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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
B3GNT2, Polyclonal Antibody
Full Product Name
Goat anti-B3GNT2 Antibody
Product Gene Name
anti-B3GNT2 antibody
Product Synonym Names
B3GNT2; UDP-GlcNAc: betaGal beta-1,3-N-acetylglucosaminyltransferase 2; B3GN-T1; B3GN-T2; B3GNT; B3GNT-2; B3GNT1; BETA3GNT; UDP-GlcNAc: betaGal beta-1,3-N-acetylglucosaminyltransferase 1; beta-1,3-N-acetylglucosaminyltransferase bGnT-1; beta-1,3-N-a; B3GNT2 antibody; UDP-GlcNAc: betaGal beta-1; 3-N-acetylglucosaminyltransferase 2 antibody; B3GN-T1 antibody; B3GN-T2 antibody; B3GNT antibody; B3GNT-2 antibody; B3GNT1 antibody; BETA3GNT antibody; UDP-GlcNAc: betaGal beta-1; 3-N-acetylglucosaminyltransferase 1 antibody; beta-1; 3-N-acetylglucosaminyltransferase bGnT-1 antibody; beta-1; 3-N-a antibody
Immunogen Sequence
EKHKGFRTFD IE
Clonality
Polyclonal
Host
Goat
Species Reactivity
Tested: Human; Expected from sequence similarity: Human, Mouse, Rat
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.
Antibody/Peptide Pairs
B3GNT2 peptide (MBS426227) is used for blocking the activity of B3GNT2 antibody (MBS421555)
OMIM
605581
Immunogen
Peptide with sequence C-EKHKGFRTFDIE, from the internal region of the protein sequence according to NP_006568.2.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Applications Tested/Suitable for anti-B3GNT2 antibody
Peptide ELISA (EIA), Western Blot (WB)
Application Notes for anti-B3GNT2 antibody
Peptide ELISA: Antibody detection limit dilution 1: 32000.

Western blot: Approx 45kDa band observed in Human Pancreas lysates (calculated MW of 46.0kDa according to NP_006568.2). Recommended concentration: 0.1-0.3µg/ml. An additional band of unknown identity was also consistently observed at 28kDa. This band was successfully blocked by incubation with the immunizing peptide.

Western Blot (WB) of anti-B3GNT2 antibody

(0.1ug/ml) staining of Human Pancreas lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Goat Anti-B3GNT2 Polyclonal Antibody – Cat# MBS421555

Other Notes

Small volumes of anti-B3GNT2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for B3GNT2. It may not necessarily be applicable to this product.

NCBI GI #
9845238
NCBI GeneID
10678
NCBI Accession #
NP_006568.2
UniProt Secondary Accession #
Q54AC1; Q9NQQ9; Q9NQR0; Q9NUT9
UniProt Related Accession #
Q9NY97
GenBank Nucleotide #
NM_006577.5
NCBI Official Full Name
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2
NCBI Official Synonym Full Names
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
NCBI Official Symbol
B3GNT2
NCBI Official Synonym Symbols
B3GNT; BGNT2; B3GNT1; BGnT-2; beta-1; 3-Gn-T1; 3-Gn-T2; B3GN-T2; B3GNT-2; BETA3GNT; beta3Gn-T1; beta3Gn-T2
UniProt Protein Name
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2
UniProt Synonym Protein Names
Beta-1,3-N-acetylglucosaminyltransferase 1; BGnT-1; Beta-1,3-Gn-T1; Beta3Gn-T1; Beta-1,3-galactosyltransferase 7; Beta-1,3-GalTase 7; Beta3Gal-T7; Beta3GalT7; b3Gal-T7; Beta-3-Gx-T7; UDP-Gal:beta-GlcNAc beta-1,3-galactosyltransferase 7; UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2; BGnT-2; Beta-1,3-Gn-T2; Beta-1,3-N-acetylglucosaminyltransferase 2; Beta3Gn-T2; UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase 7
Protein Family
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase
UniProt Gene Name
B3GNT2
UniProt Synonym Gene Names
B3GALT7; B3GNT1; BGnT-1; Beta-1,3-Gn-T1; Beta3Gn-T1; Beta-1,3-GalTase 7; Beta3Gal-T7; Beta3GalT7; b3Gal-T7; BGnT-2; Beta-1,3-Gn-T2; Beta-1,3-N-acetylglucosaminyltransferase 2; Beta3Gn-T2
UniProt Entry Name
B3GN2_HUMAN
NCBI Protein Information
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2

NCBI Summary for B3GNT2

This gene encodes a member of the beta-1,3-N-acetylglucosaminyltransferase family. This enzyme is a type II transmembrane protein. It prefers the substrate of lacto-N-neotetraose, and is involved in the biosynthesis of poly-N-acetyllactosamine chains. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jan 2016]
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UniProt Comments for B3GNT2

B3GNT2: Catalyzes the initiation and elongation of poly-N- acetyllactosamine chains. Belongs to the glycosyltransferase 31 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Glycan Metabolism - glycosphingolipid biosynthesis - lacto and neolacto series; Cell development/differentiation; Glycan Metabolism - keratan sulfate biosynthesis; Transferase; Motility/polarity/chemotaxis; Membrane protein, integral; EC 2.4.1.-

Chromosomal Location of Human Ortholog: 2p15

Cellular Component: Golgi membrane; integral to membrane

Molecular Function: N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity; UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity

Biological Process: axon guidance; keratan sulfate biosynthetic process; O-glycan processing; poly-N-acetyllactosamine biosynthetic process; sensory perception of smell
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Research Articles on B3GNT2

1. High B3GNT2 expression is associated with hepatocellular carcinoma.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-B3GNT2 antibody

 Products by Pathway  Pathway Diagram
 Glycosaminoglycan Biosynthesis - Keratan Sulfate Pathway antibodies  Glycosaminoglycan Biosynthesis - Keratan Sulfate Pathway Diagram
 Glycosaminoglycan Biosynthesis - Keratan Sulfate Pathway antibodies  Glycosaminoglycan Biosynthesis - Keratan Sulfate Pathway Diagram
 Glycosaminoglycan Metabolism Pathway antibodies  Glycosaminoglycan Metabolism Pathway Diagram
 Glycosphingolipid Biosynthesis - Lacto And Neolacto Series Pathway antibodies  Glycosphingolipid Biosynthesis - Lacto And Neolacto Series Pathway Diagram
 Glycosphingolipid Biosynthesis - Lacto And Neolacto Series Pathway antibodies  Glycosphingolipid Biosynthesis - Lacto And Neolacto Series Pathway Diagram
 Keratan Sulfate Biosynthesis Pathway antibodies  Keratan Sulfate Biosynthesis Pathway Diagram
 Keratan Sulfate/keratin Metabolism Pathway antibodies  Keratan Sulfate/keratin Metabolism Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Carbohydrates Pathway antibodies  Metabolism Of Carbohydrates Pathway Diagram

Diseases associated with anti-B3GNT2 antibody

 Disease Name  Pubmed Publications
 Arthritis, Rheumatoid Antibodies  >3 publications with B3GNT2 and Arthritis, Rheumatoid
 Graves Disease Antibodies  >2 publications with B3GNT2 and Graves Disease
 Carcinoma, Hepatocellular Antibodies  >1 publications with B3GNT2 and Carcinoma, Hepatocellular
 Liver Neoplasms Antibodies  >1 publications with B3GNT2 and Liver Neoplasms
 Liver Diseases Antibodies  >1 publications with B3GNT2 and Liver Diseases
 Inflammation Antibodies  >1 publications with B3GNT2 and Inflammation

Organs/Tissues associated with anti-B3GNT2 antibody

 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >1 publications with B3GNT2 and Liver
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