Goat Anti-GLIPR1 Polyclonal Antibody – Cat# MBS421571

GLIPR1 Antibody – Goat Polyclonal

Name: GLIPR1 Antibody; Polyclonal; Goat; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS421571
Price: 305 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS421571

MBS421571 is an antibody targeting GLIPR1. Also known as Goat anti-GLIPR1/RTVP-1 Antibody. Reactive in Expected from sequence similarity: Human. Host: Goat. More details

$305 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

GLIPR1/RTVP-1, Polyclonal Antibody

Full Product Name

Goat anti-GLIPR1/RTVP-1 Antibody

Product Gene Name

anti-GLIPR1 antibody

Product Synonym Gene Name

RTVP-1

Product Synonym Names

GLIPR1; GLI pathogenesis-related 1 (glioma); RTVP-1; CRISP7; GLIPR; RTVP1; glioma pathogenesis-related protein; glioma pathogenesis-related protein 1; related to testis-specific, vespid, and pathogenesis proteins 1; testes-specific vespid and pathogenesis; GLIPR1 antibody; GLI pathogenesis-related 1 (glioma) antibody; RTVP-1 antibody; CRISP7 antibody; GLIPR antibody; RTVP1 antibody; glioma pathogenesis-related protein antibody; glioma pathogenesis-related protein 1 antibody; related to testis-specific; vespid; and pathogenesis proteins 1 antibody; testes-specific vespid and pathogenesis protei antibody; GLIPR1 / RTVP-1

Immunogen Sequence

NRQRDQVKRY YS

Clonality

Polyclonal

Host

Goat

Species Reactivity

Expected from sequence similarity: Human

Form/Format

Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Purity/Purification

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Concentration

100ug specific antibody in 200ul (lot specific)

Preparation and Storage

Aliquot and store at -20 degree C. Minimize freezing and thawing.

Antibody/Peptide Pairs

GLIPR1 / RTVP-1 peptide (MBS426676) is used for blocking the activity of GLIPR1/RTVP-1 antibody (MBS421571)

Molecular Weight

26,919 Da

OMIM

602692

Immunogen

Peptide with sequence C-NRQRDQVKRYYS, from the internal region of the protein sequence according to NP_006842.2.

Epitope

Internal region

ISO Certification

Manufactured in an ISO 9001:2008 Certified Laboratory.

Applications Tested/Suitable for anti-GLIPR1 antibody

Peptide ELISA (EIA)

Application Notes for anti-GLIPR1 antibody

Peptide ELISA: Antibody detection limit dilution 1: 64000.
Western Blot: Preliminary experiments gave an approx 40kDa band in human prostate lysates after 1ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 30.4kDa according to NP_006842.2. The ~40kDa band was successfully blocked by incubation with the immunizing peptide.

Other Notes

Small volumes of anti-GLIPR1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for GLIPR1. It may not necessarily be applicable to this product.

NCBI GI #

110825980

NCBI GeneID

11010

NCBI Accession #

NP_006842.2

UniProt Secondary Accession #

Q15409; Q969K2; A7YET6; F8VUC2

UniProt Related Accession #

P48060

GenBank Nucleotide #

NM_006851.2

NCBI Official Full Name

glioma pathogenesis-related protein 1

NCBI Official Synonym Full Names

GLI pathogenesis related 1

NCBI Official Symbol

GLIPR1

NCBI Official Synonym Symbols

GLIPR; RTVP1; CRISP7

UniProt Protein Name

Glioma pathogenesis-related protein 1

UniProt Synonym Protein Names

Protein RTVP-1

Protein Family

Glioma pathogenesis-related protein

UniProt Gene Name

GLIPR1

UniProt Synonym Gene Names

GLIPR; RTVP1; GliPR 1

UniProt Entry Name

GLIP1_HUMAN

NCBI Protein Information

glioma pathogenesis-related protein 1

NCBI Summary for GLIPR1

This gene encodes a protein with similarity to both the pathogenesis-related protein (PR) superfamily and the cysteine-rich secretory protein (CRISP) family. Increased expression of this gene is associated with myelomocytic differentiation in macrophage and decreased expression of this gene through gene methylation is associated with prostate cancer. The protein has proapoptotic activities in prostate and bladder cancer cells. This gene is a member of a cluster on chromosome 12 containing two other similar genes. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008]

UniProt Comments for GLIPR1

GLIPR1: a protein with similarity to both the pathogenesis-related protein (PR) superfamily and the cysteine-rich secretory protein (CRISP) family. Increased expression of this gene is associated with myelomocytic differentiation in macrophage and decreased expression of this gene through gene methylation is associated with prostate cancer. The protein has proapoptotic activities in prostate and bladder cancer cells. This gene is a member of a cluster on chromosome 12 containing two other similar genes. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008]

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 12q21.2

Cellular Component: extracellular region; integral to membrane; membrane; plasma membrane

Research Articles on GLIPR1

1. Data indicate that combining adenoviral vector-mediated GLIPR1 gene therap (AdGLIPR1) with radiotherapy may achieve additive or synergistic tumor control in selected prostate and bladder tumors.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-GLIPR1 antibody

Products by Pathway	Pathway Diagram
Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway antibodies	Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway Diagram
Metabolism Pathway antibodies	Metabolism Pathway Diagram
Metabolism Of Lipids And Lipoproteins Pathway antibodies	Metabolism Of Lipids And Lipoproteins Pathway Diagram
PPARA Activates Gene Expression Pathway antibodies	PPARA Activates Gene Expression Pathway Diagram
Regulation Of Lipid Metabolism By Peroxisome Proliferator-activated Receptor Alpha (PPARalpha) Pathway antibodies	Regulation Of Lipid Metabolism By Peroxisome Proliferator-activated Receptor Alpha (PPARalpha) Pathway Diagram

Diseases associated with anti-GLIPR1 antibody

Disease Name	Pubmed Publications
Neoplasm Metastasis Antibodies	>4 publications with GLIPR1 and Neoplasm Metastasis
Breast Neoplasms Antibodies	>4 publications with GLIPR1 and Breast Neoplasms
Disease Models, Animal Antibodies	>3 publications with GLIPR1 and Disease Models, Animal
Lung Neoplasms Antibodies	>3 publications with GLIPR1 and Lung Neoplasms
Cell Transformation, Neoplastic Antibodies	>2 publications with GLIPR1 and Cell Transformation, Neoplastic
Neoplasms, Experimental Antibodies	>2 publications with GLIPR1 and Neoplasms, Experimental
Wilms Tumor Antibodies	>2 publications with GLIPR1 and Wilms Tumor
Lung Diseases Antibodies	>1 publications with GLIPR1 and Lung Diseases
Kidney Diseases Antibodies	>1 publications with GLIPR1 and Kidney Diseases
Urinary Bladder Neoplasms Antibodies	>1 publications with GLIPR1 and Urinary Bladder Neoplasms

Organs/Tissues associated with anti-GLIPR1 antibody

Organ/Tissue Name	Pubmed Publications
Prostate Antibodies	>24 publications with GLIPR1 and Prostate
Brain Antibodies	>10 publications with GLIPR1 and Brain
Blood Antibodies	>8 publications with GLIPR1 and Blood
Bone Antibodies	>6 publications with GLIPR1 and Bone
Bone Marrow Antibodies	>5 publications with GLIPR1 and Bone Marrow
Lung Antibodies	>5 publications with GLIPR1 and Lung
Testis Antibodies	>4 publications with GLIPR1 and Testis
Bladder Antibodies	>3 publications with GLIPR1 and Bladder
Kidney Antibodies	>2 publications with GLIPR1 and Kidney
Skin Antibodies	>1 publications with GLIPR1 and Skin