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NPFFR1 Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS421604

MBS421604 is an antibody targeting NPFFR1. Also known as Goat anti-NPFFR1 Antibody. Reactive in Tested: Human; Expected from sequence similarity: Human. Host: Goat. More details

$450 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
NPFFR1, Polyclonal Antibody
Full Product Name
Goat anti-NPFFR1 Antibody
Product Gene Name
anti-NPFFR1 antibody
Product Synonym Names
NPFFR1; neuropeptide FF receptor 1; FLJ10751; GPR147; NPFF1; NPFF1R1; OT7T022; G protein-coupled receptor 147; neuropeptide FF 1; NPFFR1 antibody; neuropeptide FF receptor 1 antibody; FLJ10751 antibody; GPR147 antibody; NPFF1 antibody; NPFF1R1 antibody; OT7T022 antibody; G protein-coupled receptor 147 antibody; neuropeptide FF 1 antibody
Immunogen Sequence
RPSGSHKEAY SERP
Clonality
Polyclonal
Host
Goat
Species Reactivity
Tested: Human; Expected from sequence similarity: Human
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration
100ug specific antibody in 200ul (lot specific)
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.
Antibody/Peptide Pairs
NPFFR1 peptide (MBS425411) is used for blocking the activity of NPFFR1 antibody (MBS421604)
Molecular Weight
47,819 Da
OMIM
607448
Immunogen
Peptide with sequence C-RPSGSHKEAYSERP, from the internal region of the protein sequence according to NP_071429.1.
Epitope
Internal region
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Applications Tested/Suitable for anti-NPFFR1 antibody
Peptide ELISA (EIA), Western Blot (WB)
Application Notes for anti-NPFFR1 antibody
Peptide ELISA: Antibody detection limit dilution 1: 64000.
Western Blot: Approx 48kDa band observed in Human Brain (Cerebellum and Cerebral Cortex) lysates (calculated MW of 47.8kDa according to NP_071429.1). Recommended concentration: 0. 03-0.1ug/ml.

Western Blot (WB) of anti-NPFFR1 antibody

(0. 03ug/ml) staining of Human Brain (Cerebellum) lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Goat Anti-NPFFR1 Polyclonal Antibody – Cat# MBS421604

Other Notes

Small volumes of anti-NPFFR1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for NPFFR1. It may not necessarily be applicable to this product.

NCBI GI #
11545887
NCBI GeneID
64106
NCBI Accession #
NP_071429.1
UniProt Secondary Accession #
Q8NGR0; Q96RN3; A2RRF0
UniProt Related Accession #
Q9GZQ6
GenBank Nucleotide #
NM_022146.4
NCBI Official Full Name
neuropeptide FF receptor 1
NCBI Official Synonym Full Names
neuropeptide FF receptor 1
NCBI Official Symbol
NPFFR1
NCBI Official Synonym Symbols
NPFF1; GPR147; NPFF1R1; OT7T022
UniProt Protein Name
Neuropeptide FF receptor 1
UniProt Synonym Protein Names
G-protein coupled receptor 147; RFamide-related peptide receptor OT7T022
Protein Family
Neuropeptide FF receptor
UniProt Gene Name
NPFFR1
UniProt Synonym Gene Names
GPR147; NPFF1
UniProt Entry Name
NPFF1_HUMAN
NCBI Protein Information
neuropeptide FF receptor 1

UniProt Comments for NPFFR1

NPFFR1: Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. Belongs to the G-protein coupled receptor 1 family.

Protein type: Receptor, GPCR; GPCR, family 1; Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 10q21-q22

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: G-protein coupled receptor activity; neuropeptide receptor activity; peptide binding

Biological Process: cellular response to hormone stimulus; neuropeptide signaling pathway; synaptic transmission
Show more

Research Articles on NPFFR1

1. RFRP-3/GPR147 may play secondary, modulatory roles on the regulation of pubertal development; a restraining modulatory effect of the NPVF p.I71_K72 variant on the activation of the gonadotrophic axis cannot be ruled out

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-NPFFR1 antibody

 Products by Pathway  Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 G Alpha (q) Signalling Events Pathway antibodies  G Alpha (q) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 GPCRs, Class A Rhodopsin-like Pathway antibodies  GPCRs, Class A Rhodopsin-like Pathway Diagram
 Gastrin-CREB Signalling Pathway Via PKC And MAPK antibodies  Gastrin-CREB Signalling Pathway Via PKC And MAPK Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Orexin And Neuropeptides FF And QRFP Bind To Their Respective Receptors Pathway antibodies  Orexin And Neuropeptides FF And QRFP Bind To Their Respective Receptors Pathway Diagram
 Peptide Ligand-binding Receptors Pathway antibodies  Peptide Ligand-binding Receptors Pathway Diagram

Organs/Tissues associated with anti-NPFFR1 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >4 publications with NPFFR1 and Brain
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