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RASSF8 Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS421615

MBS421615 is an antibody targeting RASSF8. Also known as Goat anti-RASSF8 Antibody. Reactive in Tested: Human; Expected from sequence similarity: Human, Mouse, Cow. Host: Goat. More details

$450 / 0.1 mg +1 FREE 8GB USB
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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
RASSF8, Polyclonal Antibody
Full Product Name
Goat anti-RASSF8 Antibody
Product Gene Name
Product Synonym Names
RASSF8; Ras association (RalGDS/AF-6) domain family 8; C12orf2; HoJ-1; carcinoma associated HOJ-1; RASSF8 antibody; Ras association (RalGDS/AF-6) domain family 8 antibody; C12orf2 antibody; HoJ-1 antibody; carcinoma associated HOJ-1 antibody
Immunogen Sequence
RDTERHLAPH EN
Clonality
Polyclonal
Host
Goat
Species Reactivity
Tested: Human; Expected from sequence similarity: Human, Mouse, Cow
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration
100ug specific antibody in 200ul (lot specific)
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.
Antibody/Peptide Pairs
RASSF8 peptide (MBS426279) is used for blocking the activity of RASSF8 antibody (MBS421615)
Molecular Weight
45,446 Da
OMIM
608180
Immunogen
Peptide with sequence C-RDTERHLAPHEN, from the internal region of the protein sequence according to NP_009142.2.
Epitope
Internal region
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Applications Tested/Suitable for anti-RASSF8 antibody
Peptide ELISA (EIA), Western Blot (WB)
Application Notes for anti-RASSF8 antibody
Peptide ELISA: Antibody detection limit dilution 1: 128000.
Western Blot: Approx 40-45kDa band observed in Human Testis lysates (calculated MW of 45.4kDa according to NP_009142.2). Recommended concentration: 0.3-1ug/ml.

Western Blot (WB) of anti-RASSF8 antibody

(0.3ug/ml) staining of Human Testis lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Goat Anti-RASSF8 Polyclonal Antibody – Cat# MBS421615

Other Notes

Small volumes of anti-RASSF8 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for RASSF8. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
ras association domain-containing protein 8 isoform b
NCBI Official Synonym Full Names
Ras association domain family member 8
NCBI Official Symbol
RASSF8
NCBI Official Synonym Symbols
HOJ1; C12orf2
UniProt Protein Name
Ras association domain-containing protein 8
UniProt Synonym Protein Names
Carcinoma-associated protein HOJ-1
UniProt Gene Name
RASSF8
UniProt Synonym Gene Names
C12orf2
UniProt Entry Name
RASF8_HUMAN
NCBI Protein Information
ras association domain-containing protein 8

NCBI Summary for RASSF8

This gene encodes a member of the Ras-assocation domain family (RASSF) of tumor suppressor proteins. This gene is essential for maintaining adherens junction function in epithelial cells and has a role in epithelial cell migration. It is a lung tumor suppressor gene candidate. A chromosomal translocation t(12;22)(p11.2;q13.3) leading to the fusion of this gene and the FBLN1 gene is found in a complex type of synpolydactyly. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011]
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UniProt Comments for RASSF8

RASSF8: A chromosomal aberration involving RASSF8 is found in a complex type of synpolydactyly referred to as 3/3-prime/4 synpolydactyly associated with metacarpal and metatarsal synostoses. Reciprocal translocation t(12;22)(p11.2;q13.3) with C12orf2. 2 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 12p12.3

Biological Process: signal transduction
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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