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LPP Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS421637

MBS421637 is an antibody targeting LPP. Also known as Goat anti-LPP Antibody. Reactive in Tested: Human; Expected from sequence similarity: Human, Dog, Cow. Host: Goat. More details

$450 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
LPP, Polyclonal Antibody
Full Product Name
Goat anti-LPP Antibody
Product Gene Name
Product Synonym Names
LPP; LIM domain containing preferred translocation partner in lipoma; LIM domain-containing preferred translocation partner in lipoma; LIM protein; Lipoma-preferred partner; LPP antibody; LIM domain containing preferred translocation partner in lipoma antibody; LIM domain-containing preferred translocation partner in lipoma antibody; Lipoma-preferred partner antibody
Immunogen Sequence
RNDSDPTYGQ QGHP
Clonality
Polyclonal
Host
Goat
Species Reactivity
Tested: Human; Expected from sequence similarity: Human, Dog, Cow
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration
100ug specific antibody in 200ul (lot specific)
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.
Antibody/Peptide Pairs
LPP peptide (MBS426471) is used for blocking the activity of LPP antibody (MBS421637)
Molecular Weight
65,746 Da
OMIM
600700
Immunogen
Peptide with sequence C-RNDSDPTYGQQGHP, from the internal region of the protein sequence according to NP_005569.1.
Epitope
Internal region
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Applications Tested/Suitable for anti-LPP antibody
Peptide ELISA (EIA), Western Blot (WB)
Application Notes for anti-LPP antibody
Peptide ELISA: Antibody detection limit dilution 1: 16000.
Western Blot: Approx 85kDa band observed in Human Placenta lysates and in lysates of cell line HepG2 (calculated MW of 65.7kDa according to NP_005569.1). The observed molecular weight corresponds to earlier findings with different antibodies from other commercial sources. Recommended concentration: 0.1-0.3ug/ml.

Western Blot (WB) of anti-LPP antibody

(0.1ug/ml) staining of HepG2 lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Goat Anti-LPP Polyclonal Antibody – Cat# MBS421637

Other Notes

Small volumes of anti-LPP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for LPP. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
lipoma-preferred partner isoform a
NCBI Official Synonym Full Names
LIM domain containing preferred translocation partner in lipoma
NCBI Official Symbol
LPP
UniProt Protein Name
Lipoma-preferred partner
UniProt Synonym Protein Names
LIM domain-containing preferred translocation partner in lipoma
UniProt Gene Name
LPP
UniProt Entry Name
LPP_HUMAN
NCBI Protein Information
lipoma-preferred partner

NCBI Summary for LPP

This gene encodes a member of a subfamily of LIM domain proteins that are characterized by an N-terminal proline-rich region and three C-terminal LIM domains. The encoded protein localizes to the cell periphery in focal adhesions and may be involved in cell-cell adhesion and cell motility. This protein also shuttles through the nucleus and may function as a transcriptional co-activator. This gene is located at the junction of certain disease-related chromosomal translocations, which result in the expression of chimeric proteins that may promote tumor growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
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UniProt Comments for LPP

LPP: a LIM domain-containing that may function in focal adhesion and nuclear targeting.

Protein type: Adaptor/scaffold; Cytoskeletal; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 3q28

Cellular Component: cytoplasm; focal adhesion; nucleus; plasma membrane

Molecular Function: protein binding; zinc ion binding

Biological Process: cell adhesion

Disease: Leukemia, Acute Myeloid
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-LPP antibody

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