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Endothelial Lipase (LIPG) Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS421806

MBS421806 is an antibody targeting LIPG. Also known as Goat anti-Endothelial lipase Antibody. Reactive in Tested: Human; Expected from sequence similarity: Human. Host: Goat. More details

$450 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Endothelial lipase (LIPG), Polyclonal Antibody
Full Product Name
Goat anti-Endothelial lipase Antibody
Product Gene Name
anti-LIPG antibody
Product Synonym Names
endothelial lipase; lipase, endothelial; LIPG; EDL; EL; PRO719; endothelial cell-derived lipase; lipoprotein lipase H; endothelial lipase antibody; lipase; endothelial antibody; LIPG antibody; EDL antibody; EL antibody; PRO719 antibody; endothelial cell-derived lipase antibody; lipoprotein lipase H antibody; Endothelial lipase; Endothelial lipase
Immunogen Sequence
RFNLRTSKDP EHEG
Clonality
Polyclonal
Host
Goat
Species Reactivity
Tested: Human; Expected from sequence similarity: Human
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration
100ug specific antibody in 200ul (lot specific)
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.
Antibody/Peptide Pairs
Endothelial lipase peptide (MBS426693) is used for blocking the activity of Endothelial lipase antibody (MBS421806)
Molecular Weight
39,362 Da
OMIM
603684
Immunogen
Peptide with sequence C-RFNLRTSKDPEHEG, from the internal region of the protein sequence according to NP_006024.1.
Epitope
Internal region
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Applications Tested/Suitable for anti-LIPG antibody
Peptide ELISA (EIA), Western Blot (WB)
Application Notes for anti-LIPG antibody
Peptide ELISA: Antibody detection limit dilution 1: 16000.

Western Blot (WB) of anti-LIPG antibody

(0.3ug/ml) staining of Human Liver lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Goat Anti-LIPG Polyclonal Antibody – Cat# MBS421806

Other Notes

Small volumes of anti-LIPG antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for LIPG. It may not necessarily be applicable to this product.

NCBI GI #
5174497
NCBI GeneID
9388
NCBI Accession #
NP_006024.1
UniProt Secondary Accession #
Q6P9C8; Q6UW82; B0LPG6
UniProt Related Accession #
Q9Y5X9
GenBank Nucleotide #
NM_006033.3
NCBI Official Full Name
endothelial lipase isoform 1
NCBI Official Synonym Full Names
lipase G, endothelial type
NCBI Official Symbol
LIPG
NCBI Official Synonym Symbols
EL; EDL; PRO719
UniProt Protein Name
Endothelial lipase
UniProt Synonym Protein Names
Endothelial cell-derived lipase; EDL; EL
Protein Family
Endothelial lipase
UniProt Gene Name
LIPG
UniProt Synonym Gene Names
EDL; EL
UniProt Entry Name
LIPE_HUMAN
NCBI Protein Information
endothelial lipase

NCBI Summary for LIPG

The protein encoded by this gene has substantial phospholipase activity and may be involved in lipoprotein metabolism and vascular biology. This protein is designated a member of the TG lipase family by its sequence and characteristic lid region which provides substrate specificity for enzymes of the TG lipase family. [provided by RefSeq, Jul 2008]
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UniProt Comments for LIPG

LIPG: Has phospholipase and triglyceride lipase activities. Hydrolyzes high density lipoproteins (HDL) more efficiently than other lipoproteins. Binds heparin. Belongs to the AB hydrolase superfamily. Lipase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Phospholipase; EC 3.1.1.3; Secreted, signal peptide; Secreted; Lipid Metabolism - glycerolipid

Chromosomal Location of Human Ortholog: 18q21.1

Cellular Component: cell surface; early endosome; extracellular region; extracellular space; Golgi apparatus

Molecular Function: heparin binding; lipoprotein lipase activity; phospholipase A1 activity; phospholipase activity

Biological Process: cell proliferation; cholesterol homeostasis; lipid digestion; lipid metabolic process; phospholipid catabolic process; phospholipid homeostasis; positive regulation of cholesterol transport; regulation of lipoprotein metabolic process; response to nutrient; reverse cholesterol transport
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Research Articles on LIPG

1. results suggested that the SNP -384A/C in the LIPG gene may be associated with risk for coronary artery disease(CAD)and the LIPG gene may play a role in CAD in the Han Chinese

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-LIPG antibody

 Products by Pathway  Pathway Diagram
 Acylglycerol Degradation Pathway antibodies  Acylglycerol Degradation Pathway Diagram
 Acylglycerol Degradation Pathway antibodies  Acylglycerol Degradation Pathway Diagram
 Digestion Of Dietary Lipid Pathway antibodies  Digestion Of Dietary Lipid Pathway Diagram
 Glycerolipid Metabolism Pathway antibodies  Glycerolipid Metabolism Pathway Diagram
 Glycerolipid Metabolism Pathway antibodies  Glycerolipid Metabolism Pathway Diagram
 Lipid Digestion, Mobilization, And Transport Pathway antibodies  Lipid Digestion, Mobilization, And Transport Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Lipids And Lipoproteins Pathway antibodies  Metabolism Of Lipids And Lipoproteins Pathway Diagram
 Triacylglycerol Degradation Pathway antibodies  Triacylglycerol Degradation Pathway Diagram

Diseases associated with anti-LIPG antibody

 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >81 publications with LIPG and Cardiovascular Diseases
 Atherosclerosis Antibodies  >58 publications with LIPG and Atherosclerosis
 Inflammation Antibodies  >27 publications with LIPG and Inflammation
 Dyslipidemias Antibodies  >20 publications with LIPG and Dyslipidemias
 Hypertension Antibodies  >16 publications with LIPG and Hypertension
 Obesity Antibodies  >13 publications with LIPG and Obesity
 Necrosis Antibodies  >11 publications with LIPG and Necrosis
 Fatty Liver Antibodies  >8 publications with LIPG and Fatty Liver
 Insulin Resistance Antibodies  >8 publications with LIPG and Insulin Resistance
 Liver Diseases Antibodies  >7 publications with LIPG and Liver Diseases

Organs/Tissues associated with anti-LIPG antibody

 Organ/Tissue Name  Pubmed Publications
 Placenta Antibodies  >11 publications with LIPG and Placenta
 Muscle Antibodies  >10 publications with LIPG and Muscle
 Kidney Antibodies  >9 publications with LIPG and Kidney
 Brain Antibodies  >6 publications with LIPG and Brain
 Embryonic Tissue Antibodies  >6 publications with LIPG and Embryonic Tissue
 Testis Antibodies  >5 publications with LIPG and Testis
 Ovary Antibodies  >5 publications with LIPG and Ovary
 Thyroid Antibodies  >2 publications with LIPG and Thyroid
 Pancreas Antibodies  >2 publications with LIPG and Pancreas
 Intestine Antibodies  >2 publications with LIPG and Intestine
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