Goat Anti-TAF7L Polyclonal Antibody – Cat# MBS421860

(1ug/ml) staining of Human Testis lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

TAF7L Antibody – Goat Polyclonal

Name: TAF7L Antibody; Polyclonal; Goat; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS421860
Price: 450 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS421860

MBS421860 is an antibody targeting TAF7L. Also known as Goat anti-TAF7L Antibody. Reactive in Tested: Human; Expected from sequence similarity: Human. Host: Goat. More details

$450 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

TAF7L, Polyclonal Antibody

Full Product Name

Goat anti-TAF7L Antibody

Product Gene Name

anti-TAF7L antibody

Product Synonym Names

TAF7L; TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa; FLJ23157; TAF2Q; dJ738A13.1; OTTHUMP00000023675; TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50 kD; TATA box binding protein (T; TAF7L antibody; TAF7-like RNA polymerase II; TATA box binding protein (TBP)-associated factor; 50kDa antibody; FLJ23157 antibody; TAF2Q antibody; dJ738A13.1 antibody; OTTHUMP00000023675 antibody; TAF7-like RNA polymerase II; TATA box binding protein (TBP)-associated factor; 50 kD antibody; TATA box binding protein (TBP)-associated factor; RNA polymerase II; Q antibody; TATA box binding protein-associated factor; RNA polymerase II; Q antibody; TBP-associated factor; RNA polymerase II; Q antibody

Immunogen Sequence

NHFQSVLEQL ELQEK

Clonality

Polyclonal

Host

Goat

Species Reactivity

Tested: Human; Expected from sequence similarity: Human

Form/Format

Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Purity/Purification

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Concentration

100ug specific antibody in 200ul (lot specific)

Preparation and Storage

Aliquot and store at -20 degree C. Minimize freezing and thawing.

Antibody/Peptide Pairs

TAF7L peptide (MBS425203) is used for blocking the activity of TAF7L antibody (MBS421860)

Molecular Weight

34,726 Da

OMIM

300314

Immunogen

Peptide with sequence C-NHFQSVLEQLELQEK, from the internal region (near C Terminus) of the protein sequence according to NP_079161.2.

Epitope

Internal region (near C Terminus)

ISO Certification

Manufactured in an ISO 9001:2008 Certified Laboratory.

Applications Tested/Suitable for anti-TAF7L antibody

Peptide ELISA (EIA), Western Blot (WB)

Application Notes for anti-TAF7L antibody

Peptide ELISA: Antibody detection limit dilution 1: 16000.
Western Blot: Approx 40kDa band observed in Human Testis lysates (calculated MW of 52.6kDa according to NP_079161.2). The observed molecular weight corresponds to earlier findings with different antibodies from other commercial sources. Recommended concentration: 0.3-1ug/ml.

Other Notes

Small volumes of anti-TAF7L antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for TAF7L. It may not necessarily be applicable to this product.

NCBI GI #

51477718

NCBI GeneID

54457

NCBI Accession #

NP_079161.2

UniProt Secondary Accession #

Q5H9L6; Q86XI4; Q9BXU5; Q9H5R0

UniProt Related Accession #

Q5H9L4

GenBank Nucleotide #

NM_024885.2

NCBI Official Full Name

TATA box binding protein-associated factor, RNA polymerase II, Q

NCBI Official Synonym Full Names

TATA-box binding protein associated factor 7 like

NCBI Official Symbol

TAF7L

NCBI Official Synonym Symbols

CT40; TAF2Q

UniProt Protein Name

Transcription initiation factor TFIID subunit 7-like

UniProt Synonym Protein Names

Cancer/testis antigen 40; CT40; RNA polymerase II TBP-associated factor subunit Q; TATA box-binding protein-associated factor 50 kDa; Transcription initiation factor TFIID 50 kDa subunit

Protein Family

Transcription initiation factor

UniProt Gene Name

TAF7L

UniProt Synonym Gene Names

TAF2Q; CT40

UniProt Entry Name

TAF7L_HUMAN

NCBI Protein Information

transcription initiation factor TFIID subunit 7-like

NCBI Summary for TAF7L

This gene is similar to a mouse gene that encodes a TATA box binding protein-associated factor, and shows testis-specific expression. The encoded protein could be a spermatogenesis-specific component of the DNA-binding general transcription factor complex TFIID. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]

UniProt Comments for TAF7L

TAF7L: Probably functions as a spermatogensis-specific component of the DNA-binding general transcription factor complex TFIID, a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. May play a role in spermatogenesis. Belongs to the TAF7 family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Cancer Testis Antigen (CTA); DNA-binding

Chromosomal Location of Human Ortholog: Xq22.1

Cellular Component: cytoplasm; transcription factor TFIID complex

Molecular Function: histone acetyltransferase binding; transcription coactivator activity; transcription factor binding

Biological Process: cell differentiation; multicellular organismal development; regulation of transcription from RNA polymerase II promoter; spermatogenesis; transcriptional preinitiation complex assembly

Research Articles on TAF7L

1. Over-expression of TAF7L was observed in breast tumor cell lines.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-TAF7L antibody

Products by Pathway	Pathway Diagram
Basal Transcription Factors Pathway antibodies	Basal Transcription Factors Pathway Diagram
Basal Transcription Factors Pathway antibodies	Basal Transcription Factors Pathway Diagram

Diseases associated with anti-TAF7L antibody

Disease Name	Pubmed Publications
Infertility, Male Antibodies	>7 publications with TAF7L and Infertility, Male
Neurobehavioral Manifestations Antibodies	>1 publications with TAF7L and Neurobehavioral Manifestations
Oligospermia Antibodies	>1 publications with TAF7L and Oligospermia
Abnormalities, Multiple Antibodies	>1 publications with TAF7L and Abnormalities, Multiple
Breast Neoplasms Antibodies	>1 publications with TAF7L and Breast Neoplasms

Organs/Tissues associated with anti-TAF7L antibody

Organ/Tissue Name	Pubmed Publications
Testis Antibodies	>12 publications with TAF7L and Testis