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IP6K3 Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS421870

MBS421870 is an antibody targeting IP6K3. Also known as Goat anti-IP6K3 Antibody. Reactive in Expected from sequence similarity: Human, Mouse, Rat, Dog, Cow. Host: Goat. More details

$450 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
IP6K3, Polyclonal Antibody
Full Product Name
Goat anti-IP6K3 Antibody
Product Gene Name
anti-IP6K3 antibody
Product Synonym Names
IP6K3; inositol hexakisphosphate kinase 3; IHPK3; INSP6K3; MGC102928; ATP: 1D-myo-inositol-hexakisphosphate phosphotransferase; InsP6 kinase 3; OTTHUMP00000016212; inositol hexaphosphate kinase 3; IP6K3 antibody; inositol hexakisphosphate kinase 3 antibody; IHPK3 antibody; INSP6K3 antibody; MGC102928 antibody; ATP: 1D-myo-inositol-hexakisphosphate phosphotransferase antibody; InsP6 kinase 3 antibody; OTTHUMP00000016212 antibody; inositol hexaphosphate kinase 3 antibody
Immunogen Sequence
RLCSEYPENK RHR
Clonality
Polyclonal
Host
Goat
Species Reactivity
Expected from sequence similarity: Human, Mouse, Rat, Dog, Cow
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration
100ug specific antibody in 200ul (lot specific)
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.
Antibody/Peptide Pairs
IP6K3 peptide (MBS425152) is used for blocking the activity of IP6K3 antibody (MBS421870)
Molecular Weight
46,417 Da
OMIM
606993
Immunogen
Peptide with sequence RLCSEYPENKRHR, from the internal region of the protein sequence according to NP_473452.2.
Epitope
Internal region
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Applications Tested/Suitable for anti-IP6K3 antibody
Peptide ELISA (EIA)
Application Notes for anti-IP6K3 antibody
Peptide ELISA: Antibody detection limit dilution 1: 32000.
Western Blot: Preliminary experiments gave an approx 37kDa band in Human Brain (Cerebral Cortex and Hippocampus) and Mouse Brain lysates after 0.5ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 46.4kDa according to NP_473452.2. The 37kDa band was successfully blocked by incubation with the immunizing peptide.

Other Notes

Small volumes of anti-IP6K3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for IP6K3. It may not necessarily be applicable to this product.

NCBI GI #
55769530
NCBI GeneID
117283
NCBI Accession #
NP_473452.2
UniProt Secondary Accession #
Q96MQ9
UniProt Related Accession #
Q96PC2
GenBank Nucleotide #
NM_054111.4
NCBI Official Full Name
inositol hexakisphosphate kinase 3
NCBI Official Synonym Full Names
inositol hexakisphosphate kinase 3
NCBI Official Symbol
IP6K3
NCBI Official Synonym Symbols
IHPK3; INSP6K3
UniProt Protein Name
Inositol hexakisphosphate kinase 3
UniProt Synonym Protein Names
Inositol hexaphosphate kinase 3
Protein Family
Inositol hexakisphosphate kinase
UniProt Gene Name
IP6K3
UniProt Synonym Gene Names
IHPK3; InsP6 kinase 3
UniProt Entry Name
IP6K3_HUMAN
NCBI Protein Information
inositol hexakisphosphate kinase 3

NCBI Summary for IP6K3

This gene encodes a protein that belongs to the inositol phosphokinase (IPK) family. This protein is likely responsible for the conversion of inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). It may also convert 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4. Alternative splicing results in multiple transcript variants encoding the same protein.[provided by RefSeq, Dec 2008]
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UniProt Comments for IP6K3

IHPK3: Converts inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). Converts 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4. Belongs to the inositol phosphokinase (IPK) family.

Protein type: EC 2.7.4.21; Kinase, other; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 6p21.31

Cellular Component: cytoplasm; cytosol; nucleus

Molecular Function: ATP binding; inositol 1,3,4,5,6-pentakisphosphate kinase activity; inositol heptakisphosphate kinase activity; inositol hexakisphosphate 5-kinase activity; inositol hexakisphosphate 6-kinase activity; inositol hexakisphosphate kinase activity; inositol trisphosphate 3-kinase activity

Biological Process: inositol phosphate biosynthetic process; inositol phosphate metabolic process; phosphatidylinositol metabolic process; protein amino acid phosphorylation
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Research Articles on IP6K3

1. Observational study of gene-disease association. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-IP6K3 antibody

 Products by Pathway  Pathway Diagram
 Inositol Phosphate Metabolism Pathway antibodies  Inositol Phosphate Metabolism Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Phosphatidylinositol Signaling System Pathway antibodies  Phosphatidylinositol Signaling System Pathway Diagram
 Phosphatidylinositol Signaling System Pathway antibodies  Phosphatidylinositol Signaling System Pathway Diagram
 Synthesis Of Pyrophosphates In The Cytosol Pathway antibodies  Synthesis Of Pyrophosphates In The Cytosol Pathway Diagram
 Inositol Pyrophosphates Biosynthesis Pathway antibodies  Inositol Pyrophosphates Biosynthesis Pathway Diagram
 Inositol Pyrophosphates Biosynthesis Pathway antibodies  Inositol Pyrophosphates Biosynthesis Pathway Diagram
 Superpathway Of Inositol Phosphate Compounds antibodies  Superpathway Of Inositol Phosphate Compounds Diagram

Organs/Tissues associated with anti-IP6K3 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >1 publications with IP6K3 and Brain
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