Goat Anti-RARS Polyclonal Antibody – Cat# MBS421905

(1ug/ml) staining of HepG2 lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

RARS Antibody – Goat Polyclonal

Name: RARS Antibody; Polyclonal; Goat; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS421905
Price: 450 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS421905

MBS421905 is an antibody targeting RARS. Also known as Goat anti-RARS Antibody. Reactive in Tested: Human; Expected from sequence similarity: Human, Mouse, Rat, Cow. Host: Goat. More details

$450 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

RARS, Polyclonal Antibody

Full Product Name

Goat anti-RARS Antibody

Product Gene Name

anti-RARS antibody

Product Synonym Names

RARS; arginyl-tRNA synthetase; ArgRS; DALRD1; MGC8641; arginine tRNA ligase 1, cytoplasmic; arginine tRNA ligase 1; cytoplasmic antibody; arginyl-tRNA synthetase antibody; ArgRS antibody; DALRD1 antibody; MGC8641 antibody; RARS antibody

Immunogen Sequence

SLQAERNKPT KN

Clonality

Polyclonal

Host

Goat

Species Reactivity

Tested: Human; Expected from sequence similarity: Human, Mouse, Rat, Cow

Form/Format

Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Purity/Purification

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Concentration

100ug specific antibody in 200ul (lot specific)

Preparation and Storage

Aliquot and store at -20 degree C. Minimize freezing and thawing.

Antibody/Peptide Pairs

RARS peptide (MBS426136) is used for blocking the activity of RARS antibody (MBS421905)

Molecular Weight

67,140 Da

OMIM

107820

Immunogen

Peptide with sequence C-SLQAERNKPTKN, from the internal region of the protein sequence according to NP_002878.2.

Epitope

Internal region

ISO Certification

Manufactured in an ISO 9001:2008 Certified Laboratory.

Applications Tested/Suitable for anti-RARS antibody

Peptide ELISA (EIA), Western Blot (WB)

Application Notes for anti-RARS antibody

Peptide ELISA: Antibody detection limit dilution 1: 128000.
Western Blot: Approx 75kDa band observed in lysates of HeLa and HepG2 (calculated MW of 75.4kDa according to NP_002878.2). Recommended concentration: 1-3ug/ml.

Other Notes

Small volumes of anti-RARS antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for RARS. It may not necessarily be applicable to this product.

NCBI GI #

15149476

NCBI GeneID

5917

NCBI Accession #

NP_002878.2

UniProt Secondary Accession #

Q53GY4; Q9BWA1; B2RBS9

UniProt Related Accession #

P54136

GenBank Nucleotide #

NM_002887.3

NCBI Official Full Name

arginine--tRNA ligase, cytoplasmic

NCBI Official Synonym Full Names

arginyl-tRNA synthetase

NCBI Official Symbol

RARS

NCBI Official Synonym Symbols

HLD9; ArgRS; DALRD1

UniProt Protein Name

Arginine--tRNA ligase, cytoplasmic

UniProt Synonym Protein Names

Arginyl-tRNA synthetase; ArgRS

Protein Family

Arginine--tRNA ligase

UniProt Gene Name

RARS

UniProt Synonym Gene Names

ArgRS

UniProt Entry Name

SYRC_HUMAN

NCBI Protein Information

arginine--tRNA ligase, cytoplasmic

NCBI Summary for RARS

Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Arginyl-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family. [provided by RefSeq, Jul 2008]

UniProt Comments for RARS

RARS: Forms part of a macromolecular complex that catalyzes the attachment of specific amino acids to cognate tRNAs during protein synthesis. Modulates the secretion of AIMP1 and may be involved in generation of the inflammatory cytokine EMAP2 from AIMP1. Belongs to the class-I aminoacyl-tRNA synthetase family. 2 isoforms of the human protein are produced by alternative initiation.

Protein type: Mitochondrial; Translation; EC 6.1.1.19; RNA-binding; Ligase

Chromosomal Location of Human Ortholog: 5q35.1

Cellular Component: aminoacyl-tRNA synthetase multienzyme complex; cytoplasm; cytosol; membrane; mitochondrion; nucleoplasm

Molecular Function: arginine-tRNA ligase activity; ATP binding; protein binding; tRNA binding

Biological Process: arginyl-tRNA aminoacylation; tRNA aminoacylation for protein translation

Disease: Leukodystrophy, Hypomyelinating, 9

Research Articles on RARS

1. Data indicate that the N terminus of Pro-EMAP II binds to its C terminus, arginyl-tRNA synthetase, and the neurofilament light subunit.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-RARS antibody

Reference Product	PubMed Publications
LARS antibody	>4 publications with RARS and LARS
MARS antibody	>4 publications with RARS and MARS
QARS antibody	>4 publications with RARS and QARS
DARS antibody	>3 publications with RARS and DARS
KARS antibody	>3 publications with RARS and KARS
EPRS antibody	>3 publications with RARS and EPRS
IARS antibody	>2 publications with RARS and IARS
AIMP1 antibody	>2 publications with RARS and AIMP1
AIMP2 antibody	>1 publications with RARS and AIMP2

Pathways associated with anti-RARS antibody

Products by Pathway	Pathway Diagram
Aminoacyl-tRNA Biosynthesis Pathway antibodies	Aminoacyl-tRNA Biosynthesis Pathway Diagram
Aminoacyl-tRNA Biosynthesis Pathway antibodies	Aminoacyl-tRNA Biosynthesis Pathway Diagram
Aminoacyl-tRNA Biosynthesis, Eukaryotes Pathway antibodies	Aminoacyl-tRNA Biosynthesis, Eukaryotes Pathway Diagram
Aminoacyl-tRNA Biosynthesis, Eukaryotes Pathway antibodies	Aminoacyl-tRNA Biosynthesis, Eukaryotes Pathway Diagram
Cytosolic TRNA Aminoacylation Pathway antibodies	Cytosolic TRNA Aminoacylation Pathway Diagram
Gene Expression Pathway antibodies	Gene Expression Pathway Diagram
Metabolism Pathway antibodies	Metabolism Pathway Diagram
Metabolism Of Amino Acids And Derivatives Pathway antibodies	Metabolism Of Amino Acids And Derivatives Pathway Diagram
SeMet Incorporation Into Proteins Pathway antibodies	SeMet Incorporation Into Proteins Pathway Diagram
Selenoamino Acid Metabolism Pathway antibodies	Selenoamino Acid Metabolism Pathway Diagram

Diseases associated with anti-RARS antibody

Disease Name	Pubmed Publications
Carcinoma Antibodies	>171 publications with RARS and Carcinoma
Breast Neoplasms Antibodies	>66 publications with RARS and Breast Neoplasms
Cell Transformation, Neoplastic Antibodies	>39 publications with RARS and Cell Transformation, Neoplastic
Adenocarcinoma Antibodies	>35 publications with RARS and Adenocarcinoma
Inflammation Antibodies	>28 publications with RARS and Inflammation
Hyperplasia Antibodies	>24 publications with RARS and Hyperplasia
Necrosis Antibodies	>24 publications with RARS and Necrosis
Cardiovascular Diseases Antibodies	>23 publications with RARS and Cardiovascular Diseases
Neoplasms, Experimental Antibodies	>21 publications with RARS and Neoplasms, Experimental
Precancerous Conditions Antibodies	>17 publications with RARS and Precancerous Conditions

Organs/Tissues associated with anti-RARS antibody

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>323 publications with RARS and Blood
Bone Antibodies	>288 publications with RARS and Bone
Bone Marrow Antibodies	>242 publications with RARS and Bone Marrow
Lung Antibodies	>159 publications with RARS and Lung
Thyroid Antibodies	>112 publications with RARS and Thyroid
Skin Antibodies	>94 publications with RARS and Skin
Embryonic Tissue Antibodies	>79 publications with RARS and Embryonic Tissue
Brain Antibodies	>79 publications with RARS and Brain
Liver Antibodies	>71 publications with RARS and Liver
Muscle Antibodies	>56 publications with RARS and Muscle