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TRAF3IP1 Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS421944

MBS421944 is an antibody targeting TRAF3IP1. Also known as Goat anti-TRAF3IP1 Antibody. Reactive in Expected from sequence similarity: Human. Host: Goat. More details

$305 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
TRAF3IP1, Polyclonal Antibody
Full Product Name
Goat anti-TRAF3IP1 Antibody
Product Gene Name
anti-TRAF3IP1 antibody
Product Synonym Names
TRAF3IP1; TNF receptor-associated factor 3 interacting protein 1; DKFZp434F124; MIP-T3; MIPT3; interleukin 13 receptor alpha 1-binding protein-1; microtubule interacting protein that associates with TRAF3; TRAF3IP1 antibody; TNF receptor-associated factor 3 interacting protein 1 antibody; DKFZp434F124 antibody; MIP-T3 antibody; MIPT3 antibody; interleukin 13 receptor alpha 1-binding protein-1 antibody; microtubule interacting protein that associates with TRAF3 antibody
Immunogen Sequence
RCENIQPNPT EKQK
Clonality
Polyclonal
Host
Goat
Species Reactivity
Expected from sequence similarity: Human
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration
100ug specific antibody in 200ul (lot specific)
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.
Antibody/Peptide Pairs
TRAF3IP1 peptide (MBS426830) is used for blocking the activity of TRAF3IP1 antibody (MBS421944)
Molecular Weight
71,529 Da
OMIM
607380
Immunogen
Peptide with sequence RCENIQPNPTEKQK, from the internal region of the protein sequence according to NP_056465.2.
Epitope
Internal region
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Applications Tested/Suitable for anti-TRAF3IP1 antibody
Peptide ELISA (EIA)
Application Notes for anti-TRAF3IP1 antibody
Peptide ELISA: Antibody detection limit dilution 1: 32000.
Western Blot: Preliminary experiments in Human Bone Marrow, Heart, Testis and Thyroid Gland lysates gave no specific signal but low background (at antibody concentration up to 1ug/ml).

Other Notes

Small volumes of anti-TRAF3IP1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for TRAF3IP1. It may not necessarily be applicable to this product.

NCBI GI #
20070262
NCBI GeneID
26146
NCBI Accession #
NP_056465.2
UniProt Secondary Accession #
Q6PCT1; Q7L8N9; Q9NRD6; Q9Y4Q1
UniProt Related Accession #
Q8TDR0
GenBank Nucleotide #
NM_015650.3
NCBI Official Full Name
TRAF3-interacting protein 1 isoform 1
NCBI Official Synonym Full Names
TRAF3 interacting protein 1
NCBI Official Symbol
TRAF3IP1
NCBI Official Synonym Symbols
IFT54; MIPT3; SLSN9; MIP-T3
UniProt Protein Name
TRAF3-interacting protein 1
UniProt Synonym Protein Names
Interleukin-13 receptor alpha 1-binding protein 1; Intraflagellar transport protein 54 homolog; Microtubule-interacting protein associated with TRAF3; MIP-T3
Protein Family
TRAF3-interacting protein
UniProt Gene Name
TRAF3IP1
UniProt Synonym Gene Names
IFT54; MIPT3; MIP-T3
UniProt Entry Name
MIPT3_HUMAN
NCBI Protein Information
TRAF3-interacting protein 1

UniProt Comments for TRAF3IP1

TRAF3IP1: Plays an inhibitory role on IL13 signaling by binding to IL13RA1. Involved in suppression of IL13-induced STAT6 phosphorylation, transcriptional activity and DNA-binding. Recruits TRAF3 and DISC1 to the microtubules. Belongs to the TRAF3IP1 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Microtubule-binding

Chromosomal Location of Human Ortholog: 2q37.3

Cellular Component: axoneme; centrosome; cytoplasm

Molecular Function: microtubule binding; protein binding

Biological Process: cilium biogenesis; embryonic camera-type eye development; embryonic digit morphogenesis; embryonic heart tube development; intraflagellar transport; kidney development; morphogenesis of a polarized epithelium; negative regulation of defense response to virus; negative regulation of interferon type I production; negative regulation of interferon-beta production; negative regulation of protein amino acid phosphorylation; negative regulation of protein complex assembly; neural tube patterning
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Research Articles on TRAF3IP1

1. Mutations in TRAF3IP1 are identified in patients with nephronophthisis and retinal degeneration. The identified mutations result in mild ciliary defects in patients and reveal a role of IFT54 as a negative regulator of microtubule stability via MAP4.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-TRAF3IP1 antibody

 Reference Product  PubMed Publications
 TRAF3 antibody  >7 publications with TRAF3IP1 and TRAF3
 DISC1 antibody  >4 publications with TRAF3IP1 and DISC1
 ATF5 antibody  >2 publications with TRAF3IP1 and ATF5
 NDEL1 antibody  >1 publications with TRAF3IP1 and NDEL1
 ATF4 antibody  >1 publications with TRAF3IP1 and ATF4

Pathways associated with anti-TRAF3IP1 antibody

 Products by Pathway  Pathway Diagram
 Assembly Of The Primary Cilium Pathway antibodies  Assembly Of The Primary Cilium Pathway Diagram
 Intraflagellar Transport Pathway antibodies  Intraflagellar Transport Pathway Diagram
 Organelle Biogenesis And Maintenance Pathway antibodies  Organelle Biogenesis And Maintenance Pathway Diagram

Diseases associated with anti-TRAF3IP1 antibody

 Disease Name  Pubmed Publications
 Necrosis Antibodies  >4 publications with TRAF3IP1 and Necrosis
 Congenital Abnormalities Antibodies  >1 publications with TRAF3IP1 and Congenital Abnormalities
 Kidney Diseases Antibodies  >1 publications with TRAF3IP1 and Kidney Diseases

Organs/Tissues associated with anti-TRAF3IP1 antibody

 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >3 publications with TRAF3IP1 and Kidney
 Nerve Antibodies  >2 publications with TRAF3IP1 and Nerve
 Eye Antibodies  >2 publications with TRAF3IP1 and Eye
 Brain Antibodies  >1 publications with TRAF3IP1 and Brain
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