NP_006450.2
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
38,926 Da
NCBI Official Full Name
erlin-1
NCBI Official Synonym Full Names
ER lipid raft associated 1
NCBI Official Synonym Symbols
KE04; KEO4; SPFH1; SPG62; Erlin-1; C10orf69 [Similar Products]
NCBI Protein Information
erlin-1
UniProt Protein Name
Erlin-1
UniProt Synonym Protein Names
Endoplasmic reticulum lipid raft-associated protein 1; Protein KE04; Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 1; SPFH domain-containing protein 1
UniProt Synonym Gene Names
C10orf69; KE04; KEO4; SPFH1; SPFH domain-containing protein 1 [Similar Products]
UniProt Entry Name
ERLN1_HUMAN
UniProt Comments for ERLIN1
SPFH1: Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs). Belongs to the band 7/mec-2 family. Forms a heteromeric complex with ERLIN2.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 10q24.31
Cellular Component: endoplasmic reticulum; endoplasmic reticulum membrane; integral to membrane; protein complex
Molecular Function: cholesterol binding; protein binding
Biological Process: cholesterol metabolic process; ER-associated protein catabolic process; negative regulation of cholesterol biosynthetic process; negative regulation of fatty acid biosynthetic process; SREBP-mediated signaling pathway
Research Articles on ERLIN1
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Diseases associated with anti-ERLIN1 antibody
Organs/Tissues associated with anti-ERLIN1 antibody
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