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X-Arrestin/Arrestin 3 (ARR3) Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS422109

MBS422109 is an antibody targeting ARR3. Also known as Goat anti-X-arrestin/arrestin 3 Antibody. Reactive in Expected from sequence similarity: Human. Host: Goat. More details

$450 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
X-arrestin/arrestin 3 (ARR3), Polyclonal Antibody
Full Product Name
Goat anti-X-arrestin/arrestin 3 Antibody
Product Gene Name
Product Synonym Names
ARR3; arrestin 3, retinal (X-arrestin); RP13-26D14. 6; ARRX; Arrestin C; ARR3 antibody; arrestin 3; retinal (X-arrestin) antibody; RP13-26D14. 6 antibody; ARRX antibody; Arrestin C antibody; X-arrestin; arrestin 3; X-arrestin / arrestin 3
Immunogen Sequence
RKGEEESQKA VE
Clonality
Polyclonal
Host
Goat
Species Reactivity
Expected from sequence similarity: Human
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration
100ug specific antibody in 200ul (lot specific)
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.
Antibody/Peptide Pairs
Molecular Weight
39,667 Da
OMIM
301770
Immunogen
Peptide with sequence C-RKGEEESQKAVE, from the C Terminus of the protein sequence according to NP_004303.2.
Epitope
C Terminus
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Applications Tested/Suitable for anti-ARR3 antibody
Peptide ELISA (EIA)
Application Notes for anti-ARR3 antibody
Peptide ELISA: Antibody detection limit dilution 1: 1000.
Western Blot: Not yet tested due to unavailability of retinal tissue. At this stage we are dependent on researchers in the field for further characterization of this product. Therefore we cannot recommend an optimal concentration and the product is an aspiring grade product.

Other Notes

Small volumes of anti-ARR3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ARR3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
arrestin-C
NCBI Official Synonym Full Names
arrestin 3 retinal (X-arrestin)
NCBI Official Symbol
ARR3
NCBI Official Synonym Symbols
ARRX; cArr
UniProt Protein Name
Arrestin-C
UniProt Synonym Protein Names
Cone arrestin; C-arrestin; cArr; Retinal cone arrestin-3; X-arrestin
Protein Family
UniProt Gene Name
ARR3
UniProt Synonym Gene Names
ARRX; CAR; C-arrestin; cArr
UniProt Entry Name
ARRC_HUMAN
NCBI Protein Information
arrestin-C

NCBI Summary for ARR3

The protein encoded by this gene is a non-visual arrestin which binds to agonist-activated, phosphorylated G protein-coupled receptors. This binding uncouples the receptor from the heterotrimeric G protein, resulting in termination of the G protein-coupled receptor signaling. The encoded protein also is a part of the centrosome, interacting with gamma-tubulin to help regulate proper centrosome function. [provided by RefSeq, May 2016]
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UniProt Comments for ARR3

ARR3: May play a role in an as yet undefined retina-specific signal transduction. Could binds to photoactivated-phosphorylated red/green opsins. Belongs to the arrestin family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: Xcen-q21

Cellular Component: cytoplasm; photoreceptor inner segment; photoreceptor outer segment; synapse

Molecular Function: opsin binding; phosphoprotein binding; protein binding; protein domain specific binding

Biological Process: endocytosis; regulation of protein amino acid phosphorylation; signal transduction; visual perception
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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