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INCA Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS422227

MBS422227 is an antibody targeting INCA. Also known as Goat anti-INCA/CARD17 Antibody. Reactive in Tested: Human; Expected from sequence similarity: Human. Host: Goat. More details

$450 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
INCA/CARD17, Polyclonal Antibody
Full Product Name
Goat anti-INCA/CARD17 Antibody
Product Gene Name
Product Synonym Gene Name
CARD17
Product Synonym Names
INCA; CARD17; caspase recruitment domain family, member 17; Inhibitory CARD; caspase recruitment domain-containing protein 17; caspase-1 inhibitor INCA; inhibitory caspase recruitment domain (CARD) protein; inhibitory caspase recruitment domain protein; INCA antibody; CARD17 antibody; caspase recruitment domain family; member 17 antibody; Inhibitory CARD antibody; caspase recruitment domain-containing protein 17 antibody; caspase-1 inhibitor INCA antibody; inhibitory caspase recruitment domain (CARD) protein antibody; inhibitory caspase recruitment domain protein antibody; INCA / CARD17
Immunogen Sequence
NHLTTQDSQI VLPS
Clonality
Polyclonal
Host
Goat
Species Reactivity
Tested: Human; Expected from sequence similarity: Human
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration
100ug specific antibody in 200ul (lot specific)
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.
Antibody/Peptide Pairs
Molecular Weight
11,868 Da
OMIM
609490
Immunogen
Peptide with sequence C-NHLTTQDSQIVLPS, from the C Terminus of the protein sequence according to NP_001007233.1.
Epitope
C Terminus
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Applications Tested/Suitable for anti-INCA antibody
Peptide ELISA (EIA), Western Blot (WB)
Application Notes for anti-INCA antibody
Peptide ELISA: Antibody detection limit dilution 1: 8000.
Western Blot: Approx 15kDa double band observed in Human Kidney and Lung lysates (calculated MW of 11.9kDa according to NP_001007233.1). Recommended concentration: 0.5-1.5ug/ml.

Western Blot (WB) of anti-INCA antibody

(0.5ug/ml) staining of Human Kidney lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Goat Anti-INCA Polyclonal Antibody – Cat# MBS422227

Other Notes

Small volumes of anti-INCA antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for INCA. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
caspase recruitment domain-containing protein 17
NCBI Official Synonym Full Names
caspase recruitment domain family member 17
NCBI Official Symbol
CARD17
NCBI Official Synonym Symbols
INCA
UniProt Protein Name
Caspase recruitment domain-containing protein 17
UniProt Synonym Protein Names
Caspase-1 inhibitor INCA; Inhibitory caspase recruitment domain protein
UniProt Gene Name
CARD17
UniProt Synonym Gene Names
INCA
UniProt Entry Name
CAR17_HUMAN
NCBI Protein Information
caspase recruitment domain-containing protein 17

UniProt Comments for INCA

CARD17: Regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-IL-1beta/IL1B and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. However, unlike CASP1, do not induce NF-kappa-B activation.

Chromosomal Location of Human Ortholog: 11q22.3

Cellular Component: cytoplasm

Molecular Function: cysteine protease inhibitor activity

Biological Process: regulation of apoptosis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
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