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UBP1 Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS422247

MBS422247 is an antibody targeting UBP1. Also known as Goat anti-UBP1 Antibody. Reactive in Expected from sequence similarity: Human, Mouse, Rat, Dog. Host: Goat. More details

$450 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
UBP1, Polyclonal Antibody
Full Product Name
Goat anti-UBP1 Antibody
Product Gene Name
anti-UBP1 antibody
Product Synonym Names
UBP1; upstream binding protein 1 (LBP-1a); DKFZp686L1745; LBP-1B; LBP-1a; LBP1A; LBP1B; transcription factor LBP-1; DKFZp686L1745 antibody; LBP1A antibody; LBP-1a antibody; LBP1B antibody; LBP-1B antibody; transcription factor LBP-1 antibody; upstream binding protein 1 (LBP-1a) antibody; UBP1 antibody
Immunogen Sequence
PNHQGDGASQ TSGE
Clonality
Polyclonal
Host
Goat
Species Reactivity
Expected from sequence similarity: Human, Mouse, Rat, Dog
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration
100ug specific antibody in 200ul (lot specific)
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.
Antibody/Peptide Pairs
UBP1 peptide (MBS426272) is used for blocking the activity of UBP1 antibody (MBS422247)
Molecular Weight
56,453 Da
OMIM
609784
Immunogen
Peptide with sequence C-PNHQGDGASQTSGE, from the internal region of the protein sequence according to NP_055332.3; NP_001121632.1.
Epitope
Internal region
Note
Reported variants represent identical protein: NP_001121633.1, NP_055332.3.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Applications Tested/Suitable for anti-UBP1 antibody
Peptide ELISA (EIA)
Application Notes for anti-UBP1 antibody
Peptide ELISA: Antibody detection limit dilution 1: 2000.
Western Blot: Preliminary experiments in Human Kidney, Human Adrenal gland, HeLa and HepG2 lysates gave no specific signal but low background (at antibody concentration up to 2ug/ml).

Other Notes

Small volumes of anti-UBP1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for UBP1. It may not necessarily be applicable to this product.

NCBI GI #
189491630
NCBI GeneID
7342
NCBI Accession #
NP_055332.3
NCBI Related Accession #
NP_001121632.1
UniProt Secondary Accession #
Q68CT0; Q86Y57; Q9H8V0; Q9UD76; Q9UD78
UniProt Related Accession #
Q9NZI7
GenBank Nucleotide #
NM_014517.4
NCBI Official Full Name
upstream-binding protein 1 isoform LBP-1b
NCBI Official Synonym Full Names
upstream binding protein 1 (LBP-1a)
NCBI Official Symbol
UBP1
NCBI Official Synonym Symbols
LBP1A; LBP1B; LBP-1B; LBP-1a
UniProt Protein Name
Upstream-binding protein 1
UniProt Synonym Protein Names
Transcription factor LBP-1
Protein Family
Oligouridylate-binding protein
UniProt Gene Name
UBP1
UniProt Synonym Gene Names
LBP1
UniProt Entry Name
UBIP1_HUMAN
NCBI Protein Information
upstream-binding protein 1

UniProt Comments for UBP1

UBP1: Functions as a transcriptional activator in a promoter context-dependent manner. Modulates the placental expression of CYP11A1. Involved in regulation of the alpha-globin gene in erythroid cells. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with TFCP2. Involved in regulation of the alpha-globin gene in erythroid cells. Binds strongly to sequences around the HIV-1 initiation site and weakly over the TATA-box. Represses HIV-1 transcription by inhibiting the binding of TFIID to the TATA-box. Belongs to the grh/CP2 family. CP2 subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 3p22.3

Cellular Component: cytoplasm; nucleoplasm; nucleus

Molecular Function: DNA binding; sequence-specific DNA binding; transcription corepressor activity; transcription factor activity

Biological Process: angiogenesis; negative regulation of transcription, DNA-dependent; regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent; viral genome replication
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Research Articles on UBP1

1. Data revealed that dimers composed of LBP-1a and LBP-1c were re-formed probably by a partner-exchange of LBP-1b-containing heterodimers.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-UBP1 antibody

 Reference Product  PubMed Publications
 TFCP2L1 antibody  >4 publications with UBP1 and TFCP2L1
 YY1 antibody  >2 publications with UBP1 and YY1
 CYP11A1 antibody  >2 publications with UBP1 and CYP11A1

Diseases associated with anti-UBP1 antibody

 Disease Name  Pubmed Publications
 Immune System Diseases Antibodies  >1 publications with UBP1 and Immune System Diseases
 Vascular Diseases Antibodies  >1 publications with UBP1 and Vascular Diseases
 Urogenital Abnormalities Antibodies  >1 publications with UBP1 and Urogenital Abnormalities
 Embryo Loss Antibodies  >1 publications with UBP1 and Embryo Loss
 Fetal Death Antibodies  >1 publications with UBP1 and Fetal Death
 Inflammation Antibodies  >1 publications with UBP1 and Inflammation
 Necrosis Antibodies  >1 publications with UBP1 and Necrosis

Organs/Tissues associated with anti-UBP1 antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >4 publications with UBP1 and Blood
 Placenta Antibodies  >4 publications with UBP1 and Placenta
 Embryonic Tissue Antibodies  >3 publications with UBP1 and Embryonic Tissue
 Bone Marrow Antibodies  >2 publications with UBP1 and Bone Marrow
 Lung Antibodies  >2 publications with UBP1 and Lung
 Bone Antibodies  >2 publications with UBP1 and Bone
 Connective Tissue Antibodies  >1 publications with UBP1 and Connective Tissue
 Liver Antibodies  >1 publications with UBP1 and Liver
 Skin Antibodies  >1 publications with UBP1 and Skin
 Kidney Antibodies  >1 publications with UBP1 and Kidney
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