MEIS2 Antibody – Goat Polyclonal

This gene encodes a homeobox protein belonging to the TALE ('three amino acid loop extension') family of homeodomain-containing proteins. TALE homeobox proteins are highly conserved transcription regulators, and several members have been shown to be essential contributors to developmental programs. Multiple transcript variants encoding distinct isoforms have been described for this gene. [provided by RefSeq, Jul 2008]

MEIS2: a homeobox protein belonging to the TALE ('three amino acid loop extension') family of homeodomain-containing proteins. TALE homeobox proteins are highly conserved transcription regulators, and several members have been shown to be essential contributors to developmental programs. Multiple transcript variants encoding distinct isoforms have been described for this gene. [provided by RefSeq, Jul 2008]

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 15q14

Cellular Component: nucleus; perinuclear region of cytoplasm

Molecular Function: protein binding; sequence-specific DNA binding; transcription cofactor activity; transcription corepressor activity; transcription factor activity; transcription factor binding

Biological Process: eye development; negative regulation of myeloid cell differentiation; negative regulation of transcription from RNA polymerase II promoter; pancreas development; positive regulation of transcription from RNA polymerase II promoter; response to mechanical stimulus; transcription from RNA polymerase II promoter; visual learning