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SIGLEC6 Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS422434

MBS422434 is an antibody targeting SIGLEC6. Also known as Goat anti-SIGLEC6 Antibody. Reactive in Tested: Human; Expected from sequence similarity: Human. Host: Goat. More details

$450 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SIGLEC6, Polyclonal Antibody
Full Product Name
Goat anti-SIGLEC6 Antibody
Product Gene Name
Product Synonym Names
SIGLEC6; sialic acid binding Ig-like lectin 6; CD327; CD33L; CD33L1; CDw327; OBBP1; SIGLEC-6; CD33 antigen-like 1; CDw327 antigen; Obesity-binding protein 1; CD327 antibody; CD33 antigen-like 1 antibody; CD33L antibody; CD33L1 antibody; CDw327 antibody; CDw327 antigen antibody; OBBP1 antibody; Obesity-binding protein 1 antibody; sialic acid binding Ig-like lectin 6 antibody; SIGLEC-6 antibody; SIGLEC6 antibody
Immunogen Sequence
KWMKYGYTSS K
Clonality
Polyclonal
Host
Goat
Species Reactivity
Tested: Human; Expected from sequence similarity: Human
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration
100ug specific antibody in 200ul (lot specific)
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.
Antibody/Peptide Pairs
SIGLEC6 peptide (MBS427381) is used for blocking the activity of SIGLEC6 antibody (MBS422434)
Molecular Weight
44,348 Da
OMIM
604405
Immunogen
Peptide with sequence C-KWMKYGYTSSK, from the internal region of the protein sequence according to NP_001236.4; NP_942142.3; NP_942143.3.
Epitope
Internal region
Note
This antibody is expected to recognize all reported isoforms (NP_001236.4; NP_942142.3; NP_942143.3).
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Applications Tested/Suitable for anti-SIGLEC6 antibody
Peptide ELISA (EIA), Western Blot (WB)
Application Notes for anti-SIGLEC6 antibody
Peptide ELISA: Antibody detection limit dilution 1: 16000.
Western Blot: Experiments gave bands at approx 60kDa and 35kDa in Human Placenta lysates. These bands correspond to earlier findings with different antibodies from other commercial sources. This protein has a calculated MW of 49.9kDa according to NP_001236.4. Recommended concentration: 0.5-1.5ug/ml.

Western Blot (WB) of anti-SIGLEC6 antibody

(0.5ug/ml) staining of Human Placenta lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Goat Anti-SIGLEC6 Polyclonal Antibody – Cat# MBS422434

Other Notes

Small volumes of anti-SIGLEC6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for SIGLEC6. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI Related Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
sialic acid-binding Ig-like lectin 6 isoform 1
NCBI Official Synonym Full Names
sialic acid binding Ig like lectin 6
NCBI Official Symbol
SIGLEC6
NCBI Official Synonym Symbols
CD327; CD33L; OBBP1; CD33L1; CD33L2; CDW327
UniProt Protein Name
Sialic acid-binding Ig-like lectin 6
UniProt Synonym Protein Names
CD33 antigen-like 1; CDw327; Obesity-binding protein 1; OB-BP1; CD_antigen: CD327
UniProt Gene Name
SIGLEC6
UniProt Synonym Gene Names
CD33L; CD33L1; OBBP1; Siglec-6; OB-BP1
UniProt Entry Name
SIGL6_HUMAN
NCBI Protein Information
sialic acid-binding Ig-like lectin 6

UniProt Comments for SIGLEC6

SIGLEC6: Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. Belongs to the immunoglobulin superfamily. SIGLEC (sialic acid binding Ig-like lectin) family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Receptor, misc.; Membrane protein, integral

Chromosomal Location of Human Ortholog: 19q13.3

Cellular Component: extracellular region; integral to plasma membrane; membrane

Molecular Function: carbohydrate binding; protein binding

Biological Process: cell adhesion; cell-cell signaling
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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