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MOGAT2 Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS422451

MBS422451 is an antibody targeting MOGAT2. Also known as Goat anti-MOGAT2 Antibody. Reactive in Tested: Human; Expected from sequence similarity: Human, Dog, Cow, Pig. Host: Goat. More details

$450 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
MOGAT2, Polyclonal Antibody
Full Product Name
Goat anti-MOGAT2 Antibody
Product Gene Name
anti-MOGAT2 antibody
Product Synonym Names
MOGAT2; monoacylglycerol O-acyltransferase 2; DGAT2L5; FLJ22644; MGAT2; MGC119183; MGC119184; MGC119185; acyl CoA: monoacylglycerol acyltransferase 2; acyl CoA: monoacylglycerol acyltransferase 2 antibody; DGAT2L5 antibody; FLJ22644 antibody; MGAT2 antibody; MGC119183 antibody; MGC119184 antibody; MGC119185 antibody; monoacylglycerol O-acyltransferase 2 antibody; MOGAT2 antibody
Immunogen Sequence
KESAAHILNR K
Clonality
Polyclonal
Host
Goat
Species Reactivity
Tested: Human; Expected from sequence similarity: Human, Dog, Cow, Pig
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration
100ug specific antibody in 200ul (lot specific)
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.
Antibody/Peptide Pairs
MOGAT2 peptide (MBS427330) is used for blocking the activity of MOGAT2 antibody (MBS422451)
Molecular Weight
32,298 Da
OMIM
610270
Immunogen
Peptide with sequence C-KESAAHILNRK, from the internal region of the protein sequence according to NP_079374.2.
Epitope
Internal region
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Applications Tested/Suitable for anti-MOGAT2 antibody
Peptide ELISA (EIA), Western Blot (WB)
Application Notes for anti-MOGAT2 antibody
Peptide ELISA: Antibody detection limit dilution 1: 32000.
Western Blot: Approx 37kDa band observed in Human Colon, Duodenum and Ileum lysates (calculated MW of 38.2kDa according to NP_079374.2). Recommended concentration: 0. 05-0.2ug/ml.

Western Blot (WB) of anti-MOGAT2 antibody

(0. 05ug/ml) staining of Human Duodenum lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Goat Anti-MOGAT2 Polyclonal Antibody – Cat# MBS422451

Other Notes

Small volumes of anti-MOGAT2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for MOGAT2. It may not necessarily be applicable to this product.

NCBI GI #
37537527
NCBI GeneID
80168
NCBI Accession #
NP_079374.2
UniProt Secondary Accession #
Q3SYC1; Q6ZQZ2; Q86UH6; Q9H630; A8K7I3
UniProt Related Accession #
Q3SYC2
GenBank Nucleotide #
NM_025098.3
NCBI Official Full Name
2-acylglycerol O-acyltransferase 2
NCBI Official Synonym Full Names
monoacylglycerol O-acyltransferase 2
NCBI Official Symbol
MOGAT2
NCBI Official Synonym Symbols
hDC5; MGAT2; DGAT2L5; DGAT2L5.
UniProt Protein Name
2-acylglycerol O-acyltransferase 2
UniProt Synonym Protein Names
Acyl-CoA:monoacylglycerol acyltransferase 2; MGAT2; hMGAT2; Diacylglycerol O-acyltransferase candidate 5; hDC5; Diacylglycerol acyltransferase 2-like protein 5; Monoacylglycerol O-acyltransferase 2
Protein Family
2-acylglycerol O-acyltransferase
UniProt Gene Name
MOGAT2
UniProt Synonym Gene Names
DC5; DGAT2L5; MGAT2; hMGAT2; hDC5
UniProt Entry Name
MOGT2_HUMAN
NCBI Protein Information
2-acylglycerol O-acyltransferase 2

NCBI Summary for MOGAT2

The protein encoded by this gene is an enzyme that catalyzes the synthesis of diacylglycerol from 2-monoacylglycerol and fatty acyl-CoA. The encoded protein is important in the uptake of dietary fat by the small intestine. This protein forms a complex with diacylglycerol O-acyltransferase 2 in the endoplasmic reticulum, and this complex catalyzes the synthesis of triacylglycerol. [provided by RefSeq, Dec 2015]
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UniProt Comments for MOGAT2

MOGAT2: Catalyzes the formation of diacylglycerol from 2- monoacylglycerol and fatty acyl-CoA. Has a preference toward monoacylglycerols containing unsaturated fatty acids in an order of C18:3 > C18:2 > C18:1 > C18:0. Plays a central role in absorption of dietary fat in the small intestine by catalyzing the resynthesis of triacylglycerol in enterocytes. May play a role in diet-induced obesity. Belongs to the diacylglycerol acyltransferase family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; EC 2.3.1.22; Acetyltransferase; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 11q13.5

Cellular Component: endoplasmic reticulum; endoplasmic reticulum membrane; integral to membrane

Molecular Function: 2-acylglycerol O-acyltransferase activity; acetyltransferase activity

Biological Process: diacylglycerol biosynthetic process; glycerol metabolic process; intestinal absorption; triacylglycerol biosynthetic process
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Research Articles on MOGAT2

1. MGAT2 in the intestine plays an indispensable role in enhancing metabolic efficiency but also raise the possibility that MGAT2 in other tissues may contribute to the regulation of energy metabolism.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-MOGAT2 antibody

 Products by Pathway  Pathway Diagram
 Fat Digestion And Absorption Pathway antibodies  Fat Digestion And Absorption Pathway Diagram
 Fat Digestion And Absorption Pathway antibodies  Fat Digestion And Absorption Pathway Diagram
 Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway antibodies  Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway Diagram
 Glycerolipid Metabolism Pathway antibodies  Glycerolipid Metabolism Pathway Diagram
 Glycerolipid Metabolism Pathway antibodies  Glycerolipid Metabolism Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Lipids And Lipoproteins Pathway antibodies  Metabolism Of Lipids And Lipoproteins Pathway Diagram
 Triacylglyceride Synthesis Pathway antibodies  Triacylglyceride Synthesis Pathway Diagram
 Triglyceride Biosynthesis Pathway antibodies  Triglyceride Biosynthesis Pathway Diagram

Diseases associated with anti-MOGAT2 antibody

 Disease Name  Pubmed Publications
 Weight Gain Antibodies  >4 publications with MOGAT2 and Weight Gain
 Liver Diseases Antibodies  >2 publications with MOGAT2 and Liver Diseases
 Fatty Liver Antibodies  >2 publications with MOGAT2 and Fatty Liver
 Weight Loss Antibodies  >2 publications with MOGAT2 and Weight Loss
 Fatty Liver, Alcoholic Antibodies  >1 publications with MOGAT2 and Fatty Liver, Alcoholic
 Non-alcoholic Fatty Liver Disease Antibodies  >1 publications with MOGAT2 and Non-alcoholic Fatty Liver Disease
 Cardiovascular Diseases Antibodies  >1 publications with MOGAT2 and Cardiovascular Diseases
 Breast Neoplasms Antibodies  >1 publications with MOGAT2 and Breast Neoplasms

Organs/Tissues associated with anti-MOGAT2 antibody

 Organ/Tissue Name  Pubmed Publications
 Intestine Antibodies  >3 publications with MOGAT2 and Intestine
 Liver Antibodies  >2 publications with MOGAT2 and Liver
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