Goat Anti-LGALS3 Polyclonal Antibody – Cat# MBS422541

(0.5ug/ml) staining of Mouse Heart lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Galectin-3 (LGALS3) Antibody – Goat Polyclonal

Name: LGALS3 Antibody; Polyclonal; Goat; Mouse-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS422541
Price: 450 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS422541

MBS422541 is an antibody targeting Lgals3. Also known as Goat anti-galectin-3 (mouse) Antibody. Reactive in Tested: Mouse; Expected from sequence similarity: Mouse. Host: Goat. More details

$450 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

galectin-3 (Lgals3), Polyclonal Antibody

Full Product Name

Goat anti-galectin-3 (mouse) Antibody

Product Gene Name

anti-Lgals3 antibody

Product Synonym Names

Lgals3; lectin, galactose binding, soluble 3; GBP; L-34; Mac-2; gal3; 35 kDa lectin; CBP 35; L-34 galactoside-binding lectin; OTTMUSP00000043688; OTTMUSP00000043689; OTTMUSP00000043690; carbohydrate-binding protein 35; gal-3; galactose-specific lectin 3; Lgals3 antibody; lectin; galactose binding; soluble 3 antibody; GBP antibody; L-34 antibody; Mac-2 antibody; gal3 antibody; 35 kDa lectin antibody; CBP 35 antibody; L-34 galactoside-binding lectin antibody; OTTMUSP00000043689 antibody; OTTMUSP00000043690 antibody; carbohydrate-binding protein 35 antibody; gal-3 antibody; galactose-specific lectin 3 antibody; Galectin-3; galectin-3 (mouse)

Immunogen Sequence

NANRIVLDFR RGND

Clonality

Polyclonal

Host

Goat

Species Reactivity

Tested: Mouse; Expected from sequence similarity: Mouse

Form/Format

Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Purity/Purification

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Concentration

100ug specific antibody in 200ul (lot specific)

Preparation and Storage

Aliquot and store at -20 degree C. Minimize freezing and thawing.

Antibody/Peptide Pairs

galectin-3 peptide (MBS427592) is used for blocking the activity of galectin-3 antibody (MBS422541)

Molecular Weight

27,515 Da

Immunogen

Peptide with sequence C-NANRIVLDFRRGND, from the internal region of the protein sequence according to NP_034835.1.

Epitope

Internal region

Note

Reported variants represent identical protein: NP_001139425.1, NP_034835.1

ISO Certification

Manufactured in an ISO 9001:2008 Certified Laboratory.

Applications Tested/Suitable for anti-Lgals3 antibody

Peptide ELISA (EIA), Western Blot (WB)

Application Notes for anti-Lgals3 antibody

Peptide ELISA: Antibody detection limit dilution 1: 4000.
Western Blot: Approx 26kDa band observed in Mouse Heart lysates (calculated MW of 27.4kDa according to NP_034835.1). Recommended concentration: 0.5-2ug/ml.

Other Notes

Small volumes of anti-Lgals3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Lgals3. It may not necessarily be applicable to this product.

NCBI GI #

33859580

NCBI GeneID

16854

NCBI Accession #

NP_034835.1

UniProt Related Accession #

P16110

GenBank Nucleotide #

NM_010705.3

NCBI Official Full Name

galectin-3

NCBI Official Synonym Full Names

lectin, galactose binding, soluble 3

NCBI Official Symbol

Lgals3

NCBI Official Synonym Symbols

GBP; L-34; gal3; Mac-2

UniProt Protein Name

Galectin-3

UniProt Synonym Protein Names

35 kDa lectin; Carbohydrate-binding protein 35; CBP 35; Galactose-specific lectin 3; IgE-binding protein; L-34 galactoside-binding lectin; Laminin-binding protein; Lectin L-29; Mac-2 antigen

Protein Family

Galectin-3-binding protein

UniProt Gene Name

Lgals3

UniProt Synonym Gene Names

Gal-3; CBP 35

UniProt Entry Name

LEG3_MOUSE

NCBI Protein Information

galectin-3

UniProt Comments for Lgals3

galectin-3: galactose-specific lectin which binds IgE. Expressed at a high level in the colonic epithelium. Also abundant in activated macrophages.

Protein type: Motility/polarity/chemotaxis; Cell surface; Extracellular matrix

Cellular Component: cell surface; cytoplasm; external side of plasma membrane; extracellular matrix; extracellular region; extracellular space; immunological synapse; membrane; mitochondrial inner membrane; nucleus; proteinaceous extracellular matrix; spliceosome

Molecular Function: advanced glycation end-product receptor activity; carbohydrate binding; chemoattractant activity; disaccharide binding; IgE binding; laminin binding; monosaccharide binding; protein binding

Biological Process: cell differentiation; eosinophil chemotaxis; extracellular matrix organization and biogenesis; immune system process; innate immune response; macrophage chemotaxis; maintenance of protein localization; monocyte chemotaxis; mRNA processing; negative regulation of apoptosis; negative regulation of endocytosis; negative regulation of T cell receptor signaling pathway; neutrophil chemotaxis; positive chemotaxis; positive regulation of angiogenesis; positive regulation of cell proliferation; positive regulation of serotonin secretion; regulation of T cell proliferation; RNA splicing; signal transduction; skeletal development

Research Articles on Lgals3

1. B-cell precursor acute lymphoblastic leukemia and stromal cells communicate through galectin-3 signaling.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-Lgals3 antibody

Reference Product	PubMed Publications
Tnf antibody	>61 publications with Lgals3 and Tnf
Lgals3bp antibody	>51 publications with Lgals3 and Lgals3bp
Kras antibody	>10 publications with Lgals3 and Kras
Dmbt1 antibody	>8 publications with Lgals3 and Dmbt1
Ptprc antibody	>2 publications with Lgals3 and Ptprc
Ddost antibody	>2 publications with Lgals3 and Ddost
Prkcsh antibody	>2 publications with Lgals3 and Prkcsh
Sufu antibody	>1 publications with Lgals3 and Sufu

Organs/Tissues associated with anti-Lgals3 antibody

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>742 publications with Lgals3 and Blood
Thyroid Antibodies	>324 publications with Lgals3 and Thyroid
Brain Antibodies	>193 publications with Lgals3 and Brain
Liver Antibodies	>149 publications with Lgals3 and Liver
Kidney Antibodies	>147 publications with Lgals3 and Kidney
Lung Antibodies	>145 publications with Lgals3 and Lung
Muscle Antibodies	>125 publications with Lgals3 and Muscle
Bone Antibodies	>124 publications with Lgals3 and Bone
Skin Antibodies	>98 publications with Lgals3 and Skin
Bone Marrow Antibodies	>73 publications with Lgals3 and Bone Marrow