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ITIH4 Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS422650

MBS422650 is an antibody targeting ITIH4. Also known as Goat anti-ITIH4 (aa890-903) Antibody. Reactive in Tested: Human; Expected from sequence similarity: Human. Host: Goat. More details

$450 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ITIH4, Polyclonal Antibody
Full Product Name
Goat anti-ITIH4 (aa890-903) Antibody
Product Gene Name
Product Synonym Names
Goat Anti-ITIH4 Antibody; ITIH4; inter-alpha (globulin) inhibitor H4 (plasma Kallikrein-sensitive glycoprotein); DKFZp686G21125; H4P; IHRP; ITIHL1; PK120; ITI heavy chain H4; ITI-HC4; OTTHUMP00000197121; OTTHUMP00000213834; OTTHUMP00000213869; PK-120; gp120; inter-alpha-inhibitor; ITIH4 antibody; inter-alpha (globulin) inhibitor H4 (plasma Kallikrein-sensitive glycoprotein) antibody; DKFZp686G21125 antibody; H4P antibody; IHRP antibody; ITIHL1 antibody; PK120 antibody; ITI heavy chain H4 antibody; ITI-HC4 antibody; OTTHUMP00000213834 antibody; OTTHUMP00000213869 antibody; PK-120 antibody; gp120 antibody; inter-alpha-inhibitor antibody; ITIH4 (aa890-903)
Immunogen Sequence
SDDGRRTLRV QGND
Clonality
Polyclonal
Host
Goat
Species Reactivity
Tested: Human; Expected from sequence similarity: Human
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration
100ug specific antibody in 200ul (lot specific)
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.
Antibody/Peptide Pairs
ITIH4 peptide (MBS427552) is used for blocking the activity of ITIH4 antibody (MBS422650)
Molecular Weight
93,852 Da
OMIM
600564
Immunogen
Peptide with sequence C-SDDGRRTLRVQGND, from the C Terminus of the protein sequence according to NP_002209.2; NP_001159921.1.
Epitope
C Terminus
Note
This antibody is expected to recognize both reported isoforms (NP_002209.2; NP_001159921.1).
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Applications Tested/Suitable for anti-ITIH4 antibody
Peptide ELISA (EIA), Western Blot (WB)
Application Notes for anti-ITIH4 antibody
Peptide ELISA: Antibody detection limit dilution 1: 16000.
Western Blot: Approx 150kDa band observed in Human Placenta lysates (calculated MW of 103kDa according to NP_002209.2). The observed molecular weight corresponds to the glycosylated form. Recommended concentration: 0. 03-0.1ug/ml.

Western Blot (WB) of anti-ITIH4 antibody

(0. 03ug/ml) staining of Human Placenta lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Goat Anti-ITIH4 Polyclonal Antibody – Cat# MBS422650

Other Notes

Small volumes of anti-ITIH4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ITIH4. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI Related Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
inter-alpha-trypsin inhibitor heavy chain H4 isoform 1
NCBI Official Synonym Full Names
inter-alpha-trypsin inhibitor heavy chain family member 4
NCBI Official Symbol
ITIH4
NCBI Official Synonym Symbols
H4P; IHRP; GP120; PK120; ITIHL1; PK-120; ITI-HC4
UniProt Protein Name
Inter-alpha-trypsin inhibitor heavy chain H4
UniProt Synonym Protein Names
Inter-alpha-trypsin inhibitor family heavy chain-related protein; IHRP
UniProt Gene Name
ITIH4
UniProt Synonym Gene Names
IHRP; ITIHL1; PK120; ITI heavy chain H4; ITI-HC4; Inter-alpha-inhibitor heavy chain 4; IHRP; Gp120; PK-120
UniProt Entry Name
ITIH4_HUMAN
NCBI Protein Information
inter-alpha-trypsin inhibitor heavy chain H4

NCBI Summary for ITIH4

The protein encoded by this gene is secreted into the blood, where it is cleaved by plasma kallikrein into two smaller forms. Expression of this gene has been detected only in liver, and it seems to be upregulated during surgical trauma. This gene is part of a cluster of similar genes on chromosome 3. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
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UniProt Comments for ITIH4

ITIH4: May be involved in acute phase reactions. Belongs to the ITIH family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 3p21.1

Cellular Component: extracellular region; plasma membrane

Molecular Function: endopeptidase inhibitor activity; protein binding; serine-type endopeptidase inhibitor activity

Biological Process: acute-phase response; hyaluronan metabolic process; platelet degranulation; response to cytokine stimulus

Disease: Hypercholesterolemia, Familial
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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