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Orexin Receptor 2 (HCRTR2) Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS422717

MBS422717 is an antibody targeting HCRTR2. Also known as Goat anti-Orexin Receptor 2 (aa405-419) Antibody. Reactive in Tested: Mouse; Expected from sequence similarity: Human, Mouse, Rat, Dog, Pig, Cow. Host: Goat. More details

$450 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
Orexin Receptor 2 (HCRTR2), Polyclonal Antibody
Full Product Name
Goat anti-Orexin Receptor 2 (aa405-419) Antibody
Product Gene Name
Product Synonym Names
Goat Anti-Orexin Receptor 2 Antibody; HCRTR2; hypocretin (orexin) receptor 2; OX2R; hypocretin receptor type 2; orexin receptor type 2; ox-2-R; ox2-R; HCRTR2 antibody; hypocretin (orexin) receptor 2 antibody; OX2R antibody; hypocretin receptor type 2 antibody; orexin receptor type 2 antibody; ox-2-R antibody; ox2-R antibody; Orexin Receptor 2; Orexin Receptor 2 (aa405-419)
Immunogen Sequence
KSLTTQISNF DNISK
Clonality
Polyclonal
Host
Goat
Species Reactivity
Tested: Mouse; Expected from sequence similarity: Human, Mouse, Rat, Dog, Pig, Cow
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration
100ug specific antibody in 200ul (lot specific)
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.
Antibody/Peptide Pairs
OMIM
602393
Immunogen
Peptide with sequence C-KSLTTQISNFDNISK, from the internal region (near C Terminus) of the protein sequence according to NP_001517.2.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Applications Tested/Suitable for anti-HCRTR2 antibody
Peptide ELISA (EIA), Western Blot (WB)
Application Notes for anti-HCRTR2 antibody
Peptide ELISA: Antibody detection limit dilution 1: 32000.
Western Blot: Approx 50kDa band observed in Mouse fetal Brain lysates (calculated MW of 52.5kDa according to Mouse NP_945200.1). Recommended concentration: 0.5-2ug/ml.
Primary Incubation was 1 hour

Western Blot (WB) of anti-HCRTR2 antibody

(0.5ug/ml) staining of Mouse fetal Brain lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Goat Anti-HCRTR2 Polyclonal Antibody – Cat# MBS422717

Other Notes

Small volumes of anti-HCRTR2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for HCRTR2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
orexin receptor type 2
NCBI Official Synonym Full Names
hypocretin receptor 2
NCBI Official Symbol
HCRTR2
NCBI Official Synonym Symbols
OX2R
UniProt Protein Name
Orexin receptor type 2
UniProt Synonym Protein Names
Hypocretin receptor type 2
Protein Family
UniProt Gene Name
HCRTR2
UniProt Synonym Gene Names
Ox-2-R; Ox2-R; Ox2R
UniProt Entry Name
OX2R_HUMAN
NCBI Protein Information
orexin receptor type 2

NCBI Summary for HCRTR2

The protein encoded by this gene is a G-protein coupled receptor involved in the regulation of feeding behavior. The encoded protein binds the hypothalamic neuropeptides orexin A and orexin B. A related gene (HCRTR1) encodes a G-protein coupled receptor that selectively binds orexin A. [provided by RefSeq, Jan 2009]
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UniProt Comments for HCRTR2

HCRTR2: Nonselective, high-affinity receptor for both orexin-A and orexin-B neuropeptides. Belongs to the G-protein coupled receptor 1 family.

Protein type: Membrane protein, multi-pass; Receptor, GPCR; GPCR, family 1; Membrane protein, integral

Chromosomal Location of Human Ortholog: 6p12

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: neuropeptide receptor activity; orexin receptor activity; peptide binding; peptide hormone binding

Biological Process: cellular response to hormone stimulus; circadian sleep/wake cycle process; feeding behavior; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); neuropeptide signaling pathway; regulation of circadian sleep/wake cycle, sleep; synaptic transmission
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-HCRTR2 antibody

Organs/Tissues associated with anti-HCRTR2 antibody

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