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PPRC1 Antibody – Rabbit

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS004229

MBS004229 is an antibody targeting PPRC1. Also known as Rabbit PPRC1 Antibody. Reactive in Human, mouse. Host: Rabbit. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
PPRC1, Antibody
Full Product Name
Rabbit PPRC1 Antibody
Product Gene Name
Host
Rabbit
Species Reactivity
Human, mouse
Form/Format
Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
Concentration
1 mg/ml (lot specific)
Molecular Weight
177,544 Da
Chromosome Location
Chromosome: 10; NC_000010.10 (103892787..103910090). Location: 10q24.32
3D Structure
ModBase 3D Structure for Q5VV67
Applications Tested/Suitable for anti-PPRC1 antibody
Immunohistochemistry (IHC), ELISA (EIA)

Other Notes

Small volumes of anti-PPRC1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PPRC1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
peroxisome proliferator-activated receptor gamma coactivator-related protein 1
NCBI Official Synonym Full Names
peroxisome proliferator-activated receptor gamma, coactivator-related 1
NCBI Official Symbol
PPRC1
NCBI Official Synonym Symbols
PRC; RP11-302K17.6
UniProt Protein Name
Peroxisome proliferator-activated receptor gamma coactivator-related protein 1
UniProt Synonym Protein Names
PGC-1-related coactivator
UniProt Gene Name
PPRC1
UniProt Synonym Gene Names
KIAA0595; PRC
UniProt Entry Name
PPRC1_HUMAN
NCBI Protein Information
peroxisome proliferator-activated receptor gamma coactivator-related protein 1; PGC-1-related coactivator; PGC-1 related co-activator; peroxisome proliferative activated receptor, gamma, coactivator-related 1

NCBI Summary for PPRC1

The protein encoded by this gene is similar to PPAR-gamma coactivator 1 (PPARGC1/PGC-1), a protein that can activate mitochondrial biogenesis in part through a direct interaction with nuclear respiratory factor 1 (NRF1). This protein has been shown to interact with NRF1. It is thought to be a functional relative of PPARGC1 that activates mitochondrial biogenesis through NRF1 in response to proliferative signals. [provided by RefSeq, Jul 2008]
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UniProt Comments for PPRC1

PPRC1: Acts as a coactivator during transcriptional activation of nuclear genes related to mitochondrial biogenesis and cell growth. Involved in the transcription coactivation of CREB and NRF1 target genes. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Transcription, coactivator/corepressor

Chromosomal Location of Human Ortholog: 10q24.32

Cellular Component: nucleoplasm

Molecular Function: ligand-dependent nuclear receptor transcription coactivator activity; nucleotide binding; transcription factor binding

Biological Process: transcription from RNA polymerase II promoter; mitochondrion organization and biogenesis; organelle organization and biogenesis; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription factor activity
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-PPRC1 antibody

 Reference Product  PubMed Publications
 NRF1 antibody  >1 publications with PPRC1 and NRF1

Pathways associated with anti-PPRC1 antibody

 Products by Pathway  Pathway Diagram
 Energy Metabolism Pathway antibodies  Energy Metabolism Pathway Diagram
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