Goat Anti-HWP1 Polyclonal Antibody – Cat# MBS422902

HWP1 Antibody – Goat Polyclonal

Name: HWP1 Antibody; Polyclonal; Goat; Candida-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS422902
Price: 305 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS422902

MBS422902 is an antibody targeting HWP1. Also known as Goat anti-HWP1 (Candida) Antibody. Reactive in Expected from sequence similarity: Candida albicans SC5314. Host: Goat. More details

$305 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

HWP1, Polyclonal Antibody

Full Product Name

Goat anti-HWP1 (Candida) Antibody

Product Gene Name

anti-HWP1 antibody

Product Synonym Names

HWP1; ECE2; ECE2 antibody; HWP1 antibody; HWP1 (Candida)

Immunogen Sequence

QPSIPAGETS PAVPK

Clonality

Polyclonal

Host

Goat

Species Reactivity

Expected from sequence similarity: Candida albicans SC5314

Form/Format

Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Purity/Purification

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Concentration

100ug specific antibody in 200ul (lot specific)

Preparation and Storage

Aliquot and store at -20 degree C. Minimize freezing and thawing.

Antibody/Peptide Pairs

HWP1 peptide (MBS427805) is used for blocking the activity of HWP1 antibody (MBS422902)

Immunogen

Peptide with sequence C-QPSIPAGETSPAVPK, from the internal region of the protein sequence according to XP_712998.1.

Epitope

Internal region

ISO Certification

Manufactured in an ISO 9001:2008 Certified Laboratory.

Applications Tested/Suitable for anti-HWP1 antibody

Peptide ELISA (EIA)

Application Notes for anti-HWP1 antibody

Peptide ELISA: Antibody detection limit dilution 1: 128000.
Western Blot: Not yet tested. At this stage we are dependent on researchers in the field for further characterization of this product. Therefore we cannot recommend an optimal concentration and the antibody is an aspiring product.

Other Notes

Small volumes of anti-HWP1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for HWP1. It may not necessarily be applicable to this product.

NCBI GI #

68486282

NCBI GeneID

3645386

NCBI Accession #

XP_712998.1

UniProt Secondary Accession #

O13424; P87019; Q59TL7

UniProt Related Accession #

P46593

GenBank Nucleotide #

XM_707905.1

NCBI Official Full Name

hyphal-specific cell wall protein aka ECE2

NCBI Official Symbol

HWP1

UniProt Protein Name

Hyphal wall protein 1

UniProt Synonym Protein Names

Cell elongation protein 2

Protein Family

Hyphal wall protein

UniProt Gene Name

HWP1

UniProt Synonym Gene Names

ECE2

UniProt Entry Name

HWP1_CANAL

NCBI Protein Information

hyphal-specific cell wall protein; aka ECE2; C terminus similar to that of HWP99 and RBT1; similar to S. cerevisiae MUC1 (YIR019C) cell surface flocculin

UniProt Comments for HWP1

Major hyphal cell wall protein which plays a role of adhesin and is required for mating, normal hyphal development, cell-to-cell adhesive functions necessary for biofilm integrity, attachment to host, and virulence. Promotes interactions with host and bacterial molecules, thus leading to effective colonization within polymicrobial communities. Plays a crucial role in gastrointestinal colonization, in mucosal symptomatic and asymptomatic infections, in vaginitis, as well as in lethal oroesophageal candidiasis, caused by the combined action of fungal virulence factors and host inflammatory responses when protective immunity is absent.

Research Articles on HWP1

1. Hwp1 appears to have a minor role in disseminated candidiasis, independent of host tissue transglutaminase, but has a key function in host- and self-association to the surface of oral mucosa.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.