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MRG/MORF4L (MRGBP) Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS422905

MBS422905 is an antibody targeting MRGBP. Also known as Goat anti-MRG/MORF4L binding protein Antibody. Reactive in Tested: Human; Expected from sequence similarity: Human, Mouse, Rat, Cow. Host: Goat. More details

$450 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
MRG/MORF4L (MRGBP), Polyclonal Antibody
Full Product Name
Goat anti-MRG/MORF4L binding protein Antibody
Product Gene Name
anti-MRGBP antibody
Product Synonym Gene Name
MRG; MORF4L
Product Synonym Names
C20orf20; chromosome 20 open reading frame 20; Eaf7; FLJ10914; MRG15BP; MRGBP; URCC4; MRG(MORF4-related gene)-binding protein; MRG-binding protein; OTTHUMP00000031512; C20orf20 antibody; chromosome 20 open reading frame 20 antibody; Eaf7 antibody; FLJ10914 antibody; MRG(MORF4-related gene)-binding protein antibody; MRG15BP antibody; MRG-binding protein antibody; MRGBP antibody; OTTHUMP00000031512 antibody; URCC4 antibody; MRG/MORF4L binding protein antibody; MRG/MORF4L binding protein
Immunogen Sequence
CIRDKFSQNI GRQVP
Clonality
Polyclonal
Host
Goat
Species Reactivity
Tested: Human; Expected from sequence similarity: Human, Mouse, Rat, Cow
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration
100ug specific antibody in 200ul (lot specific)
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.
Antibody/Peptide Pairs
MRG/MORF4L binding protein peptide (MBS427801) is used for blocking the activity of MRG/MORF4L antibody (MBS422905)
Molecular Weight
22,417 Da
OMIM
611157
Immunogen
Peptide with sequence CIRDKFSQNIGRQVP, from the internal region of the protein sequence according to NP_060740.1.
Epitope
Internal region
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Applications Tested/Suitable for anti-MRGBP antibody
Peptide ELISA (EIA), Western Blot (WB)
Application Notes for anti-MRGBP antibody
Peptide ELISA: Antibody detection limit dilution 1: 32000.
Western Blot: Approx 21kDa band observed in Human Testis lysates (calculated MW of 22.4kDa according to NP_060740.1). Recommended concentration: 0.3-1ug/ml.

Western Blot (WB) of anti-MRGBP antibody

(0.3ug/ml) staining of Human Testis lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Goat Anti-MRGBP Polyclonal Antibody – Cat# MBS422905

Other Notes

Small volumes of anti-MRGBP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for MRGBP. It may not necessarily be applicable to this product.

NCBI GI #
8922764
NCBI GeneID
55257
NCBI Accession #
NP_060740.1
UniProt Secondary Accession #
A8C4L5
UniProt Related Accession #
Q9NV56
GenBank Nucleotide #
NM_018270.5
NCBI Official Full Name
MRG/MORF4L-binding protein
NCBI Official Synonym Full Names
MRG/MORF4L binding protein
NCBI Official Symbol
MRGBP
NCBI Official Synonym Symbols
Eaf7; URCC4; MRG15BP; C20orf20
UniProt Protein Name
MRG/MORF4L-binding protein
UniProt Synonym Protein Names
MRG-binding protein; Up-regulated in colon cancer 4; Urcc4
Protein Family
MRG/MORF4L-binding protein
UniProt Gene Name
MRGBP
UniProt Synonym Gene Names
C20orf20; Urcc4
UniProt Entry Name
MRGBP_HUMAN
NCBI Protein Information
MRG/MORF4L-binding protein

UniProt Comments for MRGBP

MRGBP: Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage. Belongs to the EAF7 family.

Protein type: Acetyltransferase

Chromosomal Location of Human Ortholog: 20q13.33

Cellular Component: NuA4 histone acetyltransferase complex; nucleoplasm; nucleus

Molecular Function: protein binding

Biological Process: histone acetylation; regulation of growth; regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent
Show more

Research Articles on MRGBP

1. role in tumorogenesis of cutaneous squamous cell carcinoma

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-MRGBP antibody

 Reference Product  PubMed Publications
 MORF4L1 antibody  >5 publications with MRGBP and MORF4L1
 KAT5 antibody  >2 publications with MRGBP and KAT5
 BRD8 antibody  >1 publications with MRGBP and BRD8
 DMAP1 antibody  >1 publications with MRGBP and DMAP1

Pathways associated with anti-MRGBP antibody

 Products by Pathway  Pathway Diagram
 Chromatin Modifying Enzymes Pathway antibodies  Chromatin Modifying Enzymes Pathway Diagram
 Chromatin Organization Pathway antibodies  Chromatin Organization Pathway Diagram
 HATs Acetylate Histones Pathway antibodies  HATs Acetylate Histones Pathway Diagram

Organs/Tissues associated with anti-MRGBP antibody

 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >1 publications with MRGBP and Kidney
 Prostate Antibodies  >1 publications with MRGBP and Prostate
 Brain Antibodies  >1 publications with MRGBP and Brain
 Testis Antibodies  >1 publications with MRGBP and Testis
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