Goat Anti-POU2F2 Polyclonal Antibody – Cat# MBS422992

(0.5ug/ml) staining of Human Thymus lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

POU2F2 Antibody – Goat Polyclonal

Name: POU2F2 Antibody; Polyclonal; Goat; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS422992
Price: 450 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS422992

MBS422992 is an antibody targeting POU2F2. Also known as Goat anti-POU2F2/OCT2 Antibody. Reactive in Tested: Human; Expected from sequence similarity: Human, Mouse, Rat, Dog, Pig. Host: Goat. More details

$450 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

POU2F2/OCT2, Polyclonal Antibody

Full Product Name

Goat anti-POU2F2/OCT2 Antibody

Product Gene Name

anti-POU2F2 antibody

Product Synonym Gene Name

OCT2

Product Synonym Names

Goat Anti-POU2F2 / OCT2 Antibody; POU2F2; POU class 2 homeobox 2; OCT2; OTF2; Oct-2; POU domain, class 2, transcription factor 2; homeobox protein; homeobox protein antibody; OCT2 antibody; Oct-2 antibody; OTF2 antibody; POU class 2 homeobox 2 antibody; POU domain; class 2; transcription factor 2 antibody; POU2F2 antibody; POU2F2 / OCT2

Immunogen Sequence

SPTGPSTKIK AED

Clonality

Polyclonal

Host

Goat

Species Reactivity

Tested: Human; Expected from sequence similarity: Human, Mouse, Rat, Dog, Pig

Form/Format

Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Purity/Purification

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Concentration

100ug specific antibody in 200ul (lot specific)

Preparation and Storage

Aliquot and store at -20 degree C. Minimize freezing and thawing.

Antibody/Peptide Pairs

POU2F2 / OCT2 peptide (MBS427865) is used for blocking the activity of POU2F2/OCT2 antibody (MBS422992)

Molecular Weight

62,172 Da

OMIM

164176

Immunogen

Peptide with sequence C-SPTGPSTKIKAED, from the internal region of the protein sequence according to NP_002689.1.

Epitope

Internal region

ISO Certification

Manufactured in an ISO 9001:2008 Certified Laboratory.

Applications Tested/Suitable for anti-POU2F2 antibody

Peptide ELISA (EIA), Western Blot (WB)

Application Notes for anti-POU2F2 antibody

Peptide ELISA: Antibody detection limit dilution 1: 64000.

Other Notes

Small volumes of anti-POU2F2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for POU2F2. It may not necessarily be applicable to this product.

NCBI GI #

4505959

NCBI GeneID

5452

NCBI Accession #

NP_002689.1

UniProt Secondary Accession #

Q16648; Q7M4M8; Q9BRS4

UniProt Related Accession #

P09086

GenBank Nucleotide #

NM_002698.4

NCBI Official Full Name

POU domain, class 2, transcription factor 2 isoform 2

NCBI Official Synonym Full Names

POU class 2 homeobox 2

NCBI Official Symbol

POU2F2

NCBI Official Synonym Symbols

OCT2; OTF2; Oct-2

UniProt Protein Name

POU domain, class 2, transcription factor 2

UniProt Synonym Protein Names

Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2; Octamer-binding protein 2; Oct-2; Octamer-binding transcription factor 2; OTF-2

Protein Family

POU domain, class 2, transcription factor

UniProt Gene Name

POU2F2

UniProt Synonym Gene Names

OCT2; OTF2; Oct-2; OTF-2

UniProt Entry Name

PO2F2_HUMAN

NCBI Protein Information

POU domain, class 2, transcription factor 2

NCBI Summary for POU2F2

The protein encoded by this gene is a homeobox-containing transcription factor of the POU domain family. The encoded protein binds the octamer sequence 5'-ATTTGCAT-3', a common transcription factor binding site in immunoglobulin gene promoters. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

UniProt Comments for POU2F2

Oct2: Transcription factor that specifically binds to the octamer motif (5'-ATTTGCAT-3'). Regulates transcription in a number of tissues in addition to activating immunoglobulin gene expression. Modulates transcription transactivation by NR3C1, AR and PGR. Isoform 5 activates the U2 small nuclear RNA (snRNA) promoter. Belongs to the POU transcription factor family. Class- 2 subfamily. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 19q13.2

Cellular Component: cytoplasm; nucleoplasm; nucleus

Molecular Function: protein domain specific binding; sequence-specific DNA binding; transcription factor activity

Biological Process: cell maturation; humoral immune response; immunoglobulin secretion during immune response; mature B cell differentiation; positive regulation of transcription from RNA polymerase II promoter; snRNA transcription from RNA polymerase II promoter; transcription from RNA polymerase II promoter

Research Articles on POU2F2

1. a differential control exerted by both Oct-1 and Oct-2 in the transcriptional regulation of the HMGA1 gene

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-POU2F2 antibody

Reference Product	PubMed Publications
POU2AF1 antibody	>39 publications with POU2F2 and POU2AF1
CD36 antibody	>6 publications with POU2F2 and CD36
SYK antibody	>1 publications with POU2F2 and SYK
RELA antibody	>1 publications with POU2F2 and RELA

Pathways associated with anti-POU2F2 antibody

Products by Pathway	Pathway Diagram
BCR Signaling Pathway antibodies	BCR Signaling Pathway Diagram
Gene Expression Pathway antibodies	Gene Expression Pathway Diagram
RNA Polymerase II Transcribes SnRNA Genes Pathway antibodies	RNA Polymerase II Transcribes SnRNA Genes Pathway Diagram
SIDS Susceptibility Pathways antibodies	SIDS Susceptibility Pathways Diagram

Diseases associated with anti-POU2F2 antibody

Disease Name	Pubmed Publications
Immune System Diseases Antibodies	>34 publications with POU2F2 and Immune System Diseases
Cardiovascular Diseases Antibodies	>6 publications with POU2F2 and Cardiovascular Diseases
Cell Transformation, Neoplastic Antibodies	>4 publications with POU2F2 and Cell Transformation, Neoplastic
Nervous System Diseases Antibodies	>3 publications with POU2F2 and Nervous System Diseases
Inflammation Antibodies	>3 publications with POU2F2 and Inflammation
Breast Neoplasms Antibodies	>2 publications with POU2F2 and Breast Neoplasms
Disease Models, Animal Antibodies	>2 publications with POU2F2 and Disease Models, Animal
Necrosis Antibodies	>2 publications with POU2F2 and Necrosis
Embryo Loss Antibodies	>1 publications with POU2F2 and Embryo Loss
Fibrosis Antibodies	>1 publications with POU2F2 and Fibrosis

Organs/Tissues associated with anti-POU2F2 antibody

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>121 publications with POU2F2 and Blood
Brain Antibodies	>23 publications with POU2F2 and Brain
Lymph Node Antibodies	>8 publications with POU2F2 and Lymph Node
Lymph Antibodies	>7 publications with POU2F2 and Lymph
Bone Antibodies	>6 publications with POU2F2 and Bone
Embryonic Tissue Antibodies	>3 publications with POU2F2 and Embryonic Tissue
Liver Antibodies	>3 publications with POU2F2 and Liver
Kidney Antibodies	>2 publications with POU2F2 and Kidney
Tonsil Antibodies	>2 publications with POU2F2 and Tonsil
Testis Antibodies	>2 publications with POU2F2 and Testis