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GLP-1-R (GLP1R) Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS423129

MBS423129 is an antibody targeting Glp1r. Also known as Goat anti-GLP-1-R (mouse) Antibody. Reactive in Tested: Mouse; Expected from sequence similarity: Mouse. Host: Goat. More details

$450 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
GLP-1-R (Glp1r), Polyclonal Antibody
Full Product Name
Goat anti-GLP-1-R (mouse) Antibody
Product Gene Name
anti-Glp1r antibody
Product Synonym Names
Glp1r; glucagon-like peptide 1 receptor; GLP-1R; GLP1Rc; GLP-1 receptor; GLP-1-R; GLP-1 receptor antibody; Glp1r antibody; GLP-1R antibody; GLP-1-R antibody; GLP1Rc antibody; glucagon-like peptide 1 receptor antibody; GLP-1-R (mouse)
Immunogen Sequence
SKRGERNFPE EQ
Clonality
Polyclonal
Host
Goat
Species Reactivity
Tested: Mouse; Expected from sequence similarity: Mouse
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration
100ug specific antibody in 200ul (lot specific)
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.
Antibody/Peptide Pairs
GLP-1-R peptide (MBS427794) is used for blocking the activity of GLP-1-R antibody (MBS423129)
Molecular Weight
53,028 Da
Immunogen
Peptide with sequence C-SKRGERNFPEEQ, from the internal region of the protein sequence according to NP_067307.2.
Epitope
Internal region
Note
The immunizing peptide represents part of an extracellular region.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Applications Tested/Suitable for anti-Glp1r antibody
Peptide ELISA (EIA), Western Blot (WB)
Application Notes for anti-Glp1r antibody
Peptide ELISA: Antibody detection limit dilution 1: 128000.
Western Blot: Approx 55kDa band observed in Mouse Heart lysates (calculated MW of 53. 0kDa according to NP_067307.2). Recommended concentration: 1-3ug/ml.

Western Blot (WB) of anti-Glp1r antibody

(1ug/ml) staining of Mouse Heart lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Goat Anti-GLP1R Polyclonal Antibody – Cat# MBS423129

Western Blot (WB) of anti-Glp1r antibody

(1ug/ml) staining of Mouse Heart lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Goat Anti-GLP1R Polyclonal Antibody, Western Blot (WB) – Cat# MBS423129

Other Notes

Small volumes of anti-Glp1r antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Glp1r. It may not necessarily be applicable to this product.

NCBI GI #
111378379
NCBI GeneID
14652
NCBI Accession #
NP_067307.2
UniProt Secondary Accession #
Q1JQR8
UniProt Related Accession #
O35659
GenBank Nucleotide #
NM_021332.2
NCBI Official Full Name
glucagon-like peptide 1 receptor
NCBI Official Synonym Full Names
glucagon-like peptide 1 receptor
NCBI Official Symbol
Glp1r
NCBI Official Synonym Symbols
GLP-1R; GLP1Rc
UniProt Protein Name
Glucagon-like peptide 1 receptor
Protein Family
Glucagon-like peptide 1 receptor
UniProt Gene Name
Glp1r
UniProt Synonym Gene Names
GLP-1 receptor; GLP-1-R; GLP-1R
UniProt Entry Name
GLP1R_MOUSE
NCBI Protein Information
glucagon-like peptide 1 receptor

UniProt Comments for Glp1r

GLP1R: This is a receptor for glucagon-like peptide 1. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 2 family.

Protein type: Receptor, GPCR; Membrane protein, multi-pass; Membrane protein, integral; GPCR, family 2

Cellular Component: integral to membrane; integral to plasma membrane; intracellular; membrane; plasma membrane

Molecular Function: G-protein coupled receptor activity; glucagon receptor activity; peptide hormone binding; peptide receptor activity; peptide receptor activity, G-protein coupled; receptor activity; signal transducer activity; transmembrane receptor activity

Biological Process: associative learning; cAMP-mediated signaling; cell surface receptor linked signal transduction; elevation of cytosolic calcium ion concentration; feeding behavior; G-protein coupled receptor protein signaling pathway; G-protein signaling, adenylate cyclase activating pathway; hormone secretion; insulin secretion; learning and/or memory; memory; negative regulation of apoptosis; negative regulation of neuron apoptosis; neuropeptide signaling pathway; positive regulation of blood pressure; positive regulation of cell differentiation; positive regulation of cell proliferation; positive regulation of heart contraction; positive regulation of insulin secretion; positive regulation of transcription from RNA polymerase II promoter; regulation of calcium ion transport; regulation of heart contraction; release of sequestered calcium ion into cytosol; response to glucose stimulus; response to stress; signal transduction
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Research Articles on Glp1r

1. GLP-1R is present in pancreatic acinar cells and that GLP-1 can regulate secretion through its receptor and cAMP signaling pathway.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-Glp1r antibody

 Reference Product  PubMed Publications
 Gip antibody  >104 publications with Glp1r and Gip
 Pomc antibody  >14 publications with Glp1r and Pomc
 Vip antibody  >12 publications with Glp1r and Vip
 Gcg antibody  >12 publications with Glp1r and Gcg
 Iapp antibody  >6 publications with Glp1r and Iapp
 Mc4r antibody  >5 publications with Glp1r and Mc4r
 Pth antibody  >3 publications with Glp1r and Pth
 Crh antibody  >3 publications with Glp1r and Crh
 Adcy8 antibody  >1 publications with Glp1r and Adcy8

Pathways associated with anti-Glp1r antibody

 Products by Pathway  Pathway Diagram
 Class B/2 (Secretin Family Receptors) Pathway antibodies  Class B/2 (Secretin Family Receptors) Pathway Diagram
 G Alpha (s) Signalling Events Pathway antibodies  G Alpha (s) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 GPCRs, Class B Secretin-like Pathway antibodies  GPCRs, Class B Secretin-like Pathway Diagram
 Glucagon-like Peptide-1 (GLP1) Regulates Insulin Secretion Pathway antibodies  Glucagon-like Peptide-1 (GLP1) Regulates Insulin Secretion Pathway Diagram
 Glucagon-type Ligand Receptors Pathway antibodies  Glucagon-type Ligand Receptors Pathway Diagram
 Insulin Secretion Pathway antibodies  Insulin Secretion Pathway Diagram
 Integration Of Energy Metabolism Pathway antibodies  Integration Of Energy Metabolism Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram

Diseases associated with anti-Glp1r antibody

 Disease Name  Pubmed Publications
 Weight Loss Antibodies  >169 publications with Glp1r and Weight Loss
 Hyperglycemia Antibodies  >150 publications with Glp1r and Hyperglycemia
 Hypoglycemia Antibodies  >142 publications with Glp1r and Hypoglycemia
 Disease Models, Animal Antibodies  >123 publications with Glp1r and Disease Models, Animal
 Insulin Resistance Antibodies  >117 publications with Glp1r and Insulin Resistance
 Diabetes Mellitus, Experimental Antibodies  >95 publications with Glp1r and Diabetes Mellitus, Experimental
 Weight Gain Antibodies  >81 publications with Glp1r and Weight Gain
 Vascular Diseases Antibodies  >79 publications with Glp1r and Vascular Diseases
 Inflammation Antibodies  >51 publications with Glp1r and Inflammation
 Heart Diseases Antibodies  >42 publications with Glp1r and Heart Diseases

Organs/Tissues associated with anti-Glp1r antibody

 Organ/Tissue Name  Pubmed Publications
 Mixed Antibodies  >15 publications with Glp1r and Mixed
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